Opendata, web and dolomites


Quantifying bio-nano interactions of nanoparticles through microfluidic live cell Raman spectroscopy

Total Cost €


EC-Contrib. €






 qBioNano project word cloud

Explore the words cloud of the qBioNano project. It provides you a very rough idea of what is the project "qBioNano" about.

combine    3d    maintained    mitochondria    live    time    questions    interdisciplinary    first    microfluidic    molly    quality    free    nano    odowska    bio    imperial    materials    destructive    rs    qbionano    prof    cellular    raman    supervision    alkyne    extensive    spatiotemporally    healthy    particle    platform    cells    biological    diseased    spectra    interactions    highest    underlying    environments    as    world    biology    governing    microfluidics    runs    biostructures    tissue    spectroscopy    answer    london    nuclei    expertise    assembly    label    group    science    engineered    situated    biomaterials    visible    imaging    assembled    quantifying    lipids    biomolecules    layer    view    interact    resolved    college    class    containing    interfaces    urgent    spheroids    polymers    lbl    marie    nps    physiological    icl    sk    quantification    uniquely    cell    combining    physiologically    proteins    invasive    curie    stevens    fellow    nanoparticles    tissues   

Project "qBioNano" data sheet

The following table provides information about the project.


Organization address
city: LONDON
postcode: SW7 2AZ

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Project website
 Total cost 195˙454 €
 EC max contribution 195˙454 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2016
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2017
 Duration (year-month-day) from 2017-08-21   to  2019-08-20


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 


 Project objective

As a Marie SkÅ‚odowska-Curie Fellow in “qBioNano: Quantifying bio-nano interactions of nanoparticles through microfluidic live cell Raman spectroscopy”, I will combine three emerging fields—layer-by-layer (LbL) assembly of nanoparticles (NPs), microfluidics, and live cell Raman spectroscopy (RS)—to enable 3D imaging and quantification of how NPs and cells interact under physiological conditions. This will allow, for the first time, non-invasive, non-destructive, label-free, spatiotemporally resolved study of a range of biomolecules (e.g., lipids and proteins) and biostructures (e.g., nuclei and mitochondria) at the same time as LbL assembled NPs to answer long-standing questions on particle-induced changes in cellular states and processes. The NPs will be produced through LbL assembly of alkyne-containing polymers (having Raman spectra clearly visible in biological environments), and—using microfluidic devices (where cells can be introduced and maintained in physiologically relevant environments)—I will study how these NPs affect both healthy and diseased cells and tissues (e.g., at cell-cell interfaces and using spheroids). This project will provide: (i) the first detailed view into the biology underlying cellular responses to LbL assembled NPs under physiological conditions, and (ii) a new platform offering insight into key cellular processes and responses governing how cells and tissues interact with, and respond to, engineered NPs. By combining my expertise in developing NPs, microfluidic systems and investigating bio-nano interactions, with the supervision of Prof. Molly Stevens at Imperial College London (ICL), who runs a world-class interdisciplinary biomaterials group with extensive experience in RS, materials science, and cell and tissue biology, this project is uniquely situated to address these urgent—but challenging—topics and deliver the highest quality results.


year authors and title journal last update
List of publications.
2018 Matthew Faria, Mattias Björnmalm, Kristofer J. Thurecht, Stephen J. Kent, Robert G. Parton, Maria Kavallaris, Angus P. R. Johnston, J. Justin Gooding, Simon R. Corrie, Ben J. Boyd, Pall Thordarson, Andrew K. Whittaker, Molly M. Stevens, Clive A. Prestidge, Christopher J. H. Porter, Wolfgang J. Parak, Thomas P. Davis, Edmund J. Crampin, Frank Caruso
Minimum information reporting in bio–nano experimental literature
published pages: 777-785, ISSN: 1748-3387, DOI: 10.1038/s41565-018-0246-4
Nature Nanotechnology 13/9 2019-11-11
2019 Matthew Faria, Ka Fung Noi, Qiong Dai, Mattias Björnmalm, Stuart T. Johnston, Kristian Kempe, Frank Caruso, Edmund J. Crampin
Revisiting cell–particle association in vitro: A quantitative method to compare particle performance
published pages: 355-367, ISSN: 0168-3659, DOI: 10.1016/j.jconrel.2019.06.027
Journal of Controlled Release 307 2019-11-11

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "QBIONANO" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email ( and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "QBIONANO" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.3.2.)

GENESE 17 (2018)

Geometries of Exotic NuclEar StructurE 17

Read More  

ACES (2019)

Antarctic Cyclones: Expression in Sea Ice

Read More  


Simulations of Topological Phases in Superconducting Circuits

Read More