Opendata, web and dolomites

RodBot

Automated Microhandling System for X-ray Crystallography

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 RodBot project word cloud

Explore the words cloud of the RodBot project. It provides you a very rough idea of what is the project "RodBot" about.

supporting    trapped    delivering    liquid    experts    fragility    3d    erc    manually    object    mechanism    protein    crystals    auspices    utilized    catalysis    micro    noncontact    wireless    fragile    molecules    flows    separating    ray    group    fluidic    device    environments    manipulating    varying    manipulation    drug    rodbot    rolls    rising    entities    bottleneck    core    generally    magnetic    transported    harmless    bimolecular    botmed    living    sizes    therapeutic    location    biological    delicate    manipulate    extraction    off    trained    beam    exposure    scientists    microrobot    front    readily    powered    magnetically    surface    structure    harvesting    micromanipulation    precisely    organisms    influence    interactions    few    crystallography    throughput    size    form    crystallized    grant    material    objects    vortex    enzymes    millimeter    suspended    reynolds    proteins    action    penetrate    understand    named    enzymatic    substrate    generates    external    chromatin    individual    microns    loop    macromolecules    lift    environment    intensity   

Project "RodBot" data sheet

The following table provides information about the project.

Coordinator
EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH 

Organization address
address: Raemistrasse 101
city: ZUERICH
postcode: 8092
website: https://www.ethz.ch/de.html

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Switzerland [CH]
 Total cost 148˙885 €
 EC max contribution 148˙885 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2014-PoC
 Funding Scheme ERC-POC
 Starting year 2015
 Duration (year-month-day) from 2015-09-01   to  2017-02-28

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH CH (ZUERICH) coordinator 148˙885.00

Map

 Project objective

Crystallography is one of the most important methods for studying the 3D structure of complex biological macromolecules. The knowledge of the detailed structure of proteins, enzymes and chromatin allows scientists to understand concepts such as bimolecular interactions, mechanism of enzymatic catalysis and the therapeutic action of drug molecules. A major bottleneck of high-throughput crystallography is harvesting the crystallized form of these molecules from their liquid environments and manipulating them to a location that enables exposure to the X-ray beam. Due of the fragility and large size range of crystals this step has so far been done manually by trained experts.

The proposed research will advance the concept of using a wireless, magnetically driven microrobot, named the RodBot, for micromanipulation of delicate biological entities. The RodBot rolls on a supporting surface in a low Reynolds number fluidic environment and generates rising flows in front of it, and a vortex above it. The flows are utilized for noncontact micromanipulation of fragile objects such as protein crystals. As the RodBot approaches a micro-object, the object comes under the influence of the rising flows which lift it off the substrate. The suspended object is then trapped in the vortex and can be transported to a pre-defined location. The RodBot is powered and controlled by external, low intensity magnetic fields which are generally harmless to living organisms and can readily penetrate most biological material. The flows generated by the RodBot can precisely manipulate crystals of sizes varying from a few microns up to one millimeter. It is capable of separating individual crystals from a group and delivering it to an extraction device called the loop.

The core magnetic manipulation technology for the wireless control of the RodBot has been developed under the auspices of the ERC Advanced grant project BOTMED.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "RODBOT" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "RODBOT" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.1.)

ENTRAPMENT (2019)

Septins: from bacterial entrapment to cellular immunity

Read More  

EASY-IPS (2019)

a rapid and efficient method for generation of iPSC

Read More  

HBPTC (2019)

Hydrogen Bonding Phase Transfer Catalysis

Read More