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RADAR-AD SIGNED

Remote Assessment of Disease and Relapse – Alzheimer’s Disease

Total Cost €

0

EC-Contrib. €

0

Partnership

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Project "RADAR-AD" data sheet

The following table provides information about the project.

Coordinator
KING'S COLLEGE LONDON 

Organization address
address: STRAND
city: LONDON
postcode: WC2R 2LS
website: www.kcl.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Total cost 7˙640˙145 €
 EC max contribution 4˙999˙757 € (65%)
 Programme 1. H2020-EU.3.1.7. (Innovative Medicines Initiative 2 (IMI2))
 Code Call H2020-JTI-IMI2-2017-12-two-stage
 Funding Scheme IMI2-RIA
 Starting year 2019
 Duration (year-month-day) from 2019-01-01   to  2022-06-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    KING'S COLLEGE LONDON UK (LONDON) coordinator 885˙655.00
2    STICHTING VUMC NL (AMSTERDAM) participant 1˙335˙127.00
3    THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD UK (OXFORD) participant 997˙145.00
4    STICHTING LYGATURE NL (UTRECHT) participant 551˙306.00
5    THE HYVE BV NL (UTRECHT) participant 352˙352.00
6    ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS EL (THERMI THESSALONIKI) participant 266˙250.00
7    FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. DE (MUNCHEN) participant 231˙250.00
8    ALZHEIMER EUROPE LU (LUXEMBOURG) participant 230˙500.00
9    KAROLINSKA INSTITUTET SE (STOCKHOLM) participant 100˙171.00
10    AGENTSCHAP COLLEGE TER BEOORDELING VAN GENEESMIDDELEN NL (UTRECHT) participant 50˙000.00
11    ALTOIDA AG CH (LUZERN) participant 0.00
12    Eli Lilly and Company Limited UK (Basingstoke) participant 0.00
13    JANSSEN PHARMACEUTICA NV BE (BEERSE) participant 0.00
14    NOVARTIS PHARMA AG CH (BASEL) participant 0.00
15    SOFTWARE AG DE (DARMSTADT) participant 0.00
16    TAKEDA DEVELOPMENT CENTRE EUROPE LTD UK (LONDON) participant 0.00

Map

 Project objective

There is an urgent need for novel approaches assessing functional decline in early AD. The main goal of the RADAR-AD project is to develop a digital platform to detect subtle functional deficits in early Alzheimer’s disease (AD) individuals by integrating a meaningful combination of smartphone, wearable and/or home sensor based parameters. The system developed will be suitable for future longitudinal studies, including trials. The objectives are to 1) Identify the most relevant functional domains and the most promising remote measurement tools (RMTs) for these domains based on reviewing the literature and piloting of RMTs in small studies; 2) Optimise the RADAR-CNS platform for use in AD studies; 3) Test the platform and selected RMTs in a real world environment clinical study with 240 participants across the AD spectrum ranging from the preclinical AD to the dementia stage; 4) Perform statistical modelling to estimate longitudinal predictions; 5) Discuss results with regulatory agencies in order to obtain guidance about how to develop a path for formal qualification as outcome measurements in future therapeutic interventions. Considering the limited budget and project duration, we will rely upon already available technology platforms and on available longitudinal datasets where possible. The consortium includes experts in clinical dementia studies, computer science, bioinformatics, regulatory policies, ethics, and patient and public involvement (PPI). Additional strengths of the consortium are the deep and broad interface with RADAR-CNS and related IMI projects, and the access to large amount of patient-level data from key European cohort studies for modelling purposes.

 Deliverables

List of deliverables.
Focus group report on ADLs that can be monitored with RMT Documents, reports 2020-02-12 18:04:34
Generic press release to be used by all partners Websites, patent fillings, videos etc. 2020-02-12 18:04:40
Launch of website Websites, patent fillings, videos etc. 2020-02-11 09:54:05
Research protocol Documents, reports 2020-02-11 09:54:05
Report on Kick-Off meeting Documents, reports 2020-02-11 09:54:05
Preliminary Prioritized list of functional domains Documents, reports 2020-02-11 09:54:05
Develop visual identity and communication strategy Documents, reports 2020-02-11 09:54:05

Take a look to the deliverables list in detail:  detailed list of RADAR-AD deliverables.

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The information about "RADAR-AD" are provided by the European Opendata Portal: CORDIS opendata.

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