EU H2020 Project "SENSE2SURVIVESALT (Surviving salinity: How do plants sense Na+?)": description, partecipants, costs and EC-fundings

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Sense2SurviveSalt project word cloud

Explore the words cloud of the Sense2SurviveSalt project. It provides you a very rough idea of what is the project "Sense2SurviveSalt" about.

root follow global na salinity genomics irrigated wp4 6 sodium planta gap subsequent economically function assays wp2 biochemical candidates wp5 proof food genome elucidation arabidopsis wp1 mutant stress varieties proteins improvement thaliana parallel bending perception programs salt screens sensing initial security total inhibition sensor tolerance mutants combining genetic natural silico genes interactors elusive plant gravity impair world chemical reveal detrimental agriculture land crop saline directions modulating putative cope tomato salinization soils localization modules innovative ions variation mechanism 20 compounds screen plants marginal monumental discovered threat ultimately wp3 sensors area soil candidate model complementary phenotyping affinity

Project "Sense2SurviveSalt" data sheet

The following table provides information about the project.

Coordinator	WAGENINGEN UNIVERSITY Organization address address: DROEVENDAALSESTEEG 4 city: WAGENINGEN postcode: 6708 PB website: http://www.wageningenur.nl/nl.htm contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Netherlands [NL]
Total cost	1˙999˙843 €
EC max contribution	1˙999˙843 € (100%)
Programme	1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
Code Call	ERC-2016-COG
Funding Scheme	ERC-COG
Starting year	2018
Duration (year-month-day)	from 2018-01-01 to 2022-12-31

#	participants	country	role	EC contrib. [€]
1	WAGENINGEN UNIVERSITY	NL (WAGENINGEN)	coordinator	1˙999˙843.00

WAGENINGEN UNIVERSITY

NL (WAGENINGEN)

coordinator

1˙999˙843.00

Project objective

A major gap in our knowledge of how plants respond to soil salinity is their initial perception of sodium (Na) ions. Salt is detrimental to plants and soil salinization is an increasing threat to global food security; 6% of the world’s total land area and 20% of irrigated land is affected by salinity. I recently discovered Na-specific root growth responses of plants and will now exploit these to identify the elusive sodium sensing mechanism of plants. I will use an innovative approach combining genome-wide genetic screens in the model plant Arabidopsis thaliana with dedicated biochemical assays. I will identify candidate Na-sensor genes through a natural genetic variation screen for the Na-specific inhibition bending of the root in response to gravity (WP1). In parallel, I will follow a chemical genomics approach to find novel compounds that impair Na sensing, and their target proteins in plants (WP2). Subsequent complementary in silico and biochemical approaches will characterize Na-affinity of the candidates (WP3). Selected putative Na sensors will be characterized in planta, by studying their localization, activity, their interactors, and by salt response phenotyping of mutants (WP4). Finally, mutant varieties of sensors will be introduced in the economically relevant crop plant tomato, to provide proof-of-concept for improving salt tolerance by modulating sensor function and implementation in crop improvement programs (WP5). The impact of elucidation of plant Na sensing will be monumental; it will reveal how plant responses to salinity stress are driven, and ultimately what is required to cope with salinity. In addition, it will open up new applied directions for agriculture, where improved sodium sensing modules will be used to allow crop growth on marginal, saline soils.

Deliverables

List of deliverables.
Data Management Plan	Open Research Data Pilot	2020-03-06 18:35:22

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