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EvoConBiO SIGNED

Uncovering and engineering the principles governing evolution and cellular control of bioenergetic organelles

Total Cost €

0

EC-Contrib. €

0

Partnership

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 EvoConBiO project word cloud

Explore the words cloud of the EvoConBiO project. It provides you a very rough idea of what is the project "EvoConBiO" about.

experiment    manipulation    sky    strategies    drive    algae    direction    cells    reward    bioenergetic    independent    genomes    nucleus    chloroplast    powered    maintenance    combination    experimental    resolve    mtdna    earth    evolutionary    suggests    mathematical    organelle    evoconbio    first    risk    tension    cutting    genes    universal    populations    plants    genetic    time    robustness    statistics    dramatically    groundbreaking    retaining    ecosystem    maintaining    life    underlying    organisms    engineer    reveal    agriculture    scientific    questions    modern    shaping    poorly    cellular    rational    uncovering    central    form    content    integrity    history    edge    insights    evolution    cpdna    blue    retained    akin    theory    biofuel    characterisation    mitochondria    individuals    organelles    interdisciplinary    bioengineering    performance    dynamic    transferring    structure    combining    day    eukaryotic    harness    principles    adapt    chloroplasts    originally    points    co    unprecedented   

Project "EvoConBiO" data sheet

The following table provides information about the project.

Coordinator		 UNIVERSITETET I BERGEN 

Organization address
address: MUSEPLASSEN 1
city: BERGEN
postcode: 5020
website: www.uib.no

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.
 Coordinator Country Norway [NO]
 Total cost 1˙417˙862 €
 EC max contribution 1˙417˙862 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2018-STG
 Funding Scheme ERC-STG
 Starting year 2019
 Duration (year-month-day) from 2019-07-01   to  2024-06-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITETET I BERGEN NO (BERGEN) coordinator 1˙417˙862.00
2    THE UNIVERSITY OF BIRMINGHAM UK (BIRMINGHAM) participant 0.00

Map

 Project objective

'Complex life on Earth is powered by bioenergetic organelles -- mitochondria and chloroplasts. Originally independent organisms, these organelles have retained their own genomes (mtDNA and cpDNA), which have been dramatically reduced through evolutionary history. Organelle genomes form dynamic populations within present-day eukaryotic cells, akin to individuals co-evolving in a 'cellular ecosystem'. The structure of these populations is central to eukaryotic life. However, the processes shaping the content of these genomes through history, and maintaining their integrity in modern organisms, are poorly understood. This challenges our understanding of eukaryotic evolution and our ability to design rational strategies to engineer bioenergetic performance.

EvoConBiO will address these questions using a unique and unprecedented interdisciplinary approach, combining experimental characterisation and manipulation of organelle genomes with mathematical modelling and cutting-edge statistics. This highly novel combination of experiment and theory will drive the field in a new direction, for the first time uncovering the universal principles underlying the evolution and cellular control of mitochondria and chloroplasts. Our groundbreaking recent work on mtDNA suggests a common tension underlying organelle evolution, between genetic robustness (transferring genes to the nucleus) and the control and maintenance of organelles (retaining genes in organelles). EvoConBiO will reveal the pathways underlying organelle evolution, why organisms adapt to different points on these pathways, and how they resolve this underlying tension. In addition to these 'blue sky' scientific insights into a process of central evolutionary importance, we will harness our findings to 'learn from evolution' in high-risk high-reward development of new experimental strategies to engineer chloroplast performance in plants and algae of importance in EU agriculture, biofuel production, and bioengineering.'

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The information about "EVOCONBIO" are provided by the European Opendata Portal: CORDIS opendata.

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