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GRACE SIGNED

hiGh-Resolution imAging of the barrel CortEx through VSD and LFP recordings

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 GRACE project word cloud

Explore the words cloud of the GRACE project. It provides you a very rough idea of what is the project "GRACE" about.

performed    designed    chronic    simultaneous    neuroscience    cortical    relations    whisker    neural    manifest    optical    primary    cortex    plasticity    onto    innovative    voltage    neurophysiology    populations    dye    3d    microcircuits    brain    directed    cmos    dr    dual    coding    recordings    waves    transfer    resolution    excellent    sensitive    mechanisms    communication    action    thanks    neuronal    mapping    insights    propagating    form    transferred    close    lfp    oist    combining    stimulation    neuroprostheses    propagation    patterned    cranial    somatosensory    unipd    coordinated    basic    mapped    offers    architecture    probes    population    barrel    topographic    competences    once    okinawa    potentials    functional    organization    mediating    simultaneously    tissue    vivo    directional    kuhn    implantable    padova    window    imaging    signal    electrical    living    area    evoked    rodents    vsd    neocortex    sensory    bi    japan    local    scientific   

Project "GRACE" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITA DEGLI STUDI DI PADOVA 

Organization address
address: VIA 8 FEBBRAIO 2
city: PADOVA
postcode: 35122
website: www.unipd.it

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Italy [IT]
 Total cost 195˙728 €
 EC max contribution 195˙728 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-GF
 Starting year 2019
 Duration (year-month-day) from 2019-06-01   to  2021-08-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITA DEGLI STUDI DI PADOVA IT (PADOVA) coordinator 195˙728.00
2    OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION GAKO HOJIN JP (OKINAWA) partner 0.00

Map

 Project objective

The aim of this action is to develop an innovative and advanced dual approach to study the barrel cortex, combining Voltage Sensitive Dye (VSD) imaging and high-resolution electrical recordings. The barrel cortex in rodents is part of the primary somatosensory cortex and a well-known example of topographic mapping, where each whisker is mapped onto a specific cortical area, called a barrel. Thanks to its unique functional organization, this system offers excellent conditions to investigate neural mechanisms mediating sensory coding, processing and plasticity. Sensory-evoked activity in the neocortex is known to manifest in the form of propagating waves but up to now there are no studies directed towards a high-resolution mapping of these waves in the barrel cortex in vivo. Thanks to the chronic cranial window designed by Dr. Kuhn at OIST, VSD imaging will be performed simultaneously with high-resolution electrical mapping of Local Field Potentials (LFP) through CMOS-based implantable neural probes developed within an EU project coordinated by UNIPD. Once fully established, this dual method will be transferred to UNIPD and will allow the study of neuronal signal propagation through a 3D architecture in living tissue with simultaneous high-resolution optical and electrical recordings. This action will increase my competences in neurophysiology and promote a close collaboration and a two-way transfer of scientific knowledge between Padova and Okinawa, enhancing the scientific relations between the European Research Area and Japan. This project will contribute to the development of advanced neuroprostheses allowing a bi-directional communication with brain microcircuits through high-resolution LFP recordings and patterned electrical stimulation of neural populations. Moreover, the results of my research will have a strong impact on basic neuroscience of population coding, providing novel insights on the propagation of sensory information within the barrel cortex.

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The information about "GRACE" are provided by the European Opendata Portal: CORDIS opendata.

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