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iLCA SIGNED

Intelligent Live Cell Analysis [iLCA] to transform disease management through faster, and more regulatory robust, discovery, manufacture and monitoring of biologic drugs & cell therapies

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

iLCA project word cloud

Explore the words cloud of the iLCA project. It provides you a very rough idea of what is the project "iLCA" about.

master validation image cycle factories banks workflows ex potentially markets behalf vivo medicines shed cld regulatory external market expensive complete last suited global intense size discovery therapy single documentation entry diverse time drugs therapies preparation continued relatively drug of cell quality editing faster forefront themselves ideally diagnostics disease made manufacturing antibody aggressively crude select decades workflow engineering fti consuming commercial competitor transformative multiple speed dramatic recording biologic ultimately ing provides platform manufactured entire marketed attributes globally fundraising life cheaper critical gene innovation line penetration competition diagnostic cells imaging live companies human automation attracting requirement patients sme

Project "iLCA" data sheet

The following table provides information about the project.

Coordinator	VALITACELL LTD Organization address address: FOSTERS AVE. - MOUNT MERRION, BLACKROCK city: DUBLIN 2 postcode: V94 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Ireland [IE]
Project website	https://www.valitacell.com/fti-ilca
Total cost	3˙483˙633 €
EC max contribution	2˙438˙543 € (70%)
Programme	1. H2020-EU.3. (PRIORITY 'Societal challenges) 2. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
Code Call	H2020-EIC-FTI-2018-2020
Funding Scheme	IA
Starting year	2019
Duration (year-month-day)	from 2019-06-01 to 2021-05-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	VALITACELL LTD VALITACELL LTD Organization address address: FOSTERS AVE. - MOUNT MERRION, BLACKROCK city: DUBLIN 2 postcode: V94 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IE (DUBLIN 2)	coordinator	1˙135˙667.00
2	SOLENTIM LTD SOLENTIM LTD Organization address address: SOLENT HOUSE 3 JOHNSON ROAD FERNSID city: WIMBORNE postcode: BH21 7SE website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (WIMBORNE)	participant	708˙421.00
3	MICROCOAT BIOTECHNOLOGIE GMBH MICROCOAT BIOTECHNOLOGIE GMBH Organization address address: AM NEULAND 3 city: BERNRIED postcode: 82347 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (BERNRIED)	participant	594˙454.00

Map

Project objective

The detailed analysis of live cells, as shed elements of a human disease process, cell therapies themselves or as factories for the production of biologic drugs, is attracting intense focus globally from diverse companies in automation, imaging, diagnostics and manufacturing. This proposal is made on behalf of a consortium of 3 European SME’s to support the validation and preparation for commercial take-up of the market entry application, Cell Line Development [CLD], of a new transformative technology at the forefront of these areas and is ideally suited for cell line development, antibody discovery, gene editing, cell therapy, antibody engineering and ex-vivo diagnostic workflows. Each workflow provides a dramatic increase in insight, control, speed and cost, ultimately resulting in faster, cheaper and more regulatory robust medicines for European patients. Biologic drugs are large in size and are manufactured from a single cell selected following an expensive, relatively crude and time consuming process - Cell Line Development. Our technology can select the 'Top' cell using a detailed analysis of the critical quality attributes along with providing complete image recording and documentation of the growth from a single cell [regulatory requirement]. This cell selection and control is essential as all resulting master and working cell banks are used over the entire lifeâ€cycle of the marketed product that can last multiple decades. This FTI funding will enable market entry and validation & support external fundraising for the wider penetration of the global drug discovery, Cell therapy & ex-vivo diagnostic markets. This is a potentially transformative technology platform in a very large market with 1 current aggressively funded US competitor and our success will ensure competition, continued innovation and most importantly cheaper medicines for European patients.

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