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Opendata, web and dolomites

GRACE SIGNED

hiGh-Resolution imAging of the barrel CortEx through VSD and LFP recordings

Total Cost €

EC-Contrib. €

Partnership

Views

GRACE project word cloud

Explore the words cloud of the GRACE project. It provides you a very rough idea of what is the project "GRACE" about.

resolution rodents simultaneously form excellent mapping kuhn insights tissue close primary neuroprostheses simultaneous dr transfer neuronal mediating functional architecture stimulation thanks area barrel window basic imaging neural somatosensory cmos optical innovative plasticity propagating potentials communication combining electrical populations performed voltage population brain cortex japan living action vsd chronic cranial implantable bi manifest designed neocortex neurophysiology cortical evoked sensitive lfp propagation topographic vivo coding sensory scientific 3d oist dual transferred once okinawa mechanisms signal patterned relations mapped waves onto dye coordinated unipd recordings directional whisker padova directed offers competences neuroscience local microcircuits organization probes

Project "GRACE" data sheet

The following table provides information about the project.

Coordinator	UNIVERSITA DEGLI STUDI DI PADOVA Organization address address: VIA 8 FEBBRAIO 2 city: PADOVA postcode: 35122 website: www.unipd.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Italy [IT]
Total cost	195˙728 €
EC max contribution	195˙728 € (100%)
Programme	1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
Code Call	H2020-MSCA-IF-2017
Funding Scheme	MSCA-IF-GF
Starting year	2019
Duration (year-month-day)	from 2019-06-01 to 2021-08-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	UNIVERSITA DEGLI STUDI DI PADOVA UNIVERSITA DEGLI STUDI DI PADOVA Organization address address: VIA 8 FEBBRAIO 2 city: PADOVA postcode: 35122 website: www.unipd.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (PADOVA)	coordinator	195˙728.00
2	OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION GAKO HOJIN OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION GAKO HOJIN Organization address address: TANCHA 1919 1 ONNA SON KUNIGAMI GUN city: OKINAWA postcode: 904 0495 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	JP (OKINAWA)	partner	0.00

Map

Project objective

The aim of this action is to develop an innovative and advanced dual approach to study the barrel cortex, combining Voltage Sensitive Dye (VSD) imaging and high-resolution electrical recordings. The barrel cortex in rodents is part of the primary somatosensory cortex and a well-known example of topographic mapping, where each whisker is mapped onto a specific cortical area, called a barrel. Thanks to its unique functional organization, this system offers excellent conditions to investigate neural mechanisms mediating sensory coding, processing and plasticity. Sensory-evoked activity in the neocortex is known to manifest in the form of propagating waves but up to now there are no studies directed towards a high-resolution mapping of these waves in the barrel cortex in vivo. Thanks to the chronic cranial window designed by Dr. Kuhn at OIST, VSD imaging will be performed simultaneously with high-resolution electrical mapping of Local Field Potentials (LFP) through CMOS-based implantable neural probes developed within an EU project coordinated by UNIPD. Once fully established, this dual method will be transferred to UNIPD and will allow the study of neuronal signal propagation through a 3D architecture in living tissue with simultaneous high-resolution optical and electrical recordings. This action will increase my competences in neurophysiology and promote a close collaboration and a two-way transfer of scientific knowledge between Padova and Okinawa, enhancing the scientific relations between the European Research Area and Japan. This project will contribute to the development of advanced neuroprostheses allowing a bi-directional communication with brain microcircuits through high-resolution LFP recordings and patterned electrical stimulation of neural populations. Moreover, the results of my research will have a strong impact on basic neuroscience of population coding, providing novel insights on the propagation of sensory information within the barrel cortex.

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The information about "GRACE" are provided by the European Opendata Portal: CORDIS opendata.