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EpiSyStem SIGNED

Epigenetics and System Biology of Stem cells and Reprogramming

Total Cost €

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EC-Contrib. €

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Partnership

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Project "EpiSyStem" data sheet

The following table provides information about the project.

Coordinator
THE HEBREW UNIVERSITY OF JERUSALEM 

Organization address
address: EDMOND J SAFRA CAMPUS GIVAT RAM
city: JERUSALEM
postcode: 91904
website: www.huji.ac.il

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Israel [IL]
 Total cost 3˙598˙191 €
 EC max contribution 3˙598˙191 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2017
 Funding Scheme MSCA-ITN-ETN
 Starting year 2018
 Duration (year-month-day) from 2018-03-01   to  2022-02-28

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    THE HEBREW UNIVERSITY OF JERUSALEM IL (JERUSALEM) coordinator 780˙901.00
2    INSTITUT CURIE FR (PARIS) participant 525˙751.00
3    UNIVERSITA DEGLI STUDI DI MILANO IT (MILANO) participant 516˙122.00
4    KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW NL (AMSTERDAM) participant 510˙748.00
5    HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH DE (NEUHERBERG) participant 498˙432.00
6    KADIMASTEM LTD IL (NES ZIONA) participant 260˙300.00
7    STICHTING KATHOLIEKE UNIVERSITEIT NL (NIJMEGEN) participant 255˙374.00
8    DIAGENODE BE (SERAING) participant 250˙560.00

Map

 Project objective

Chromatin is the basic regulatory unit of life, and as such it controls developmental and functional states of all cells, including pluripotency. In recent years methods to study chromatin and transcription have dramatically improved and expanded to genome-wide global approaches on the one hand, and single cell biology on the other, allowing systems-level understanding of epigenetic regulation of stem cells, reprogramming and development. The Epigenetics and Systems Biology of Stem Cells and Reprogramming Network (EpiSyStem) is comprised of 8 world renowned, ERC-granted researchers, 2 professional leading industrial partners and supported by 3 partner organizations and 3 international world acclaimed scientists as an advisory board, to provide a unique training environment. EpiSyStem combines chromatin biology in stem cells, early embryos and reprogramming, including the modelling of human neurological, chromatin-related diseases with bioinformatics, epigenetics/epigenomics, and systems biology at the population and single cell / single embryo level. This multidisciplinary approach will enable profound training and deep, systems-level understanding of chromatin biology and epigenetic regulation of stem cells, differentiation and reprogramming, with a strong support by industrial partners. The objectives of EpiSyStem is to create a European mesh in which 14 outstanding PhD students will be trained in fundamental questions of biological research, be exposed to the latest technologies and breakthroughs, supervised by leading experts with international contacts - with the aim to facilitate their path to future leadership with holistic view, coupled with the forefront of the current epigenetic research in the field. They will enjoy exchange programs, workshops on emerging topics in stem cell epigenetics and bioinformatics, international conferences and meetings, and will communicate their findings to the scientific community as well as the general public.

 Publications

year authors and title journal last update
List of publications.
2019 Matteo Zanella, Alessandro Vitriolo, Alejandro Andirko, Pedro Tiago Martins, Stefanie Sturm, Thomas O’Rourke, Magdalena Laugsch, Natascia Malerba, Adrianos Skaros, Sebastiano Trattaro, Pierre-Luc Germain, Marija Mihailovic, Giuseppe Merla, Alvaro Rada-Iglesias, Cedric Boeckx, Giuseppe Testa
Dosage analysis of the 7q11.23 Williams region identifies BAZ1B as a major human gene patterning the modern human face and underlying self-domestication
published pages: eaaw7908, ISSN: 2375-2548, DOI: 10.1126/sciadv.aaw7908
Science Advances 5/12 2020-04-11

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The information about "EPISYSTEM" are provided by the European Opendata Portal: CORDIS opendata.

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