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EvoConBiO SIGNED

Uncovering and engineering the principles governing evolution and cellular control of bioenergetic organelles

Total Cost €

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EC-Contrib. €

0

Partnership

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 EvoConBiO project word cloud

Explore the words cloud of the EvoConBiO project. It provides you a very rough idea of what is the project "EvoConBiO" about.

form    content    time    akin    experiment    independent    edge    manipulation    integrity    strategies    interdisciplinary    blue    dramatically    drive    theory    groundbreaking    genetic    plants    bioengineering    transferring    reveal    retaining    earth    cellular    engineer    mathematical    suggests    day    powered    shaping    dynamic    co    combination    rational    nucleus    populations    agriculture    maintenance    experimental    characterisation    reward    evolution    resolve    sky    underlying    organisms    cutting    modern    performance    questions    robustness    individuals    adapt    combining    scientific    chloroplasts    direction    originally    organelles    cpdna    unprecedented    genes    mtdna    poorly    retained    biofuel    ecosystem    organelle    maintaining    cells    harness    uncovering    evolutionary    points    central    principles    statistics    mitochondria    structure    universal    chloroplast    first    evoconbio    tension    risk    insights    genomes    eukaryotic    bioenergetic    life    history    algae   

Project "EvoConBiO" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITETET I BERGEN 

Organization address
address: MUSEPLASSEN 1
city: BERGEN
postcode: 5020
website: www.uib.no

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Norway [NO]
 Total cost 1˙417˙862 €
 EC max contribution 1˙417˙862 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2018-STG
 Funding Scheme ERC-STG
 Starting year 2019
 Duration (year-month-day) from 2019-07-01   to  2024-06-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITETET I BERGEN NO (BERGEN) coordinator 1˙417˙862.00
2    THE UNIVERSITY OF BIRMINGHAM UK (BIRMINGHAM) participant 0.00

Map

 Project objective

'Complex life on Earth is powered by bioenergetic organelles -- mitochondria and chloroplasts. Originally independent organisms, these organelles have retained their own genomes (mtDNA and cpDNA), which have been dramatically reduced through evolutionary history. Organelle genomes form dynamic populations within present-day eukaryotic cells, akin to individuals co-evolving in a 'cellular ecosystem'. The structure of these populations is central to eukaryotic life. However, the processes shaping the content of these genomes through history, and maintaining their integrity in modern organisms, are poorly understood. This challenges our understanding of eukaryotic evolution and our ability to design rational strategies to engineer bioenergetic performance.

EvoConBiO will address these questions using a unique and unprecedented interdisciplinary approach, combining experimental characterisation and manipulation of organelle genomes with mathematical modelling and cutting-edge statistics. This highly novel combination of experiment and theory will drive the field in a new direction, for the first time uncovering the universal principles underlying the evolution and cellular control of mitochondria and chloroplasts. Our groundbreaking recent work on mtDNA suggests a common tension underlying organelle evolution, between genetic robustness (transferring genes to the nucleus) and the control and maintenance of organelles (retaining genes in organelles). EvoConBiO will reveal the pathways underlying organelle evolution, why organisms adapt to different points on these pathways, and how they resolve this underlying tension. In addition to these 'blue sky' scientific insights into a process of central evolutionary importance, we will harness our findings to 'learn from evolution' in high-risk high-reward development of new experimental strategies to engineer chloroplast performance in plants and algae of importance in EU agriculture, biofuel production, and bioengineering.'

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The information about "EVOCONBIO" are provided by the European Opendata Portal: CORDIS opendata.

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lastchecktime (2021-05-10 5:12:08) correctly updated