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Uncovering and engineering the principles governing evolution and cellular control of bioenergetic organelles

Total Cost €


EC-Contrib. €






 EvoConBiO project word cloud

Explore the words cloud of the EvoConBiO project. It provides you a very rough idea of what is the project "EvoConBiO" about.

time    sky    organelle    integrity    transferring    manipulation    underlying    evolutionary    cellular    bioenergetic    mitochondria    suggests    powered    modern    uncovering    reward    form    dramatically    performance    mtdna    points    direction    insights    nucleus    bioengineering    structure    shaping    evolution    plants    chloroplasts    scientific    day    robustness    eukaryotic    genetic    engineer    independent    first    mathematical    retained    populations    cells    history    tension    chloroplast    edge    genes    maintenance    content    life    unprecedented    experiment    algae    retaining    adapt    combination    akin    originally    poorly    interdisciplinary    questions    individuals    principles    agriculture    organisms    co    maintaining    biofuel    strategies    evoconbio    blue    cutting    drive    characterisation    reveal    resolve    genomes    ecosystem    groundbreaking    rational    theory    risk    dynamic    experimental    organelles    central    combining    earth    harness    statistics    universal    cpdna   

Project "EvoConBiO" data sheet

The following table provides information about the project.


Organization address
address: MUSEPLASSEN 1
city: BERGEN
postcode: 5020

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Norway [NO]
 Total cost 1˙417˙862 €
 EC max contribution 1˙417˙862 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2018-STG
 Funding Scheme ERC-STG
 Starting year 2019
 Duration (year-month-day) from 2019-07-01   to  2024-06-30


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITETET I BERGEN NO (BERGEN) coordinator 1˙417˙862.00


 Project objective

'Complex life on Earth is powered by bioenergetic organelles -- mitochondria and chloroplasts. Originally independent organisms, these organelles have retained their own genomes (mtDNA and cpDNA), which have been dramatically reduced through evolutionary history. Organelle genomes form dynamic populations within present-day eukaryotic cells, akin to individuals co-evolving in a 'cellular ecosystem'. The structure of these populations is central to eukaryotic life. However, the processes shaping the content of these genomes through history, and maintaining their integrity in modern organisms, are poorly understood. This challenges our understanding of eukaryotic evolution and our ability to design rational strategies to engineer bioenergetic performance.

EvoConBiO will address these questions using a unique and unprecedented interdisciplinary approach, combining experimental characterisation and manipulation of organelle genomes with mathematical modelling and cutting-edge statistics. This highly novel combination of experiment and theory will drive the field in a new direction, for the first time uncovering the universal principles underlying the evolution and cellular control of mitochondria and chloroplasts. Our groundbreaking recent work on mtDNA suggests a common tension underlying organelle evolution, between genetic robustness (transferring genes to the nucleus) and the control and maintenance of organelles (retaining genes in organelles). EvoConBiO will reveal the pathways underlying organelle evolution, why organisms adapt to different points on these pathways, and how they resolve this underlying tension. In addition to these 'blue sky' scientific insights into a process of central evolutionary importance, we will harness our findings to 'learn from evolution' in high-risk high-reward development of new experimental strategies to engineer chloroplast performance in plants and algae of importance in EU agriculture, biofuel production, and bioengineering.'

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The information about "EVOCONBIO" are provided by the European Opendata Portal: CORDIS opendata.

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