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EvoConBiO SIGNED

Uncovering and engineering the principles governing evolution and cellular control of bioenergetic organelles

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 EvoConBiO project word cloud

Explore the words cloud of the EvoConBiO project. It provides you a very rough idea of what is the project "EvoConBiO" about.

evolutionary    retained    biofuel    plants    bioengineering    experiment    points    genetic    blue    maintaining    insights    originally    reward    organelles    central    maintenance    independent    performance    form    transferring    groundbreaking    content    reveal    poorly    powered    cutting    engineer    direction    individuals    dramatically    manipulation    evolution    edge    universal    scientific    suggests    combination    tension    uncovering    dynamic    organisms    sky    bioenergetic    questions    akin    mathematical    history    retaining    rational    agriculture    mitochondria    eukaryotic    resolve    drive    populations    time    cells    risk    robustness    theory    chloroplasts    harness    shaping    life    adapt    day    genes    principles    evoconbio    modern    first    structure    integrity    chloroplast    strategies    unprecedented    genomes    organelle    earth    underlying    characterisation    mtdna    nucleus    ecosystem    interdisciplinary    experimental    cellular    statistics    algae    combining    co    cpdna   

Project "EvoConBiO" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITETET I BERGEN 

Organization address
address: MUSEPLASSEN 1
city: BERGEN
postcode: 5020
website: www.uib.no

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Norway [NO]
 Total cost 1˙417˙862 €
 EC max contribution 1˙417˙862 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2018-STG
 Funding Scheme ERC-STG
 Starting year 2019
 Duration (year-month-day) from 2019-07-01   to  2024-06-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITETET I BERGEN NO (BERGEN) coordinator 1˙417˙862.00
2    THE UNIVERSITY OF BIRMINGHAM UK (BIRMINGHAM) participant 0.00

Map

Leaflet | Map data © OpenStreetMap contributors, CC-BY-SA, Imagery © Mapbox

 Project objective

'Complex life on Earth is powered by bioenergetic organelles -- mitochondria and chloroplasts. Originally independent organisms, these organelles have retained their own genomes (mtDNA and cpDNA), which have been dramatically reduced through evolutionary history. Organelle genomes form dynamic populations within present-day eukaryotic cells, akin to individuals co-evolving in a 'cellular ecosystem'. The structure of these populations is central to eukaryotic life. However, the processes shaping the content of these genomes through history, and maintaining their integrity in modern organisms, are poorly understood. This challenges our understanding of eukaryotic evolution and our ability to design rational strategies to engineer bioenergetic performance.

EvoConBiO will address these questions using a unique and unprecedented interdisciplinary approach, combining experimental characterisation and manipulation of organelle genomes with mathematical modelling and cutting-edge statistics. This highly novel combination of experiment and theory will drive the field in a new direction, for the first time uncovering the universal principles underlying the evolution and cellular control of mitochondria and chloroplasts. Our groundbreaking recent work on mtDNA suggests a common tension underlying organelle evolution, between genetic robustness (transferring genes to the nucleus) and the control and maintenance of organelles (retaining genes in organelles). EvoConBiO will reveal the pathways underlying organelle evolution, why organisms adapt to different points on these pathways, and how they resolve this underlying tension. In addition to these 'blue sky' scientific insights into a process of central evolutionary importance, we will harness our findings to 'learn from evolution' in high-risk high-reward development of new experimental strategies to engineer chloroplast performance in plants and algae of importance in EU agriculture, biofuel production, and bioengineering.'

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The information about "EVOCONBIO" are provided by the European Opendata Portal: CORDIS opendata.

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