Opendata, web and dolomites
H2020 projects about "inhibition"
The page lists 163 projects related to the topic "inhibition".
| # | |||
|---|---|---|---|
| 1 | FAIR-PARK-II | Conservative iron chelation as a disease-modifying strategy in Parkinson’s disease: a multicentric, parallel-group, placebo-controlled, randomized clinical trial of deferiprone | 2015 |
| 2 | REGAIN | REgeneration of inner ear hair cells with GAmma-secretase INhibitors to regain hearing in patients with sensorineural hearing loss | 2015 |
| 3 | CannaPreg | Development of pregnenolone derivatives as allosteric inhibitors of CB1 cannabinoid receptors for the treatment of schizophrenia and psychotic syndromes | 2015 |
| 4 | RncRNAA | Functions of non-coding RNAs in protein synthesis and homeostasis during aging | 2015 |
| 5 | ISOTRAPSS | Isoform specific inhibition by transient protein state stabilization | 2015 |
| 6 | MBLIs | New Approaches to Metallo-β-Lactamase Inhibitors | 2015 |
| 7 | ChemoBOOM | Development of Palladium-Labile Prodrugs for Bioorthogonally-Activated Chemotherapy | 2016 |
| 8 | SCEL-TA | Surfactant controlled Cation Exchange Lithography - Towards Application | 2015 |
| 9 | NovLeuReg | Identification and characterization of novel essential regulators of acute myeloid leukemia | 2016 |
| 10 | SorCSbalance | Role of the sorting receptor SorCS1 in controlling excitation/inhibition balance in neural circuits. | 2015 |
| 11 | OPTOFRAX | Optopharmacological brain mapping of autism mouse models | 2015 |
| 12 | LYMPHOSIGN | Integrated study of the role of B-cell receptor signaling in the development of Follicular Lymphoma | 2015 |
| 13 | MetAccembly | Accelerating metal-directed assembly, recognition and catalysis with computational methods | 2015 |
| 14 | CRYOMAT | Antifreeze GlycoProtein Mimetic Polymers | 2015 |
| 15 | DDRNA | DDRNA-based cancer therapy targeted telomeres | 2015 |
| 16 | Inflammostrome | Stromal cells as primary drivers of immunopathology: towards targeted disease modification in spondyloarthritis | 2015 |
| 17 | PNANOMED | Personalized Nanomedicines for Leukemia Patients | 2015 |
| 18 | METALS | Formation and Characterization of Protein Post-Translational Modifications and Assessment of Cellular Responses by Application of Metals in Biological Systems | 2015 |
| 19 | NewEat | Transdiagnostic views on eating disorders and obesity and new approaches for treatment | 2015 |
| 20 | INQMINDS | The Evolutionary and Developmental Origins of Inquiring Minds: Studies of Causal Reasoning; Curiosity and Executive Control | 2015 |
| 21 | HomeoBalanceExcInh | Homeostatic balancing of excitation and inhibition in vivo | 2015 |
| 22 | UPR NEURO | The Unfolded Protein Response in Neurodegeneration | 2015 |
| 23 | TRIGGDRUG | Reactions That Translate mRNA into Drug-like Molecules | 2016 |
| 24 | p38Cure | New breast cancer therapies based on available p38 MAPK inhibitors | 2015 |
| 25 | CCT | The psychology and neurobiology of cognitive control training in humans | 2015 |
| 26 | Bcl-Inhib | Discovery of Bcl-3 inhibitors as Potential Chemopreventive Agent for skin cancer | 2015 |
| 27 | HyGlio | Theranostic Injectable Hydrogel for Glioblastoma | 2016 |
| 28 | EVI1inCancer | Overcoming the epigenetic and therapeutic barrier of EVI1-overexpressing cancers | 2016 |
| 29 | PSYCHOCELL | Cellular substrate of abnormal network maturation in neuropsychiatric disorders | 2016 |
| 30 | TARG-SUP | Targeting TGF-β activation, likely the core mechanism of immunosuppression by human regulatory T cells. | 2016 |
| 31 | BrainCrossTalk | Large-scale cortical communication: Brain oscillatory mechanisms of attention allocation and selective inhibition | 2017 |
| 32 | NuSiCC | Modelling the therapeutic potential of NUAK1 suppression in colorectal cancer | 2016 |
| 33 | BIC | Bilingual inhibitory control: N-2 language repetition costs unchained | 2016 |
| 34 | MRCKa in cancer | Targeting Cancer Cell Invasion and Metastasis by Inhibition of the Serine Kinase MRCKa | 2016 |
| 35 | NORVAS | Therapeutic and Biomarker Potential of long non-coding RNAs in Vascular Disease | 2016 |
| 36 | ONCOINTRABODY | Targeting common oncogenes with intracellular monobodies | 2016 |
| 37 | NMDARETT | Cell-type Specific Mechanisms and Functional Consequences of Altered NMDA Receptor Development and Mecp2 Deficiency on Developing Cortical Circuits | 2016 |
| 38 | DYNAPORE | Dynamic responsive porous crystals | 2016 |
| 39 | TMS_ATT | Brain stimulation of attention networks: examining old principles and developing new clinical applications | 2016 |
| 40 | 5HT-DREADD | In vivo pharmacogenetic investigation of 5-HT mechanisms in emotional learning | 2016 |
| 41 | CIL2015 | Dissecting the cellular mechanics of contact inhibition of locomotion | 2016 |
| 42 | Self-Control | Take control!Towards novel training regimes enhancing inhibition and impulse control in health and psychiatric disease | 2016 |
| 43 | PLEIO-RANK | Pleiotropic treatment of cancer: RANK inhibitors targeting cancer stem cells and immunity | 2016 |
| 44 | PROVASC | Cell-specific vascular protection by CXCL12/CXCR4 | 2016 |
| 45 | GBM-CPP | Developing an anti-Myc cell-penetrating peptide for cancer treatment | 2016 |
| 46 | LSDiASD | Leveraging Small Demethylase inhibitors for Autism Spectrum Disorder | 2016 |
| 47 | HOXA9 degradome | Deciphering the machinery involved in stability of the transcription factor HOXA9. | 2016 |
| 48 | PRINT-AID | Multidisciplinary European training network for development of personalized anti-infective medical devices combining printing technologies and antimicrobial functionality | 2017 |
| 49 | Neurogenesis | Exploration and promotion of neurogenesis in the adult brain | 2016 |
| 50 | DeNovoImmunoDesign | Computational Design of Novel Functional Proteins for Immunoengineering | 2017 |
| 51 | BITCAT | Blocking Inhibition of T-cell Co-stimulation for Anti-tumour Therapy | 2017 |
| 52 | NEW DEAL | New siRNA Nanotherapy for Inflammatory Bowel Diseases, targeting Janus kinases | 2017 |
| 53 | CD40-INN | CD40 goes innate: defining and targeting CD40 signaling intermediates in the macrophage to treat atherosclerosis | 2016 |
| 54 | INHIBITHUMAN | Dis-inhibitory circuits in the human cerebral cortex | 2016 |
| 55 | Circdyn | Optical Interrogation of Hippocampal Dentate Granule Circuit Dynamics in Health and Disease | 2017 |
| 56 | PhotoPHYTOMICS | Photosynthesis in PHYTOplankton Mixtures to Investigate Community Structuration. | 2017 |
| 57 | VestibVis | Visual and vestibular processing in secondary visual cortex | 2017 |
| 58 | TSPO METALLODRUGS | Novel, highly effective and selective anticancer metallodrugs | 2018 |
| 59 | CRISTONE | Targeting CRISPR-based HDAC inhibitors to histones: a new tool for assessing mechanisms of class I HDAC inhibitors and developing chemical probes. | 2017 |
| 60 | SHAPPI | Scaffold hybridization approach targeting PPIs | 2017 |
| 61 | CAB | Cognition, ageing, and bilingualism: Investigating age-related changes in bilingual language switching and use. | 2017 |
| 62 | HUNTINFISH | Generation of new zebrafish models for the study of the pathogenesis of Huntington´s disease and for the identification of new therapeutic targets. | 2018 |
| 63 | IVORIaN | RAS/C-RAF interaction: A new pharmacological target in Kras-driven lung cancer. | 2017 |
| 64 | BICEPSvsHIV | Novel strategies for anti-HIV-1 therapy: Small molecules targeting RNA partners of the nucleocapsid protein | 2017 |
| 65 | DUALITY | An Integrated Computational and Experimental Approach to Rapid Synthesis of Highly Selective Dual-Targeted HDAC/CK2, MMP2/CK2 Inhibitors | 2018 |
| 66 | VWF and NETs | Investigating the interplay between VWF, platelets, and neutrophil extracellular traps in pathologies involving thrombosis of the microvasculature | 2017 |
| 67 | EpiPur | The ATP-P2X7R axis: a target for drug-refractory epilepsy | 2018 |
| 68 | REPRODAMH | Extra-gonadal roles of Anti-Müllerian Hormone in the aetiology of polycystic ovary syndrome: the domino effect to reproductive neuroendocrine dysfunctions | 2017 |
| 69 | BETACONTROL | Control of amyloid formation via beta-hairpin molecular recognition features | 2017 |
| 70 | DEVBRAINTRAIN | Neurocognitive mechanisms of inhibitory control training and transfer effects in children | 2017 |
| 71 | DynaCOMP | Assessing compounds targeting DNA replication licensing complexes as anti-tumor agents | 2017 |
| 72 | TelMetab | Telomere metabolism in Genome Stability and Disease | 2017 |
| 73 | TarMyc | Targeting the Oncogenic Function of Myc in vivo | 2018 |
| 74 | TECNEC | Preclinical concept validation of tumor endothelial cell metabolism for novel anti-angiogenic therapy | 2017 |
| 75 | Sense2SurviveSalt | Surviving salinity: How do plants sense Na+? | 2018 |
| 76 | NO-STRESS | Nitric oxide regulation of repolarisation in the heart: role of mechanical stress | 2018 |
| 77 | UPRECON | Ultrafast photonics for the detection and recognition of toxic spine-structures of amyloid aggregates linked to neurodegenerative disease | 2018 |
| 78 | CESYDE | Ceramide Synthases in Diabetic Beta Cell Demise | 2018 |
| 79 | BioRECO2VER | Biological routes for CO2 conversion into chemical building blocks | 2018 |
| 80 | InnovaConcrete | Innovative materials and techniques for the conservation of 20th century concrete-based cultural heritage | 2018 |
| 81 | BoosT | BOOSTing the industrial application of green carbides by thermal spraying in protective coatings | 2018 |
| 82 | CMTaaRS | Defective protein translation as a pathogenic mechanism of peripheral neuropathy | 2018 |
| 83 | CLLCLONE | Harnessing clonal evolution in chronic lymphocytic leukemia | 2018 |
| 84 | CALLAX | What is the role of the axonal connections between the hemispheres in sensory processing? | 2018 |
| 85 | SYNFOS | Synthetic toolkit for fragment oriented synthesis | 2018 |
| 86 | BrainBehaviourModel | Understanding decision making by linking brain and behaviour | 2018 |
| 87 | DC-SIGN-MFN | Dissecting Multivalent Viral Receptor-carbohydrate Interactions Using Polyvalent Multifunctional Glycan-Quantum Dot | 2018 |
| 88 | EcoGemCoat | Smart anticorrosion coatings based on nanocontainers loaded with novel, eco-friendly cationic gemini surfactants as efficient corrosion inhibitors for carbon steel in seawater. | 2018 |
| 89 | NoMePaCa | Novel Metabolic Pathways in Cancer | 2018 |
| 90 | IN-Fo-trace-DG | Role of GABAergic interneurons in the formation of new memory traces in the Dentate Gyrus ofbehaving mice | 2018 |
| 91 | M-INHIB | Non-linear temporal dynamics of mutually inhibiting pyramidal cells: underlying mechanism for bi-stable perception and disambiguation | 2018 |
| 92 | WolAntiS | Using antisense inhibition to understand Wolbachia symbiosis and antiviral protection | 2019 |
| 93 | VIAR | Virus-induced autophagy restriction | 2018 |
| 94 | rSAMs-NANO | Nanoparticles with switchable shells for virus sensing and inhibition | 2018 |
| 95 | Gal3-BrainMets | A novel immunotherapy against brain metastasis: Anti-Galectin-3 | 2019 |
| 96 | IGpath | Dissecting the functional pathways of B cell receptor immunoglobulin in antigen driven mature B cell lymphomas | 2018 |
| 97 | TUNING-BRAKES | Fine-tuning the brain’s brakes – modulating inhibitory control with transcranial alternating current stimulation | 2019 |
| 98 | C-CLEAR | Complement: to clear or not to clear | 2018 |
| 99 | RaftsStruc | Structural sudies of the bacterial lipid rafts. | 2018 |
| 100 | mTORmorS | Role of mTOR signaling dysregulation in the tumor suppressor networks in hepatocellular carcinoma | 2019 |
| 101 | LIPOMET | Dietary Influences on Metastasis: How, When, and Why | 2018 |
| 102 | SelectiveTGFb-inhib | Pro-tumorigenic effects of TGFb - elucidation of mechanisms and development of selective inhibitors | 2018 |
| 103 | SENCAN | Senescence therapy for cancer | 2018 |
| 104 | 3Dcis | 3D Organization of Functionally Conserved Cis-Regulatory Elements | 2018 |
| 105 | Simecos | A New Adjuvant Nutraceutical from the North Atlantic Ocean for Breast, Lung and Pancreatic Cancer Patients | 2018 |
| 106 | SYST-iMYC | Development of an effective and safe systemic Myc inhibitor for the treatment of multiple cancer types. | 2018 |
| 107 | Growth regulation | The wide-spread bacterial toxin delivery systems and their role in multicellularity | 2019 |
| 108 | REDIFUEL | Robust and Efficient processes and technologies for Drop In renewable FUELs for road transport | 2018 |
| 109 | STIMUNO | Searching for novel strategies improving cancer immunotherapy | 2019 |
| 110 | p38_InTh | Innovative therapeutic tools to ameliorate chemotherapy-induced cardiotoxicity | 2018 |
| 111 | CONQR | Translation and Commercialization of a QSOX1-inhibitory Antibody Targeting the Tumor Microenvironment in Breast Cancer | 2018 |
| 112 | ATHENA | Assays for the identification of Thyroid Hormone axis-disrupting chemicals: Elaborating Novel Assessment strategies | 2019 |
| 113 | PHARMS | Bacteriophage inhibition of antibiotic-resistant pathogenic microbes and founding for novel therapeutic strategies | 2019 |
| 114 | PHOTOMASS | Imaging Biomolecular Self-Assembly with a Molecular Photonic Scale | 2019 |
| 115 | INTEGRATE | An integrated hypothesis for cognitive and positive symptoms in schizophrenia | 2018 |
| 116 | ArthritisHeal | Establishing the molecular fundamentals of arthritic diseases – a step forward to Heal Arthritis | 2019 |
| 117 | INSPIRE | INNOVATIVE GROUND INTERFACE CONCEPTS FOR STRUCTURE PROTECTION | 2019 |
| 118 | PsychAID | Psychiatric Disorders: ATX-inhibiting drugs as a new therapeutic option: Proof-of-Concept | 2019 |
| 119 | Kinaddict | Vulnerability of esophageal cancer to their addiction to kinase activities: evaluation and prediction of eSCC tumors responsiveness to kinase inhibitors. | 2019 |
| 120 | BrEXo-Apt | Non-invasive and accurate diagnosis and treatment of breast cancer. | 2019 |
| 121 | deCrYPtion | Decrypting Mycobacterium cytochrome P450 (CYP) physiological functions by testing hypotheses emitted form large-scale comparative genomics analysis | 2019 |
| 122 | anti-CRISPR | Selection and evolution of phage-encoded anti-CRISPR genes | 2019 |
| 123 | AR-DDR | Co-targeting androgen receptor signalling and DNA damage repair for precision therapy in advanced prostate cancer | 2019 |
| 124 | BICE | Circuit mechanisms for behavioral choice from complete CNS activity and connectivity maps | 2019 |
| 125 | IDEAL | Inhibitor of DUX4-IGH to Erase Acute lymphoblastic Leukaemia | 2020 |
| 126 | MAHT-FunSST | Microfluidic Approaches for High-Throughput Fungicide Screening and Sensitivity Testing | 2019 |
| 127 | 3D NKCC1 | Interdisciplinary approach to characterize the structure and the ion transport mechanism of NKCC1, a key target for brain disorders. | 2019 |
| 128 | RegulatioNFkB | Deciphering transcriptional regulation of NF-kB target genes using integrative omics approaches | 2019 |
| 129 | NumBraInf | The Role of Prefrontal Cortex in Functional Brain Organization of Number Processing in Infants | 2019 |
| 130 | IBL-302 | Inflection Bioscience unique dual mechanism, small molecule, orally available therapeutic targeting major unmet medical needs in breast cancer | 2019 |
| 131 | SynProAtCell | Delivery and On-Demand Activation of Chemically Synthesized and Uniquely Modified Proteins in Living Cells | 2019 |
| 132 | EPICAN | Inhibiting tumor cell plasticity by targeting the epigenome in breast cancer | 2020 |
| 133 | ECOEXTENDER | An alternative to antibiotics in porcine semen doses | 2019 |
| 134 | UNPACK PD-L1 | Molecular mechanism and inhibition of extracellular vesicle-mediated PD-L1 release in melanoma cells | 2020 |
| 135 | RASImmune | Targeting RAS driven tumour immune evasion | 2019 |
| 136 | INJURMET | Impact of tissue injury induced by diagnostic biopsies and surgery on cancer metastasis | 2019 |
| 137 | Angio-NYT | Investigating the crosstalk between Notch and YAP/TAZ in sprouting angiogenesis | 2020 |
| 138 | CONNECT-2-CLINIC | Pannexin1 nanobodies for the clinical treatment of liver disease | 2020 |
| 139 | TRACER | TRAF-STOP therapy to reduCe inflammation in athERosclerosis. | 2020 |
| 140 | SMARTINCS | Self-healing, Multifunctional, Advanced Repair Technologies IN Cementitious Systems | 2019 |
| 141 | MYCure | Innovative cancer therapy through Myc inhibition: taking OMO-103 to market | 2019 |
| 142 | CYPNASH | Validation of a novel class of cyclophilin inhibitors for the treatment of non-alcoholic steatohepatitis | 2019 |
| 143 | CHANCE | Structure guided inhibition of IDOL to treat atherosclerosis and the metabolic syndrome | 2019 |
| 144 | CSI AurkA-MYC | Conformational Shift Inducers (CSI): An atomistic level investigation of Aurora kinase A (AurkA)–MYC interaction and its distortion by CSI compounds | 2019 |
| 145 | ONco-Energetics_OFF | Dissection of Bioenergetic Plasticity of Tumors | 2020 |
| 146 | CANDY | Comorbid Analysis of Neurodevelopmental Disorders and Epilepsy | 2020 |
| 147 | PARPinhibit | A systems biology approach to tackle PARP-inhibitors resistance and identify novel therapeutic targets to overcome it | 2020 |
| 148 | PANACHE | Production of next generation modulators of pannexins and connexins as novel therapeutics in the treatment of inflammatory cardiovascular, hepatic and joint diseases. | 2020 |
| 149 | inhibiTOR | Novel selective mTORC1 inhibitors | 2020 |
| 150 | Glue2Degrade | Therapeutic hijacking of E3 Ligases | 2020 |
| 151 | PHYRIST | Physiological roles of the Ribotoxic Stress Response | 2020 |
| 152 | TrojanDC | Harnessing dendritic cell reprogramming for cancer immunotherapy | 2020 |
| 153 | SweetVision | Envisioning the Reward: Neuronal circuits for goal-directed learning | 2020 |
| 154 | RECOBIN-PROTACs | Reversible Covalently Binding PROTACs Technology for Protein Degradation in Cancer Therapy | 2020 |
| 155 | TESTIMONY | Tumor Endothelial Cells: Gatekeepers Of Anti-Tumor Immunity | 2020 |
| 156 | SERWOM | Understanding Serotonergic Regulation of Working Memory | 2020 |
| 157 | MotiVTA | Characterizing opposing BNST to VTA circuits that differentially regulate motivation and individual responses to stress | 2020 |
| 158 | DEAllAct | Dissecting and Engineering Allosteric Activation in a Biosynthetic Enzyme | 2020 |
| 159 | GlioTarget | Inflaming the microenvironment of glioblastoma tumors by ADAR1 inhibition: a two-hit approach for the treatment of brain cancer. | 2021 |
| 160 | NANOCRISPR | NANODELIVERY OF SPECIFIC GENOME ENGINEERING TOOLS AS A NOVEL THERAPEUTIC APPROACH FOR AGGRESSIVE PROSTATE CANCERS | 2021 |
| 161 | CCMuPWA | Characterize corpus callosum-mediated local and global inhibitory effects with novel MRI-compatible photonic crystal fiber-based multifunction probe and wireless amplified NMR detector in rat brain | 2020 |
| 162 | RegARcis | Role of the SWI/SNF complex in the Androgen Receptor cistrome regulation | 2020 |
| 163 | RCC_Evo | Modelling the Predictability and Repeatability of Tumour Evolution in Clear Cell Renal Cell Cancer | 2020 |