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BioCapture SIGNED

Smart capture phases for proteomics, glycomics and biomarker assays

Total Cost €

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EC-Contrib. €

0

Partnership

0

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 BioCapture project word cloud

Explore the words cloud of the BioCapture project. It provides you a very rough idea of what is the project "BioCapture" about.

esrs    spectrum    stage    peptide    forms    molecularly    biocapture    packages    separation    platforms    multiplex    enrichment    faster    companies    discovery    mass    health    biomarkers    innovative    15    follow    diagnostic    polymers    posttranslational    ing    chemistry    translational    groups    form    drug    total    spectrometry    format    combined    identification    whereof    coupling    artificial    biochemistry    performed    care    interdisciplinary    fluorescence    expert    fractionation    polymer    readout    receptors    11    laboratories    reaction    technological    antibodies    revealing    assaying    followed    earlier    entrepreneurial    capture    assays    proteins    ms    modifications    binders    consisting    imprinted    basis    biomarker    monitoring    alongside    peptides    detection    proteotypic    multiple    plastic    company    profit    phases    proteinaceous    protein    cancer    sequence    skills    training    molecular    imprinting    glycan    business    scientific    mips    post    materials    elusive    tools    array    abundant    balanced    diseases    diagnosis    techniques   

Project "BioCapture" data sheet

The following table provides information about the project.

Coordinator
MALMO UNIVERSITET 

Organization address
address: NORDENSKIOLDSGATAN 1
city: MALMOE
postcode: 205 06
website: www.mah.se

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Sweden [SE]
 Project website http://www.biocapture.mau.se
 Total cost 2˙982˙878 €
 EC max contribution 2˙982˙878 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2016
 Funding Scheme MSCA-ITN-ETN
 Starting year 2016
 Duration (year-month-day) from 2016-11-01   to  2020-10-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    MALMO UNIVERSITET SE (MALMOE) coordinator 565˙670.00
2    KOBENHAVNS UNIVERSITET DK (KOBENHAVN) participant 580˙163.00
3    UNIVERSITETET I OSLO NO (OSLO) participant 445˙317.00
4    SYDDANSK UNIVERSITET DK (ODENSE M) participant 322˙313.00
5    UNIVERSITY OF STRATHCLYDE UK (GLASGOW) participant 273˙287.00
6    BUNDESANSTALT FUER MATERIALFORSCHUNG UND -PRUEFUNG DE (BERLIN) participant 268˙807.00
7    LINNEUNIVERSITETET SE (VAXJO) participant 263˙659.00
8    UMEA UNIVERSITET SE (UMEA) participant 263˙659.00
9    Biotage SE (LUND) partner 0.00
10    GT Septech NO (TROLLASEN) partner 0.00
11    LUNDS UNIVERSITET SE (LUND) partner 0.00
12    ReSyn Biosciences ZA (Edenvale) partner 0.00
13    THE UNIVERSITY OF MANCHESTER UK (MANCHESTER) partner 0.00
14    UNIVERSITA DEGLI STUDI DI PAVIA IT (PAVIA) partner 0.00

Map

 Project objective

The overall objective of BioCapture is to develop novel robust assays for proteinaceous biomarkers associated with cancer and to develop innovative tools for assaying elusive cancer related posttranslational modifications in proteins. This will be achieved by exploiting robust glycan, peptide and protein binders in the form of Molecularly Imprinted Polymers (MIPs) or plastic antibodies alongside generic enrichment combined with selected reaction monitoring-based mass spectrometry assays. In addition, sequence specific MIPs for multiple proteotypic peptides will be developed for use as capture phases in array format followed by MS or fluorescence based readout as well as a coupling of both detection techniques. The artificial receptors will be developed by various Molecular Imprinting techniques. The research results will lead to technological advances having a major impact on 1) health care since it will profit from methods for earlier, more reliable diagnosis of diseases, 2) drug discovery allowing a faster target or biomarker identification; and 3) biochemistry research laboratories in resulting in improved protein fractionation tools for revealing low abundant post translational modifications. The training of researchers will be performed by a consortium consisting of in total 15 partners whereof 6 polymer/materials research groups, 5 protein/glycan chemistry/analysis groups, 1 separation technology companies, 2 expert groups on platforms for multiplex analysis and one diagnostic company. This forms the basis for a very exciting interdisciplinary training program. Thus 11 early stage researchers (ESRs) working on specific tasks within five work packages will follow a rich training program providing a well-balanced spectrum of scientific, business and entrepreneurial skills.

 Deliverables

List of deliverables.
Project website published and accessible Websites, patent fillings, videos etc. 2019-06-19 13:48:52
Project vacancies advertised Documents, reports 2019-06-19 13:48:51
Produce a project poster and a presentation Websites, patent fillings, videos etc. 2019-06-19 13:48:51

Take a look to the deliverables list in detail:  detailed list of BioCapture deliverables.

 Publications

year authors and title journal last update
List of publications.
2018 Sudhirkumar Shinde, Jayashree Selvalatchmanan, Anil Incel, Maedeh Akhoundian, Anne K. Bendt, Federico Torta
Mesoporous polymeric microspheres with high affinity for phosphorylated biomolecules
published pages: 8603-8608, ISSN: 1144-0546, DOI: 10.1039/C8NJ01114A
New Journal of Chemistry 42/11 2019-06-19
2018 Rashmi Mahajan, Mona Rouhi, Sudhirkumar Shinde, Thomas Bedwell, Anil Incel, Liliia Mavliutova, Sergey Piletsky, Ian Nicholls, Börje K-E Sellergren
Highly efficient synthesis and assay of protein imprinted nanogels using magnetic templates
published pages: , ISSN: 1433-7851, DOI: 10.1002/anie.201805772
Angewandte Chemie International Edition 2019-06-19

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The information about "BIOCAPTURE" are provided by the European Opendata Portal: CORDIS opendata.

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