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MultiphysMicroCaps SIGNED

Multiphysics study of the dynamics, resistance and targeted therapy potential of deformable Micro-Capsules

Total Cost €

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EC-Contrib. €

0

Partnership

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 MultiphysMicroCaps project word cloud

Explore the words cloud of the MultiphysMicroCaps project. It provides you a very rough idea of what is the project "MultiphysMicroCaps" about.

protection    microscopic    storage    consists    industrial    antioxidants    source    dimensional    vectors    techniques    experiments    solid    optimal    sophisticated    thickness    simulations    inherent    interactions    structure    characterizing    mechanical    innovative    deformable    protect    scientific    microcapsule    tech    models    enclosing    world    industry    biomedical    compromise    populations    liquid    active    engineering    health    size    outcomes    antioxidant    material    fluid    first    internal    tools    capsule    dynamics    explores    microfluidic    transport    payload    introduce    numerical    permeable    primary    optimize    substances    core    resistance    predict    optimization    food    micrometric    encapsulation    finite    energy    capsules    wall    tremendous    biotechnologies    pharmacology    membrane    moment    met    variability    stresses    effect    hydrodynamic    semi    elastic    deformability    time    enrichment    encapsulate    environment    microcapsules    rupture    breakup    medium   

Project "MultiphysMicroCaps" data sheet

The following table provides information about the project.

Coordinator
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS 

Organization address
address: RUE MICHEL ANGE 3
city: PARIS
postcode: 75794
website: www.cnrs.fr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Total cost 1˙999˙470 €
 EC max contribution 1˙999˙470 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2017-COG
 Funding Scheme ERC-COG
 Starting year 2018
 Duration (year-month-day) from 2018-06-01   to  2023-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS FR (PARIS) coordinator 1˙999˙470.00

Map

 Project objective

Encapsulation consists in enclosing an internal medium in a solid semi-permeable membrane to protect it and control the exchanges with the environment. Being at the source of innovative applications in the fields of biotechnologies, pharmacology, energy storage and food industry, capsules offer tremendous potential in the process engineering world. But scientific challenges remain to be met, such as finding the optimal compromise between payload and membrane thickness, characterizing the membrane resistance and controlling the moment of rupture. The project explores the use of deformable liquid-core capsules of micrometric size to efficiently transport active material, with a primary focus on health-related applications. We will design innovative sophisticated numerical models and high-tech experiments, needed to determine the potential of such vectors for the protection of active substances, predict membrane breakup to control the delivery, and optimize their properties for specific industrial and biomedical applications. The project will, for the first time, study the effect of a finite wall thickness on the dynamics of elastic microcapsules, propose advanced modelling approaches and microfluidic experiments of their deformability and breakup under hydrodynamic stresses, account for the inherent size variability of given capsule populations, and introduce reduced-order models to facilitate real-time simulations. As a specific application, we will study the potential of liquid-core microcapsules to encapsulate antioxidants for food enrichment. The project outcomes will be (i) new advanced three-dimensional numerical models of the fluid-structure interactions and rupture of a microcapsule, taking into account a finite wall thickness, (ii) microcapsule optimization tools based on reduced-order models, (iii) microscopic techniques to measure the capsule mechanical properties, and (iv) an applied study of optimization of antioxidant encapsulation in microcapsules.

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The information about "MULTIPHYSMICROCAPS" are provided by the European Opendata Portal: CORDIS opendata.

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