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GRACE SIGNED

hiGh-Resolution imAging of the barrel CortEx through VSD and LFP recordings

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

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 GRACE project word cloud

Explore the words cloud of the GRACE project. It provides you a very rough idea of what is the project "GRACE" about.

neural    neuroprostheses    cmos    chronic    mediating    form    simultaneous    tissue    area    japan    close    primary    barrel    propagating    padova    somatosensory    competences    basic    optical    onto    lfp    patterned    cortical    organization    dye    plasticity    relations    communication    transferred    directed    neocortex    mapping    mechanisms    microcircuits    imaging    insights    propagation    kuhn    3d    local    population    okinawa    vsd    dual    brain    scientific    potentials    resolution    populations    recordings    coding    neurophysiology    cranial    bi    coordinated    signal    manifest    mapped    neuronal    unipd    action    oist    stimulation    voltage    whisker    window    directional    waves    sensitive    sensory    functional    neuroscience    simultaneously    innovative    designed    electrical    transfer    implantable    dr    rodents    cortex    evoked    once    offers    excellent    vivo    topographic    living    probes    performed    combining    thanks    architecture   

Project "GRACE" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITA DEGLI STUDI DI PADOVA 

Organization address
address: VIA 8 FEBBRAIO 2
city: PADOVA
postcode: 35122
website: www.unipd.it

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Italy [IT]
 Total cost 195˙728 €
 EC max contribution 195˙728 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-GF
 Starting year 2019
 Duration (year-month-day) from 2019-06-01   to  2021-08-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITA DEGLI STUDI DI PADOVA IT (PADOVA) coordinator 195˙728.00
2    OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION GAKO HOJIN JP (OKINAWA) partner 0.00

Map

 Project objective

The aim of this action is to develop an innovative and advanced dual approach to study the barrel cortex, combining Voltage Sensitive Dye (VSD) imaging and high-resolution electrical recordings. The barrel cortex in rodents is part of the primary somatosensory cortex and a well-known example of topographic mapping, where each whisker is mapped onto a specific cortical area, called a barrel. Thanks to its unique functional organization, this system offers excellent conditions to investigate neural mechanisms mediating sensory coding, processing and plasticity. Sensory-evoked activity in the neocortex is known to manifest in the form of propagating waves but up to now there are no studies directed towards a high-resolution mapping of these waves in the barrel cortex in vivo. Thanks to the chronic cranial window designed by Dr. Kuhn at OIST, VSD imaging will be performed simultaneously with high-resolution electrical mapping of Local Field Potentials (LFP) through CMOS-based implantable neural probes developed within an EU project coordinated by UNIPD. Once fully established, this dual method will be transferred to UNIPD and will allow the study of neuronal signal propagation through a 3D architecture in living tissue with simultaneous high-resolution optical and electrical recordings. This action will increase my competences in neurophysiology and promote a close collaboration and a two-way transfer of scientific knowledge between Padova and Okinawa, enhancing the scientific relations between the European Research Area and Japan. This project will contribute to the development of advanced neuroprostheses allowing a bi-directional communication with brain microcircuits through high-resolution LFP recordings and patterned electrical stimulation of neural populations. Moreover, the results of my research will have a strong impact on basic neuroscience of population coding, providing novel insights on the propagation of sensory information within the barrel cortex.

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The information about "GRACE" are provided by the European Opendata Portal: CORDIS opendata.

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