Opendata, web and dolomites

MICROBE SIGNED

Metagenomic Investigation of Cow Reproductive Biology and Ecology

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 MICROBE project word cloud

Explore the words cloud of the MICROBE project. It provides you a very rough idea of what is the project "MICROBE" about.

sperm    completing    explore    scientist    respected    merit    disease    uterus    either    hosted    25    genotypes    reproductive    metagenome    cow    leadership    endometrium    goals    divergent    usually    inflammatory    interactions    examine    dysbiosis    fertility    scope    supervision    university    cotter    broaden    hypotheses    pathogens    vivo       usa    pregnant    butler    negative    mechanisms    transport    postdoctoral    functional    lining    pregnancy    receptive    stephen    biology    microbe    reintegrate    acquire    survival    transcriptome    low    embryo    expand    unknown    myself    bacteria    cows    rates    attributed    paul    teagasc    endometritis    position    dairy    dr    college    metagenomic    genomic    lonergan    ex    investigation    hypothesis    annually    disrupted    billion    secondment    validate    industries    microbes    oviduct    ireland    dublin    internationally    development    30    symbiosis    figure    skills    missouri    genetic    populate    culture    responsive    calving    mortality    uterine    independent    prof    interact    patrick    isolate    isolated    microbiome    tissue    ecology   

Project "MICROBE" data sheet

The following table provides information about the project.

Coordinator
TEAGASC - AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY 

Organization address
address: Oak Park
city: Carlow
postcode: R93
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Ireland [IE]
 Total cost 175˙866 €
 EC max contribution 175˙866 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-EF-RI
 Starting year 2018
 Duration (year-month-day) from 2018-05-28   to  2020-05-27

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    TEAGASC - AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY IE (Carlow) coordinator 175˙866.00

Map

 Project objective

Low rates of embryo survival can be attributed to endometritis, an inflammatory disease of the endometrium lining the uterus. The disease affects ~30% of cows, increases embryo mortality by 25%4, and costs the EU and USA dairy industries €2 billion annually. The endometrium and microbiome are usually in a state of symbiosis when the cow is either receptive to pregnancy or pregnant. This symbiosis is disrupted (dysbiosis) at calving when pathogens populate the uterus. Endometritis has long term negative effects on embryo survival, but the mechanisms of how endometrium-microbe interactions affect embryo survival are unknown. The goals of MICROBE: Metagenomic Investigation of Cow Reproductive Biology and Ecology (Figure) are to (1) establish myself as an independent, internationally respected scientist in reproductive biology; (2) reintegrate into a long-term research position in Ireland after completing postdoctoral research at the University of Missouri; and (3) acquire new technical skills to broaden the scope of my research, and to expand my leadership and project management capabilities. I will be hosted by Teagasc with supervision from Dr. Stephen Butler and Dr. Paul Cotter with a secondment at University College Dublin with Prof. Patrick Lonergan. I will explore whether the endometrium and microbiome interact to affect embryo survival by testing novel hypotheses. The research objectives are to (1) examine endometrium-microbe interactions at the level of the transcriptome and metagenome of dairy cows, and test the hypothesis that such interactions are responsive to genomic selection for fertility; (2) isolate and culture specific uterine microbes from two genotypes of dairy cows divergent in fertility; and (3) use ex-vivo tissue culture systems to validate novel functional mechanisms by which uterine bacteria isolated from cows divergent in genetic merit for fertility interact with the oviduct and endometrium during sperm transport and embryo development

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "MICROBE" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "MICROBE" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.3.2.)

POSPORI (2019)

Polymer Optical Sensors for Prolonged Overseeing the Robustness of civil Infrastructures

Read More  

ACES (2019)

Antarctic Cyclones: Expression in Sea Ice

Read More  

PRISME (2019)

PRogram for ISolation Manufacturing in Europe (PRISME)

Read More