Explore the words cloud of the HEIREC project. It provides you a very rough idea of what is the project "HEIREC" about.
The following table provides information about the project.
THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE
|Coordinator Country||United Kingdom [UK]|
|Total cost||150˙000 €|
|EC max contribution||150˙000 € (100%)|
1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
|Duration (year-month-day)||from 2018-04-01 to 2019-09-30|
Take a look of project's partnership.
|1||THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE||UK (CAMBRIDGE)||coordinator||150˙000.00|
The increasing demand for food, in the context of a changing climate and deteriorating environments, will be one of the major challenges facing society in the coming decades. However, as breeding a new crop variety currently takes on average 10 years, the predicted changes in food demand and climate are only several breeding cycles away. Meiotic recombination and crossover is a major tool used in crop breeding when diverse strains are hybridized in order to combine useful traits. Therefore, in the current climate of change, there is an urgent need to reduce the time needed to produce new crop varieties, and meiotic recombination is one target to achieve this. In my ERC Consolidator grant SynthHotSpot, we are investigating the molecular control of meiotic recombination using the model plant Arabidopsis. We have identified the gene HEI10, which encodes a conserved meiotic ubiquitin E3 ligase, as a major regulator of crossover numbers. Importantly, during this work we discovered that HEI10 is highly dosage-sensitive and introduction of additional copies of this gene more than doubled crossovers throughout the Arabidopsis chromosome arms. As HEI10 is conserved between plants, fungi and animals, this may provide a gene target to manipulate crossover numbers in diverse species. In light of the demands on breeding companies to develop new, high yielding crop varieties, HEIREC will fast-track the development of a new platform technology to increase recombination frequency during breeding, via introduction of additional HEI10 copies. Within HEIREC we will generate proof of concept data where we increase HEI10 copy number within bread wheat, in order to increase recombination and thereby accelerate crop improvement. Bread wheat is a major crop globally where recombination level limits strain improvement. Therefore, by increasing recombination frequency during breeding, HEIREC will accelerate the development of new crop varieties and contribute to ensuring food security.
|year||authors and title||journal||last update|
Emma J. Lawrence, Hongbo Gao, Andrew J. Tock, Christophe Lambing, Alexander R. Blackwell, Xiaoqi Feng, Ian R. Henderson
Natural Variation in TBP-ASSOCIATED FACTOR 4b Controls Meiotic Crossover and Germline Transcription in Arabidopsis
published pages: 2676-2686.e3, ISSN: 0960-9822, DOI: 10.1016/j.cub.2019.06.084
|Current Biology 29/16||2020-01-29|
HeÃ¯di Serra, Christophe Lambing, Catherine H. Griffin, Stephanie D. Topp, Divyashree C. Nageswaran, Charles J. Underwood, Piotr A. Ziolkowski, Mathilde SÃ©guÃ©la-Arnaud, Joiselle B. Fernandes, RaphaÃ«l Mercier, Ian R. Henderson
Massive crossover elevation via combination of HEI10 and recq4a recq4b during Arabidopsis meiosis
published pages: 2437-2442, ISSN: 0027-8424, DOI: 10.1073/pnas.1713071115
|Proceedings of the National Academy of Sciences 115/10||2020-01-29|
Joiselle B Fernandes, Piotr Wlodzimierz, Ian R Henderson
Meiotic recombination within plant centromeres
published pages: 26-35, ISSN: 1369-5266, DOI: 10.1016/j.pbi.2019.02.008
|Current Opinion in Plant Biology 48||2020-01-29|
Are you the coordinator (or a participant) of this project? Plaese send me more information about the "HEIREC" project.
For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.
Send me an email (email@example.com) and I put them in your project's page as son as possible.
Thanks. And then put a link of this page into your project's website.
The information about "HEIREC" are provided by the European Opendata Portal: CORDIS opendata.