The page lists 163 projects related to the topic "inhibition".
|Conservative iron chelation as a disease-modifying strategy in Parkinson’s disease: a multicentric, parallel-group, placebo-controlled, randomized clinical trial of deferiprone
|REgeneration of inner ear hair cells with GAmma-secretase INhibitors to regain hearing in patients with sensorineural hearing loss
|Development of pregnenolone derivatives as allosteric inhibitors of CB1 cannabinoid receptors for the treatment of schizophrenia and psychotic syndromes
|Functions of non-coding RNAs in protein synthesis and homeostasis during aging
|Isoform specific inhibition by transient protein state stabilization
|New Approaches to Metallo-β-Lactamase Inhibitors
|Development of Palladium-Labile Prodrugs for Bioorthogonally-Activated Chemotherapy
|Surfactant controlled Cation Exchange Lithography - Towards Application
|Identification and characterization of novel essential regulators of acute myeloid leukemia
|Role of the sorting receptor SorCS1 in controlling excitation/inhibition balance in neural circuits.
|Optopharmacological brain mapping of autism mouse models
|Integrated study of the role of B-cell receptor signaling in the development of Follicular Lymphoma
|Accelerating metal-directed assembly, recognition and catalysis with computational methods
|Antifreeze GlycoProtein Mimetic Polymers
|DDRNA-based cancer therapy targeted telomeres
|Stromal cells as primary drivers of immunopathology: towards targeted disease modification in spondyloarthritis
|Personalized Nanomedicines for Leukemia Patients
|Formation and Characterization of Protein Post-Translational Modifications and Assessment of Cellular Responses by Application of Metals in Biological Systems
|Transdiagnostic views on eating disorders and obesity and new approaches for treatment
|The Evolutionary and Developmental Origins of Inquiring Minds: Studies of Causal Reasoning; Curiosity and Executive Control
|Homeostatic balancing of excitation and inhibition in vivo
|The Unfolded Protein Response in Neurodegeneration
|Reactions That Translate mRNA into Drug-like Molecules
|New breast cancer therapies based on available p38 MAPK inhibitors
|The psychology and neurobiology of cognitive control training in humans
|Discovery of Bcl-3 inhibitors as Potential Chemopreventive Agent for skin cancer
|Theranostic Injectable Hydrogel for Glioblastoma
|Overcoming the epigenetic and therapeutic barrier of EVI1-overexpressing cancers
|Cellular substrate of abnormal network maturation in neuropsychiatric disorders
|Targeting TGF-β activation, likely the core mechanism of immunosuppression by human regulatory T cells.
|Large-scale cortical communication: Brain oscillatory mechanisms of attention allocation and selective inhibition
|Modelling the therapeutic potential of NUAK1 suppression in colorectal cancer
|Bilingual inhibitory control: N-2 language repetition costs unchained
|MRCKa in cancer
|Targeting Cancer Cell Invasion and Metastasis by Inhibition of the Serine Kinase MRCKa
|Therapeutic and Biomarker Potential of long non-coding RNAs in Vascular Disease
|Targeting common oncogenes with intracellular monobodies
|Cell-type Specific Mechanisms and Functional Consequences of Altered NMDA Receptor Development and Mecp2 Deficiency on Developing Cortical Circuits
|Dynamic responsive porous crystals
|Brain stimulation of attention networks: examining old principles and developing new clinical applications
|In vivo pharmacogenetic investigation of 5-HT mechanisms in emotional learning
|Dissecting the cellular mechanics of contact inhibition of locomotion
|Take control!Towards novel training regimes enhancing inhibition and impulse control in health and psychiatric disease
|Pleiotropic treatment of cancer: RANK inhibitors targeting cancer stem cells and immunity
|Cell-specific vascular protection by CXCL12/CXCR4
|Developing an anti-Myc cell-penetrating peptide for cancer treatment
|Leveraging Small Demethylase inhibitors for Autism Spectrum Disorder
|Deciphering the machinery involved in stability of the transcription factor HOXA9.
|Multidisciplinary European training network for development of personalized anti-infective medical devices combining printing technologies and antimicrobial functionality
|Exploration and promotion of neurogenesis in the adult brain
|Computational Design of Novel Functional Proteins for Immunoengineering
|Blocking Inhibition of T-cell Co-stimulation for Anti-tumour Therapy
|New siRNA Nanotherapy for Inflammatory Bowel Diseases, targeting Janus kinases
|CD40 goes innate: defining and targeting CD40 signaling intermediates in the macrophage to treat atherosclerosis
|Dis-inhibitory circuits in the human cerebral cortex
|Optical Interrogation of Hippocampal Dentate Granule Circuit Dynamics in Health and Disease
|Photosynthesis in PHYTOplankton Mixtures to Investigate Community Structuration.
|Visual and vestibular processing in secondary visual cortex
|Novel, highly effective and selective anticancer metallodrugs
|Targeting CRISPR-based HDAC inhibitors to histones: a new tool for assessing mechanisms of class I HDAC inhibitors and developing chemical probes.
|Scaffold hybridization approach targeting PPIs
|Cognition, ageing, and bilingualism: Investigating age-related changes in bilingual language switching and use.
|Generation of new zebrafish models for the study of the pathogenesis of Huntington´s disease and for the identification of new therapeutic targets.
|RAS/C-RAF interaction: A new pharmacological target in Kras-driven lung cancer.
|Novel strategies for anti-HIV-1 therapy: Small molecules targeting RNA partners of the nucleocapsid protein
|An Integrated Computational and Experimental Approach to Rapid Synthesis of Highly Selective Dual-Targeted HDAC/CK2, MMP2/CK2 Inhibitors
|VWF and NETs
|Investigating the interplay between VWF, platelets, and neutrophil extracellular traps in pathologies involving thrombosis of the microvasculature
|The ATP-P2X7R axis: a target for drug-refractory epilepsy
|Extra-gonadal roles of Anti-Müllerian Hormone in the aetiology of polycystic ovary syndrome: the domino effect to reproductive neuroendocrine dysfunctions
|Control of amyloid formation via beta-hairpin molecular recognition features
|Neurocognitive mechanisms of inhibitory control training and transfer effects in children
|Assessing compounds targeting DNA replication licensing complexes as anti-tumor agents
|Telomere metabolism in Genome Stability and Disease
|Targeting the Oncogenic Function of Myc in vivo
|Preclinical concept validation of tumor endothelial cell metabolism for novel anti-angiogenic therapy
|Surviving salinity: How do plants sense Na+?
|Nitric oxide regulation of repolarisation in the heart: role of mechanical stress
|Ultrafast photonics for the detection and recognition of toxic spine-structures of amyloid aggregates linked to neurodegenerative disease
|Ceramide Synthases in Diabetic Beta Cell Demise
|Biological routes for CO2 conversion into chemical building blocks
|Innovative materials and techniques for the conservation of 20th century concrete-based cultural heritage
|BOOSTing the industrial application of green carbides by thermal spraying in protective coatings
|Defective protein translation as a pathogenic mechanism of peripheral neuropathy
|Harnessing clonal evolution in chronic lymphocytic leukemia
|What is the role of the axonal connections between the hemispheres in sensory processing?
|Synthetic toolkit for fragment oriented synthesis
|Understanding decision making by linking brain and behaviour
|Dissecting Multivalent Viral Receptor-carbohydrate Interactions Using Polyvalent Multifunctional Glycan-Quantum Dot
|Smart anticorrosion coatings based on nanocontainers loaded with novel, eco-friendly cationic gemini surfactants as efficient corrosion inhibitors for carbon steel in seawater.
|Novel Metabolic Pathways in Cancer
|Role of GABAergic interneurons in the formation of new memory traces in the Dentate Gyrus ofbehaving mice
|Non-linear temporal dynamics of mutually inhibiting pyramidal cells: underlying mechanism for bi-stable perception and disambiguation
|Using antisense inhibition to understand Wolbachia symbiosis and antiviral protection
|Virus-induced autophagy restriction
|Nanoparticles with switchable shells for virus sensing and inhibition
|A novel immunotherapy against brain metastasis: Anti-Galectin-3
|Dissecting the functional pathways of B cell receptor immunoglobulin in antigen driven mature B cell lymphomas
|Fine-tuning the brain’s brakes – modulating inhibitory control with transcranial alternating current stimulation
|Complement: to clear or not to clear
|Structural sudies of the bacterial lipid rafts.
|Role of mTOR signaling dysregulation in the tumor suppressor networks in hepatocellular carcinoma
|Dietary Influences on Metastasis: How, When, and Why
|Pro-tumorigenic effects of TGFb - elucidation of mechanisms and development of selective inhibitors
|Senescence therapy for cancer
|3D Organization of Functionally Conserved Cis-Regulatory Elements
|A New Adjuvant Nutraceutical from the North Atlantic Ocean for Breast, Lung and Pancreatic Cancer Patients
|Development of an effective and safe systemic Myc inhibitor for the treatment of multiple cancer types.
|The wide-spread bacterial toxin delivery systems and their role in multicellularity
|Robust and Efficient processes and technologies for Drop In renewable FUELs for road transport
|Searching for novel strategies improving cancer immunotherapy
|Innovative therapeutic tools to ameliorate chemotherapy-induced cardiotoxicity
|Translation and Commercialization of a QSOX1-inhibitory Antibody Targeting the Tumor Microenvironment in Breast Cancer
|Assays for the identification of Thyroid Hormone axis-disrupting chemicals: Elaborating Novel Assessment strategies
|Bacteriophage inhibition of antibiotic-resistant pathogenic microbes and founding for novel therapeutic strategies
|Imaging Biomolecular Self-Assembly with a Molecular Photonic Scale
|An integrated hypothesis for cognitive and positive symptoms in schizophrenia
|Establishing the molecular fundamentals of arthritic diseases – a step forward to Heal Arthritis
|INNOVATIVE GROUND INTERFACE CONCEPTS FOR STRUCTURE PROTECTION
|Psychiatric Disorders: ATX-inhibiting drugs as a new therapeutic option: Proof-of-Concept
|Vulnerability of esophageal cancer to their addiction to kinase activities: evaluation and prediction of eSCC tumors responsiveness to kinase inhibitors.
|Non-invasive and accurate diagnosis and treatment of breast cancer.
|Decrypting Mycobacterium cytochrome P450 (CYP) physiological functions by testing hypotheses emitted form large-scale comparative genomics analysis
|Selection and evolution of phage-encoded anti-CRISPR genes
|Co-targeting androgen receptor signalling and DNA damage repair for precision therapy in advanced prostate cancer
|Circuit mechanisms for behavioral choice from complete CNS activity and connectivity maps
|Inhibitor of DUX4-IGH to Erase Acute lymphoblastic Leukaemia
|Microfluidic Approaches for High-Throughput Fungicide Screening and Sensitivity Testing
|Interdisciplinary approach to characterize the structure and the ion transport mechanism of NKCC1, a key target for brain disorders.
|Deciphering transcriptional regulation of NF-kB target genes using integrative omics approaches
|The Role of Prefrontal Cortex in Functional Brain Organization of Number Processing in Infants
|Inflection Bioscience unique dual mechanism, small molecule, orally available therapeutic targeting major unmet medical needs in breast cancer
|Delivery and On-Demand Activation of Chemically Synthesized and Uniquely Modified Proteins in Living Cells
|Inhibiting tumor cell plasticity by targeting the epigenome in breast cancer
|An alternative to antibiotics in porcine semen doses
|Molecular mechanism and inhibition of extracellular vesicle-mediated PD-L1 release in melanoma cells
|Targeting RAS driven tumour immune evasion
|Impact of tissue injury induced by diagnostic biopsies and surgery on cancer metastasis
|Investigating the crosstalk between Notch and YAP/TAZ in sprouting angiogenesis
|Pannexin1 nanobodies for the clinical treatment of liver disease
|TRAF-STOP therapy to reduCe inflammation in athERosclerosis.
|Self-healing, Multifunctional, Advanced Repair Technologies IN Cementitious Systems
|Innovative cancer therapy through Myc inhibition: taking OMO-103 to market
|Validation of a novel class of cyclophilin inhibitors for the treatment of non-alcoholic steatohepatitis
|Structure guided inhibition of IDOL to treat atherosclerosis and the metabolic syndrome
|Conformational Shift Inducers (CSI): An atomistic level investigation of Aurora kinase A (AurkA)–MYC interaction and its distortion by CSI compounds
|Dissection of Bioenergetic Plasticity of Tumors
|Comorbid Analysis of Neurodevelopmental Disorders and Epilepsy
|A systems biology approach to tackle PARP-inhibitors resistance and identify novel therapeutic targets to overcome it
|Production of next generation modulators of pannexins and connexins as novel therapeutics in the treatment of inflammatory cardiovascular, hepatic and joint diseases.
|Novel selective mTORC1 inhibitors
|Therapeutic hijacking of E3 Ligases
|Physiological roles of the Ribotoxic Stress Response
|Harnessing dendritic cell reprogramming for cancer immunotherapy
|Envisioning the Reward: Neuronal circuits for goal-directed learning
|Reversible Covalently Binding PROTACs Technology for Protein Degradation in Cancer Therapy
|Tumor Endothelial Cells: Gatekeepers Of Anti-Tumor Immunity
|Understanding Serotonergic Regulation of Working Memory
|Characterizing opposing BNST to VTA circuits that differentially regulate motivation and individual responses to stress
|Dissecting and Engineering Allosteric Activation in a Biosynthetic Enzyme
|Inflaming the microenvironment of glioblastoma tumors by ADAR1 inhibition: a two-hit approach for the treatment of brain cancer.
|NANODELIVERY OF SPECIFIC GENOME ENGINEERING TOOLS AS A NOVEL THERAPEUTIC APPROACH FOR AGGRESSIVE PROSTATE CANCERS
|Characterize corpus callosum-mediated local and global inhibitory effects with novel MRI-compatible photonic crystal fiber-based multifunction probe and wireless amplified NMR detector in rat brain
|Role of the SWI/SNF complex in the Androgen Receptor cistrome regulation
|Modelling the Predictability and Repeatability of Tumour Evolution in Clear Cell Renal Cell Cancer