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PROTON SIGNED

Proton transport and proton-coupled transport

Total Cost €

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EC-Contrib. €

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Partnership

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 PROTON project word cloud

Explore the words cloud of the PROTON project. It provides you a very rough idea of what is the project "PROTON" about.

cancer    cells    biofuel    membrane    substances    strategies    technologies    transporter    cross    biomimetic    layers    pharmacologically    water    single    relay    settings    bioengineering    positions    proton    transfer    practical    basic    synthetic    protein    moieties    drug    molecule    multidisciplinary    serve    comprising    cavities    gastritis    calculations    sustainable    reaction    ulcers    interfacial    incomplete    phd    improvement    channel    skills    preparing    health    fuel    cutting    human    channels    science    diseases    qualify    curing    migration    reactions    spectroscopy    threats    interdisciplinary    competitive    details    transferable    disciplinary    interfere    obesity    private    imaging    edge    acquire    employability    duodenal    containing    arrangement    industry    harmonic    energy    rational    clarifying    solutions    responsible    transporters    confines    gastric    students    kinds    highest    public    scientific    secure    train    industrial    microscopy    time    fluorescence    chronic    holds    resolved    sectors    mechanism    proteinaceous    emphasis    humanity    training    structures    transport    mobility    solid    resolve    generate    societies    hampered    15    unresolved    molecular    close    solving   

Project "PROTON" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITAT LINZ 

Organization address
address: ALTENBERGER STRASSE 69
city: LINZ
postcode: 4040
website: www.jku.at

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Austria [AT]
 Total cost 3˙976˙976 €
 EC max contribution 3˙976˙976 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2019
 Funding Scheme MSCA-ITN-ETN
 Starting year 2019
 Duration (year-month-day) from 2019-09-01   to  2023-08-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITAT LINZ AT (LINZ) coordinator 528˙414.00
2    UNIVERSITETET I OSLO NO (OSLO) participant 584˙684.00
3    ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE CH (LAUSANNE) participant 562˙553.00
4    CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS FR (PARIS) participant 274˙802.00
5    VETERINAERMEDIZINISCHE UNIVERSITAET WIEN AT (VIENNA) participant 264˙207.00
6    THE HEBREW UNIVERSITY OF JERUSALEM IL (JERUSALEM) participant 263˙500.00
7    BOEHRINGER INGELHEIM PHARMA GMBH &CO KG DE (INGELHEIM) participant 252˙788.00
8    CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL DE (KIEL) participant 252˙788.00
9    FREIE UNIVERSITAET BERLIN DE (BERLIN) participant 252˙788.00
10    INTANA BIOSCIENCE GMBH DE (PLANEGG MARTINSRIED) participant 252˙788.00
11    UNIVERSITAT DES SAARLANDES DE (SAARBRUCKEN) participant 252˙788.00
12    USTAV FYZIKALNI CHEMIE J. HEYROVSKEHO AV CR, v. v. i. CZ (PRAHA) participant 234˙871.00

Map

Leaflet | Map data © OpenStreetMap contributors, CC-BY-SA, Imagery © Mapbox

 Project objective

Secure, competitive, and sustainable energy production is a major challenge facing human societies. Biomimetic solutions such as the development of new biofuel cells are hampered by our thus far incomplete understanding of proton transfer reactions. The same holds for health threats to humanity: Curing diseases like cancer, obesity, chronic gastritis, gastric and duodenal ulcers, requires to pharmacologically interfere - in their molecular details - with yet unresolved proton transfer reactions. Here we aim at clarifying the molecular reaction mechanism in the confines of interfacial water layers and proteinaceous cavities with emphasis on arrangement and mobility of proton relay moieties. Achieving this requires an interdisciplinary, multi-level approach comprising cutting edge technologies like second harmonic imaging, single molecule and time resolved fluorescence microscopy and spectroscopy, advanced calculations of proton transfer, bioengineering of membrane channel and transporter containing systems, synthetic design of biomimetic proton channels, solving protein structures and rational drug design.

PROTON will train 15 PhD students, who will acquire a solid state-of-the-art multidisciplinary scientific training in all kinds of proton migration/reaction systems, covering from basic science to industrial applications, thus preparing them to generate new scientific knowledge of the highest impact. In addition, practical training on transferable skills will increase their employability and qualify them for responsible positions in private and public sectors. Cross-disciplinary strategies and close collaboration with industry will enable them to resolve the molecular details of proton driven processes in all kinds of settings - enabling the improvement of biomimetic applications – up to fuel cells - and to identify lead substances which may serve to pharmacologically interfere with proton transport through membrane channels and transporters.

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The information about "PROTON" are provided by the European Opendata Portal: CORDIS opendata.

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