EU H2020 Project "CETACEAN INNER EAR (Cetacean Inner Ear)": description, partecipants, costs and EC-fundings

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Cetacean Inner Ear project word cloud

Explore the words cloud of the Cetacean Inner Ear project. It provides you a very rough idea of what is the project "Cetacean Inner Ear" about.

regulate source cetaceans decision cochlear makers sensitivities organ responsible expertise once conservation invaluable cell consequence protective france facilities protocol remarkable pollution auditory selectivity morphological signal cetacean immunohistochemistry supporting species caused mechanisms techniques noise whales team permanent scar toothed frequency sound inserm issue imaging ultrastructure marine tools apoptosis fine severe distinguish subsequent consist montpellier inner accomplishment transducing alterations ecosystems formed apoptotic cells ones neurosciences acoustic corti microscopy ear hair conducting play lesions assessing newly replace stranded lethal overexposure maps causing cochlea resolved sensitivity estimate 1051 mechanism tune insulate exposure hearing electron map

Project "Cetacean Inner Ear" data sheet

The following table provides information about the project.

Coordinator	INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE Organization address address: RUE DE TOLBIAC 101 city: PARIS postcode: 75654 website: www.inserm.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	France [FR]
Total cost	185˙076 €
EC max contribution	185˙076 € (100%)
Programme	1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
Code Call	H2020-MSCA-IF-2016
Funding Scheme	MSCA-IF-EF-ST
Starting year	2017
Duration (year-month-day)	from 2017-06-01 to 2019-09-21

#	participants	country	role	EC contrib. [€]
1	INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE	FR (PARIS)	coordinator	185˙076.00

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE

FR (PARIS)

coordinator

185˙076.00

Project objective

The morphological study of cetacean cochlea as well as the possible alterations associated to sound exposure, represent a key conservation issue to assess the effects of acoustic pollution on marine ecosystems. Noise pollution could affect cetaceans by causing lesions in their inner ear, which can be severe enough to be lethal. In cases of severe permanent hearing loss, supporting cells of the organ of Corti replace apoptotic hair cells that are responsible for transducing the signal and enhancing auditory sensitivity and frequency selectivity. The objectives of this study consist in conducting a comparative ultrastructure morphological analysis of the cochlea from stranded cetaceans to 1) to assess their species specific hearing sensitivities by creating cochlear frequency maps and 2) to investigate possible lesions as a consequence of sound overexposure. Once the cochlear frequency map for a species is resolved, it will be possible to estimate the acoustic characteristics of a source that may have caused these lesions. In addition, this study will 3) investigate the process of hair cell apoptosis and the subsequent ‘scar’ formation to be able to distinguish newly formed lesions from old ones. Toothed whales have remarkable hearing protective mechanisms to insulate them from noise. Our research will also focus on 4) examining the potential elements that might play a role in this protective mechanism. To achieve these four objectives, the applicant will fine tune the protocol of ear analysis using electron microscopy and applying immunohistochemistry techniques. The expertise of the Hearing team of the Institute for Neurosciences of Montpellier (Inserm Unit 1051, France), and its microscopy and imaging facilities will be invaluable for the accomplishment of our study. This research will bring tools to the decision makers to better regulate marine activities and will contribute with essential knowledge for assessing the effects of noise pollution cetacean hearing.

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