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GENE-SWitCH SIGNED

The regulatory GENomE of SWine and CHicken: functional annotation during development

Total Cost €

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EC-Contrib. €

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Partnership

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 GENE-SWitCH project word cloud

Explore the words cloud of the GENE-SWitCH project. It provides you a very rough idea of what is the project "GENE-SWitCH" about.

academic    benefit    evaluation    sustainable    genetic    faang    breeding    standards    fetus    space    pioneered    full    industry    genome    genomic    true    epigenome    edge    diet    add    synergy    data    strategies    cutting    populations    qtl    plan    world    gene    representing    post    switches    commercial    creation    genomes    pigs    switch    life    excellence    persist    pig    tissues    co    chicken    global    perturbations    productions    adult    functional    valuable    embryo    brings    audience    annotation    dynamics    underpinning    models    sequences    maternal    integrate    resolution    environmental    epigenetic    effort    farm    annotations    community    animal    translation    nutritional    status    shared    time    biotech    sectors    considerably    datasets    weaning    activation    stakeholders    ongoing    until    validated    paving    expression    influence    outreach    monogastric    pan    predictive    varies    variation    innovative    poultry    species    panel    conform   

Project "GENE-SWitCH" data sheet

The following table provides information about the project.

Coordinator
INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT 

Organization address
address: Rue De L'Universite 147
city: PARIS CEDEX 07
postcode: 75338
website: www.inra.fr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Total cost 5˙999˙891 €
 EC max contribution 5˙999˙886 € (100%)
 Programme 1. H2020-EU.3.2.1.1. (Increasing production efficiency and coping with climate change, while ensuring sustainability and resilience)
2. H2020-EU.3.2.3.1. (Developing sustainable and environmentally-friendly fisheries)
 Code Call H2020-SFS-2018-2
 Funding Scheme RIA
 Starting year 2019
 Duration (year-month-day) from 2019-07-01   to  2023-06-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT FR (PARIS CEDEX 07) coordinator 1˙195˙073.00
2    WAGENINGEN UNIVERSITY NL (WAGENINGEN) participant 971˙783.00
3    THE UNIVERSITY OF EDINBURGH UK (EDINBURGH) participant 905˙523.00
4    EUROPEAN MOLECULAR BIOLOGY LABORATORY DE (HEIDELBERG) participant 710˙478.00
5    DIAGENODE BE (SERAING) participant 548˙000.00
6    INSTITUT DE RECERCA I TECNOLOGIA AGROALIMENTARIES ES (CALDES DE MONTBUI BARCELONA) participant 509˙992.00
7    HENDRIX GENETICS RESEARCH,TECHNOLOGY & SERVICES BV NL (BOXMEER) participant 343˙743.00
8    UPPSALA UNIVERSITET SE (UPPSALA) participant 287˙500.00
9    INRA TRANSFERT SAS FR (PARIS) participant 209˙750.00
10    EUROPEAN FORUM OF FARM ANIMAL BREEDERS NL (WAGENINGEN) participant 197˙357.00
11    FEDERAZIONE EUROPEA DI ZOOTECNICA IT (ROMA) participant 120˙687.00

Map

 Project objective

GENE-SWitCH aims to deliver new underpinning knowledge on the functional genomes of two main monogastric farm species (pig and chicken) and to enable immediate translation to the pig and poultry sectors. The activation status of functional genome sequences varies across time and space, and in response to environmental perturbations. In full coordination and synergy with global effort and ongoing projects of the Functional Annotation of ANimal Genomes (FAANG) community, we will characterize the dynamics (“switches”) of the functional genome from embryo (chicken) and fetus (pig) to adult life by targeting a panel of tissues relevant to sustainable production. New expression QTL data in pigs and existing high-resolution QTL data in chicken will be used for developing innovative genomic predictive models that integrate functional annotations, and these models will be validated in commercial pig and poultry populations. In addition, nutritional epigenetic data will allow evaluation of the influence of maternal diet on the epigenome of the pig fetus and whether such effects persist until post-weaning. These open-shared datasets will conform fully with FAANG standards and add valuable knowledge on genetic and epigenetic variation of functional elements to FAANG. A comprehensive plan of dissemination and outreach activities to a large audience of stakeholders will be implemented. The GENE-SWitCH consortium brings together partners representing pan-European excellence (including the academic institutions which pioneered FAANG) and world-leading animal breeding and biotech industry in a true co-creation effort. Overall, GENE-SWitCH will contribute to the global FAANG effort considerably, demonstrate how functional annotation of genomes can foster the advancement of genomic selection for immediate benefit to the breeding industry, and produce cutting-edge research paving the way to new studies and strategies for sustainable productions.

 Deliverables

List of deliverables.
GENE-SWitCH Data Management Plan Open Research Data Pilot 2020-04-25 13:33:44
Outreach, dissemination, and training plan Documents, reports 2020-04-25 13:33:44

Take a look to the deliverables list in detail:  detailed list of GENE-SWitCH deliverables.

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