Opendata, web and dolomites

ANAT-MEC SIGNED

Developing 2-photon optical imaging for neural-network studies in medial entorhinal cortex of freely moving mice

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 ANAT-MEC project word cloud

Explore the words cloud of the ANAT-MEC project. It provides you a very rough idea of what is the project "ANAT-MEC" about.

speed    technique    thought    dimensional    first    space    miniaturized    border    computational    algorithms    behaving    mechanisms    fast    cortex    unravel    move    uses    refine    micro    exploratory    spaces    performed    unfortunately    obvious    input    entorhinal    overlapping    internal    circuit    absence    fundamental    spatial    networks    power    layer    macro    motor    tpm    behavior    largely    medial    multiple    map    mammalian    imaging    populations    position    2g    photon    time    weight    grid    besides    single    portable    appropriate    microscopy    division    unprecedented    specificity    scales    direction    types    cell    organization    cortices    head    exploring    parasubiculum    output    association    vector    neural    object    engage    navigation    resolution    light    doors    population    transformations    clear    functional    prevented    matched    adjacent    anat    naturalistic    mec    sensory    hundreds    invented    anatomical    function    functionally    mice    self    fhirm    examine    question    animals    microscope    create    directed    cells    code    recording    phd    calcium    optical    environments    shedding   

Project "ANAT-MEC" data sheet

The following table provides information about the project.

Coordinator
NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU 

Organization address
address: HOGSKOLERINGEN 1
city: TRONDHEIM
postcode: 7491
website: www.ntnu.no

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Norway [NO]
 Total cost 214˙158 €
 EC max contribution 214˙158 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2018
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2019
 Duration (year-month-day) from 2019-05-01   to  2021-04-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    NORGES TEKNISK-NATURVITENSKAPELIGE UNIVERSITET NTNU NO (TRONDHEIM) coordinator 214˙158.00

Map

 Project objective

The medial entorhinal cortex (MEC) and the adjacent pre- and parasubiculum are thought to create an internal map of self-position that animals may use for goal-directed navigation. This map uses a set of functionally specific and largely non-overlapping cell types: grid cells, border cells, speed cells, object-vector cells, and head-direction cells. The presence of multiple distinct functional cell types, matched in specificity only by cell populations in some of the sensory and motor cortices, allows us to examine input-output transformations and computational algorithms in association cortices with unprecedented power and detail. In order to examine these algorithms, however, an obvious and crucial first step is to map the division of function across cells in anatomical space. This requires recording of hundreds of cells at the same time in freely-behaving animals exploring open spatial environments. Unfortunately the absence of appropriate methods for neural recording at the population level has so far prevented a clear understanding of the broader organization of multi-cell-type and multi-layer networks of MEC, at both micro and macro scales.    During my PhD, I invented a technique called “fast high-resolution miniaturized two-photon microscopy (FHIRM-TPM)”, which, through the use of a portable light-weight (2g) two-photon microscope, allows animals to move freely while large scale, single-cell-resolution calcium imaging is performed. In ANAT-MEC, I will refine this optical imaging method to study neural activity during spatial navigation in two-dimensional environments. I shall characterize in detail the anatomical organization of distinct cell types in MEC while mice engage in naturalistic, exploratory behavior in open spaces. Besides shedding light on this specific question, the project will – by developing a new technology - also open doors to unravel fundamental mechanisms of neural code formation in the mammalian space circuit.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "ANAT-MEC" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "ANAT-MEC" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.3.2.)

Photonic Radar (2019)

Implementation of Long Reach Hybrid Photonic Radar System and convergence over FSO and PON Networks

Read More  

DIGILEAD (2020)

Digital leadership, well-being and performance in organizations

Read More  

CLIMACY (2020)

Practices of Climate Diplomacy and Uneven Policy Responses on Climate Change on Human Mobility

Read More