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MultiphysMicroCaps SIGNED

Multiphysics study of the dynamics, resistance and targeted therapy potential of deformable Micro-Capsules

Total Cost €

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EC-Contrib. €

0

Partnership

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 MultiphysMicroCaps project word cloud

Explore the words cloud of the MultiphysMicroCaps project. It provides you a very rough idea of what is the project "MultiphysMicroCaps" about.

storage    optimization    optimal    antioxidant    numerical    techniques    active    protect    source    introduce    time    biotechnologies    predict    core    outcomes    wall    industry    tech    liquid    simulations    characterizing    size    medium    environment    antioxidants    semi    elastic    structure    capsule    engineering    biomedical    enclosing    hydrodynamic    health    rupture    payload    scientific    protection    internal    deformability    dimensional    first    thickness    tools    fluid    models    microcapsules    pharmacology    industrial    optimize    membrane    substances    innovative    populations    inherent    vectors    transport    finite    micrometric    tremendous    explores    effect    enrichment    dynamics    permeable    world    experiments    variability    solid    mechanical    deformable    consists    compromise    capsules    food    sophisticated    microscopic    microfluidic    interactions    resistance    encapsulation    material    breakup    stresses    encapsulate    primary    microcapsule    moment    energy    met   

Project "MultiphysMicroCaps" data sheet

The following table provides information about the project.

Coordinator
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS 

Organization address
address: RUE MICHEL ANGE 3
city: PARIS
postcode: 75794
website: www.cnrs.fr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Total cost 1˙999˙470 €
 EC max contribution 1˙999˙470 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2017-COG
 Funding Scheme ERC-COG
 Starting year 2018
 Duration (year-month-day) from 2018-06-01   to  2023-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS FR (PARIS) coordinator 1˙999˙470.00

Map

 Project objective

Encapsulation consists in enclosing an internal medium in a solid semi-permeable membrane to protect it and control the exchanges with the environment. Being at the source of innovative applications in the fields of biotechnologies, pharmacology, energy storage and food industry, capsules offer tremendous potential in the process engineering world. But scientific challenges remain to be met, such as finding the optimal compromise between payload and membrane thickness, characterizing the membrane resistance and controlling the moment of rupture. The project explores the use of deformable liquid-core capsules of micrometric size to efficiently transport active material, with a primary focus on health-related applications. We will design innovative sophisticated numerical models and high-tech experiments, needed to determine the potential of such vectors for the protection of active substances, predict membrane breakup to control the delivery, and optimize their properties for specific industrial and biomedical applications. The project will, for the first time, study the effect of a finite wall thickness on the dynamics of elastic microcapsules, propose advanced modelling approaches and microfluidic experiments of their deformability and breakup under hydrodynamic stresses, account for the inherent size variability of given capsule populations, and introduce reduced-order models to facilitate real-time simulations. As a specific application, we will study the potential of liquid-core microcapsules to encapsulate antioxidants for food enrichment. The project outcomes will be (i) new advanced three-dimensional numerical models of the fluid-structure interactions and rupture of a microcapsule, taking into account a finite wall thickness, (ii) microcapsule optimization tools based on reduced-order models, (iii) microscopic techniques to measure the capsule mechanical properties, and (iv) an applied study of optimization of antioxidant encapsulation in microcapsules.

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The information about "MULTIPHYSMICROCAPS" are provided by the European Opendata Portal: CORDIS opendata.

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