Explore the words cloud of the REMATCH project. It provides you a very rough idea of what is the project "REMATCH" about.
The following table provides information about the project.
DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG
|Coordinator Country||Germany [DE]|
|Total cost||149˙500 €|
|EC max contribution||149˙500 € (100%)|
1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
|Duration (year-month-day)||from 2018-08-01 to 2020-01-31|
Take a look of project's partnership.
|1||DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG||DE (HEIDELBERG)||coordinator||149˙500.00|
Drug discovery and development has become a lengthy and resource-intensive process which is characterized by high attrition rates of candidate molecules. Candidate molecules are often identified in high-throughput screening experiments that capture only a small fraction of its biological activities and too many candidates fail in clinical development due to unwanted side-effects and lack of a therapeutic window. In addition, many approved drugs harbor unrecognized therapeutic efficacy in other indications that were not covered during development. Necessary deep characterization of candidate molecules during pre-clinical development demands further efficient and cost-effective methods and data rich assays. Providing a solution to compare phenotypic measurements to a reference database can facilitate the profiling of unwanted effects and the identification of drugs with potential for repurposing. High-content imaging provides a cost-effective solution to capture a broad range of biological responses, however, analysis of such data requires extensive expertise and data processing pipelines. This project has the following objectives: (i) to develop a cloud-based infrastructure for analyses of image-based drug screening (WP1), (ii) to perform a proof-of-concept screen to create a reference database and a showcase for commercialization (WP2), (iii) to conduct market analyses and development of a business plan for a spin-off company (WP3). The ERC Proof of Concept Grant will thus enable us, based on methods pioneered in our ERC Advanced Grant, to develop and perform a proof-of-concept as well as to develop an innovative knowledge base and cloud-IT product for drug development and repositioning.
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The information about "REMATCH" are provided by the European Opendata Portal: CORDIS opendata.