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EvoCELL SIGNED

Animal evolution from a cell type perspective: multidisciplinary training in single-cell genomics, evo-devo and in science outreach

Total Cost €

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EC-Contrib. €

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Partnership

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Project "EvoCELL" data sheet

The following table provides information about the project.

Coordinator
EUROPEAN MOLECULAR BIOLOGY LABORATORY 

Organization address
address: Meyerhofstrasse 1
city: HEIDELBERG
postcode: 69117
website: http://www.embl.de

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Total cost 3˙794˙519 €
 EC max contribution 3˙794˙519 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2017
 Funding Scheme MSCA-ITN-ETN
 Starting year 2018
 Duration (year-month-day) from 2018-01-01   to  2021-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    EUROPEAN MOLECULAR BIOLOGY LABORATORY DE (HEIDELBERG) coordinator 581˙505.00
2    CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS FR (PARIS) participant 679˙095.00
3    THE UNIVERSITY OF EXETER UK (EXETER) participant 364˙383.00
4    UNIVERSITY COLLEGE LONDON UK (LONDON) participant 364˙383.00
5    UNIVERSITETET I BERGEN NO (BERGEN) participant 357˙844.00
6    STAZIONE ZOOLOGICA ANTON DOHRN IT (NAPOLI) participant 344˙081.00
7    MUSEUM FUR NATURKUNDE - LEIBNIZ-INSTITUT FUR EVOLUTIONS- UND BIODIVERSITATSFORSCHUNG AN DER HUMBOLDT-UNIVERSITAT ZU BERLIN DE (BERLIN) participant 332˙288.00
8    UPPSALA UNIVERSITET SE (UPPSALA) participant 263˙659.00
9    GENOMIX4LIFE SRL IT (BARONISSI) participant 258˙061.00
10    RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG DE (HEIDELBERG) participant 249˙216.00

Map

 Project objective

One of the first events in the evolution of multicellular animals was the differentiation of cells into distinct types with different roles. Starting from their most simple multicellular ancestors, the cells that compose animal bodies have become increasingly diverse; each cell type distinguished by the unique set of genes it expresses. This increase in diversity of cell types over evolutionary time is recapitulated in the process of development during which a single undifferentiated cell - the fertilised egg - divides and its progeny differentiate into the countless cell types of the adult body. Currently we do not even know how many distinct cell types animals posses, how new cell types arise in evolution, how many are in common between different animal groups and how many unique cell types have evolved in different lineages. Our aim in EvoCELL is to lay the foundation for a new branch of evo-devo focussing on cell types. We will study these fundamental questions in animal evolution and development using a new technology - single cell sequencing - which we will for the first time employ outside of lab models to sample the great diversity of animal phyla. Europe is home to world-leading expertise in evo-devo and single-cell genomics, but research and training efforts are as yet uncoordinated and their potential for synergy underexplored. EvoCELL will harness and expand this European excellence by training a new generation of multidisciplinary scientists skilled in exploring the vast breadth of animal differentiation. We will jointly sample data from all major animal lineages, richly represented in the biodiversity of European waters, and develop new tools for comparative analyses, through which we will together pioneer three branches of cell evo-devo: evolution of stem cells; emergence of animal life cycles, and the stunning diversity of neural cell types.

 Deliverables

List of deliverables.
Website Websites, patent fillings, videos etc. 2020-04-16 14:24:34
Practical Course II Other 2020-04-16 14:24:30
Practical Course I Other 2020-04-16 14:24:25

Take a look to the deliverables list in detail:  detailed list of EvoCELL deliverables.

 Publications

year authors and title journal last update
List of publications.
2018 Margherita Perillo, Periklis Paganos, Teresa Mattiello, Maria Cocurullo, Paola Oliveri, Maria I. Arnone
New Neuronal Subtypes With a “Pre-Pancreatic” Signature in the Sea Urchin Stongylocentrotus purpuratus
published pages: 1-12, ISSN: 1664-2392, DOI: 10.3389/fendo.2018.00650
Frontiers in Endocrinology 9 2020-01-30
2019 Assunta Sellitto, Konstantinos Geles, Ylenia D’Agostino, Marisa Conte, Elena Alexandrova, Domenico Rocco, Giovanni Nassa, Giorgio Giurato, Roberta Tarallo, Alessandro Weisz, Francesca Rizzo
Molecular and Functional Characterization of the Somatic PIWIL1/piRNA Pathway in Colorectal Cancer Cells
published pages: 1390, ISSN: 2073-4409, DOI: 10.3390/cells8111390
Cells 8/11 2020-01-30
2019 Milena Marinković, Jürgen Berger, Gáspár Jékely
Neuronal coordination of motile cilia in locomotion and feeding
published pages: , ISSN: 0962-8436, DOI:
Phil. Trans. R. Soc. B 2019-12-17

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The information about "EVOCELL" are provided by the European Opendata Portal: CORDIS opendata.

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