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MultiphysMicroCaps SIGNED

Multiphysics study of the dynamics, resistance and targeted therapy potential of deformable Micro-Capsules

Total Cost €

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EC-Contrib. €

0

Partnership

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 MultiphysMicroCaps project word cloud

Explore the words cloud of the MultiphysMicroCaps project. It provides you a very rough idea of what is the project "MultiphysMicroCaps" about.

environment    interactions    vectors    size    food    encapsulate    resistance    elastic    industrial    permeable    biotechnologies    time    tools    enclosing    finite    payload    consists    first    membrane    rupture    explores    populations    microscopic    micrometric    microcapsule    introduce    engineering    substances    liquid    medium    dynamics    predict    deformability    thickness    optimization    antioxidant    sophisticated    storage    models    met    innovative    numerical    protection    inherent    active    optimize    material    deformable    primary    dimensional    pharmacology    mechanical    internal    experiments    industry    health    outcomes    tremendous    effect    stresses    tech    microcapsules    breakup    protect    fluid    solid    compromise    enrichment    encapsulation    characterizing    scientific    optimal    hydrodynamic    world    biomedical    capsule    energy    simulations    core    techniques    source    antioxidants    transport    semi    structure    capsules    variability    microfluidic    moment    wall   

Project "MultiphysMicroCaps" data sheet

The following table provides information about the project.

Coordinator
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS 

Organization address
address: RUE MICHEL ANGE 3
city: PARIS
postcode: 75794
website: www.cnrs.fr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Total cost 1˙999˙470 €
 EC max contribution 1˙999˙470 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2017-COG
 Funding Scheme ERC-COG
 Starting year 2018
 Duration (year-month-day) from 2018-06-01   to  2023-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS FR (PARIS) coordinator 1˙999˙470.00

Map

 Project objective

Encapsulation consists in enclosing an internal medium in a solid semi-permeable membrane to protect it and control the exchanges with the environment. Being at the source of innovative applications in the fields of biotechnologies, pharmacology, energy storage and food industry, capsules offer tremendous potential in the process engineering world. But scientific challenges remain to be met, such as finding the optimal compromise between payload and membrane thickness, characterizing the membrane resistance and controlling the moment of rupture. The project explores the use of deformable liquid-core capsules of micrometric size to efficiently transport active material, with a primary focus on health-related applications. We will design innovative sophisticated numerical models and high-tech experiments, needed to determine the potential of such vectors for the protection of active substances, predict membrane breakup to control the delivery, and optimize their properties for specific industrial and biomedical applications. The project will, for the first time, study the effect of a finite wall thickness on the dynamics of elastic microcapsules, propose advanced modelling approaches and microfluidic experiments of their deformability and breakup under hydrodynamic stresses, account for the inherent size variability of given capsule populations, and introduce reduced-order models to facilitate real-time simulations. As a specific application, we will study the potential of liquid-core microcapsules to encapsulate antioxidants for food enrichment. The project outcomes will be (i) new advanced three-dimensional numerical models of the fluid-structure interactions and rupture of a microcapsule, taking into account a finite wall thickness, (ii) microcapsule optimization tools based on reduced-order models, (iii) microscopic techniques to measure the capsule mechanical properties, and (iv) an applied study of optimization of antioxidant encapsulation in microcapsules.

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The information about "MULTIPHYSMICROCAPS" are provided by the European Opendata Portal: CORDIS opendata.

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