Opendata, web and dolomites

MIRACLE SIGNED

Metabolic Imaging with RF Antennas to predict Chemotherapy Efficacy

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 MIRACLE project word cloud

Explore the words cloud of the MIRACLE project. It provides you a very rough idea of what is the project "MIRACLE" about.

nuclear    rf    chemotherapy    society    ismrm    vegas    resonance    world    nici    phosphoethanolamine    invasively    clinical    company    establishing    breast    detecting    cell    eusobi    prediction    clinically    mri    demonstrated    track    validation    5t    metabolites    utrecht    metastasis    predict    phospholipid    spin    oncology    75    gpc    fast    invasive    linked    medicine    magnetic    uses    leads    powerful    surgery    las    801075    clearance    newly       chemistry    image    biomarkers    d6    biomarker    antennas    houses    scanned    cancer    liver    shown    metabolic    ratio    approval    pe    deliverable    conduct    minnesota    imaging    breakdown    radiology    list    7t    medical    2018    glycerophosphocholine    recognised    detection    groups    membranes    formed    fda    provides    small    2017    meeting    international    stakeholders    01    discussed    innovation    efficacy    idea    strength    fet    doctors    96    accuracy    patients    subjects    validate    umc    2016    hardware    joint    university    immediately    strongest   

Project "MIRACLE" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITAIR MEDISCH CENTRUM UTRECHT 

Organization address
address: HEIDELBERGLAAN 100
city: UTRECHT
postcode: 3584 CX
website: www.umcutrecht.nl

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Total cost 102˙500 €
 EC max contribution 100˙000 € (98%)
 Programme 1. H2020-EU.1.2.1. (FET Open)
 Code Call H2020-FETOPEN-2018-2019-2020-03
 Funding Scheme CSA
 Starting year 2019
 Duration (year-month-day) from 2019-05-01   to  2020-10-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITAIR MEDISCH CENTRUM UTRECHT NL (UTRECHT) coordinator 18˙750.00
2    WAVETRONICA BV NL (UTRECHT) participant 62˙500.00
3    REGENTS OF UNIVERSITY OF MINNESOTA US (MINNEAPOLIS MN) participant 18˙750.00

Map

 Project objective

Metabolic Imaging with RF Antennas to predict Chemotherapy Efficacy: We will validate the phospholipid biomarker that can predict response of chemotherapy in patients with breast cancer using the most powerful MRI system in the world. In particular the ratio of phosphoethanolamine (PE) to glycerophosphocholine (GPC), metabolites from the build up and breakdown of cell membranes, have been shown to increase accuracy in prediction of chemotherapy response from 75% to 96% [1]. At the clinically available field strength of 7T, we have recently demonstrated that we can image these phospholipid biomarkers non-invasively. In order to assess accuracy and bring the detection of the biomarker to FDA approval, we will spin out a validation study to investigate the accuracy in detecting the biomarker by comparing the results from the same subjects obtained at clinical MRI as well as at 10.5T MRI. The innovation idea is linked to the Non-Invasive-Chemistry-Imaging (NICI) project of FET-OPEN-01-2016-2017-801075. More specifically to the deliverable D6.1: “List of groups and stakeholders for targeted dissemination”. Here the potential of the NICI project that uses multi-nuclear 7T MRI in patients with metastasis in liver was shown to the stakeholders in breast cancer imaging (joint meeting of International Society of Magnetic Resonance in Medicine (ISMRM) with EUropean Society Of Breast Imaging (Eusobi) in Las Vegas 2018). The importance of imaging chemistry was immediately recognised by all medical doctors present (radiology, surgery and oncology), and fast track to FDA clearance was discussed. By establishing a small consortium of the UMC Utrecht that leads the project, a newly formed spin out company that provides the 7T and 10.5T specific hardware, and University of Minnesota that has access to patients and houses the world’s strongest MRI, we will conduct the biomarker validation in 10 subjects scanned at both systems.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "MIRACLE" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "MIRACLE" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.2.1.)

BRIEFING (2018)

Bridging the FET Innovation Gap

Read More  

RSENSE (2020)

Revolutionizing disease and environmental detection with portable optoacoustic sensing

Read More  

ph-coding (2019)

Predictive Haptic COding Devices In Next Generation interfaces

Read More