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MultiphysMicroCaps SIGNED

Multiphysics study of the dynamics, resistance and targeted therapy potential of deformable Micro-Capsules

Total Cost €

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EC-Contrib. €

0

Partnership

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 MultiphysMicroCaps project word cloud

Explore the words cloud of the MultiphysMicroCaps project. It provides you a very rough idea of what is the project "MultiphysMicroCaps" about.

optimization    effect    biotechnologies    pharmacology    simulations    payload    material    structure    capsule    microfluidic    breakup    mechanical    encapsulate    inherent    storage    fluid    micrometric    environment    microcapsule    enrichment    antioxidants    liquid    dynamics    rupture    predict    met    optimize    engineering    encapsulation    deformable    hydrodynamic    solid    first    health    dimensional    moment    resistance    techniques    energy    substances    stresses    scientific    tremendous    food    microcapsules    elastic    tools    permeable    vectors    internal    active    populations    experiments    variability    membrane    thickness    models    semi    industry    capsules    innovative    protect    wall    explores    protection    deformability    outcomes    optimal    primary    core    world    antioxidant    tech    compromise    interactions    biomedical    finite    consists    characterizing    industrial    sophisticated    enclosing    size    microscopic    medium    time    introduce    transport    source    numerical   

Project "MultiphysMicroCaps" data sheet

The following table provides information about the project.

Coordinator
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS 

Organization address
address: RUE MICHEL ANGE 3
city: PARIS
postcode: 75794
website: www.cnrs.fr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Total cost 1˙999˙470 €
 EC max contribution 1˙999˙470 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2017-COG
 Funding Scheme ERC-COG
 Starting year 2018
 Duration (year-month-day) from 2018-06-01   to  2023-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS FR (PARIS) coordinator 1˙999˙470.00

Map

 Project objective

Encapsulation consists in enclosing an internal medium in a solid semi-permeable membrane to protect it and control the exchanges with the environment. Being at the source of innovative applications in the fields of biotechnologies, pharmacology, energy storage and food industry, capsules offer tremendous potential in the process engineering world. But scientific challenges remain to be met, such as finding the optimal compromise between payload and membrane thickness, characterizing the membrane resistance and controlling the moment of rupture. The project explores the use of deformable liquid-core capsules of micrometric size to efficiently transport active material, with a primary focus on health-related applications. We will design innovative sophisticated numerical models and high-tech experiments, needed to determine the potential of such vectors for the protection of active substances, predict membrane breakup to control the delivery, and optimize their properties for specific industrial and biomedical applications. The project will, for the first time, study the effect of a finite wall thickness on the dynamics of elastic microcapsules, propose advanced modelling approaches and microfluidic experiments of their deformability and breakup under hydrodynamic stresses, account for the inherent size variability of given capsule populations, and introduce reduced-order models to facilitate real-time simulations. As a specific application, we will study the potential of liquid-core microcapsules to encapsulate antioxidants for food enrichment. The project outcomes will be (i) new advanced three-dimensional numerical models of the fluid-structure interactions and rupture of a microcapsule, taking into account a finite wall thickness, (ii) microcapsule optimization tools based on reduced-order models, (iii) microscopic techniques to measure the capsule mechanical properties, and (iv) an applied study of optimization of antioxidant encapsulation in microcapsules.

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The information about "MULTIPHYSMICROCAPS" are provided by the European Opendata Portal: CORDIS opendata.

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