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GLIOMARK SIGNED

Validation of blood-brain-barrier permeability as a glioma biomarker by means of the radiotracer 99mTc-tetrofosmin and single-photon emission computer tomography

Total Cost €

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EC-Contrib. €

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Partnership

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 Outcomes and results

 GLIOMARK project word cloud

Explore the words cloud of the GLIOMARK project. It provides you a very rough idea of what is the project "GLIOMARK" about.

poor    tumor    grading    selling    safe    subsequent    gliomas    validated    sme    orphan    specificity    radiotracer    mography    reproducibility    diagnosis    objective    reliably    instructions    blood    technique    detect    aggregated    computer    handling    latter    tomography    approval    confirmation    proactina    exclude    combination    biopsies    point    vivo    permeability    assesses    reliability    speciality    preparation    first    ttf    prognosis    pertechnetate    grade    distinguish    hospitals    tolerated    tlr    disease    photon    affordable    fast    biomarker    sensitivity    gliomark    rare    accomplished    containing    niche    spect    diagnostic    emission    invasive    brain    therapies    differential    outcome    hence    99mtc    innovative    glioma    validate    expensive    exclusivity    imaging    magnetic    yield    bbb    greek    tetrofosmin    replace    single    global    unable    chemical    diseases    gliotect    designation    sale    lifted    diagnostics    barrier    leader    clinically    diagnose    reconstituted    resonance    kit    aggressiveness    guarantee    opportunity    market   

Project "GLIOMARK" data sheet

The following table provides information about the project.

Coordinator		 CONSULTECH TECHNOLOGIEBERATUNG GMBH 

Organization address
address: MORGENSTERNSTRASSE 24
city: BERLIN
postcode: 12207
website: www.consultech.de

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.
 Coordinator Country Germany [DE]
 Project website http://www.gliomark.eu
 Total cost 4˙705˙344 €
 EC max contribution 4˙705˙344 € (100%)
 Programme 1. H2020-EU.3.1.3. (Treating and managing disease)
 Code Call H2020-SMEINST-2-2014
 Funding Scheme SME-2
 Starting year 2015
 Duration (year-month-day) from 2015-07-01   to  2019-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    CONSULTECH TECHNOLOGIEBERATUNG GMBH DE (BERLIN) coordinator 3˙167˙094.00
2    PRO-ACTINA CHIMIKI TECHNOLOGIA ANONIMI ETAIRIA EL (MAROUSI ATHENS) participant 1˙538˙250.00

Map

 Project objective

Objective of GLIOMARK is to clinically validate the permeability of the blood brain barrier (BBB) as an in vivo biomarker for the diagnosis and grading of gliomas. This will be accomplished by means of the radiotracer 99mTc-tetrofosmin (TTF) and the imaging technique Single-Photon Emission Computer To-mography (SPECT). The outcome of GLIOMARK is GlioTect, a diagnostic kit containing handling/diagnostic instructions and tetrofosmin. The latter has to be reconstituted with 99mTc pertechnetate to yield TTF, which will be used in combination with SPECT. Often computer tomography or magnetic resonance imaging are unable to detect low-grade gliomas or distinguish glioma from other diseases. Hence, brain biopsies are necessary for confirmation of diagnosis and grading of gliomas. GlioTect with TTF/SPECT enables reliable, fast differential diagnosis and grading of gliomas as non-invasive method. This has an immediate impact on the type and aggressiveness of subsequent therapies. Gliomas are recognized as a rare tumor disease with poor prognosis and orphan diagnostic designation for GlioTect will guarantee 10 years of market exclusivity upon approval. ProActina, a Greek chemical-speciality SME having identified this innovative niche market opportunity could become global market leader in glioma diagnostics. Development is at TLR level 6-7 and will be lifted to 9. Expected market application is the sale of GlioTect for preparation of TTF for use with SPECT. End users are hospitals that use the kit to reliably diagnose or exclude gliomas without the need for expensive equipment. Taken together, the aggregated unique selling point of SPECT in combination with TTF (generated by means of GlioTect) is the first ever and only glioma diagnostic, which assesses a clinically validated glioma biomarker, has high reliability, reproducibility, sensitivity, as well as specificity, which is used to replace an invasive method, is safe, well tolerated, widely available and more affordable

 Deliverables

List of deliverables.
Set up project homepage Websites, patent fillings, videos etc. 2019-07-25 13:49:19

Take a look to the deliverables list in detail:  detailed list of GLIOMARK deliverables.

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The information about "GLIOMARK" are provided by the European Opendata Portal: CORDIS opendata.

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