Opendata, web and dolomites

miniNO SIGNED

Associative mechanisms linking a defective minipuberty to the appearance of mental and nonmental disorders: infantile NO replenishment as a new therapeutic possibility

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 miniNO project word cloud

Explore the words cloud of the miniNO project. It provides you a very rough idea of what is the project "miniNO" about.

birth    lifelong    signaling    interdisciplinary    autism    concerning    minino    reduce    screening    clinicians    neuroscientists    deficiency    personalized    social    prematurely    alt    altered    biomarkers    cohorts    diagnostic    preterm    hypothalamic    infancy    data    lifestyle    combining    multimorbidity    tools    maturation    alterations    prematurity    memory    infertility    clinical    financial    assembled    cardiovascular    options    gender    appear    validating    abnormalities    pediatric    anosmia    oxide    newly    nitric    millions    activation    infantile    cognition    causative    sme    brain    mental    disorders    treatment    geneticists    premature    societal    molecular    burdens    tests    endocrinologists    impairments    born    first    life    therapeutic    transient    preventive    gonadal    later    basic    minipuberty    renowned    association    mechanisms    learning    quality    created    preclinical    pituitary    genetic    metabolic    axis    adult    impairements    scientists    impose    paving    psychiatrists    hearing    comorbidities    environmental    time    individuals   

Project "miniNO" data sheet

The following table provides information about the project.

Coordinator
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE 

Organization address
address: RUE DE TOLBIAC 101
city: PARIS
postcode: 75654
website: www.inserm.fr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Total cost 6˙487˙770 €
 EC max contribution 6˙487˙770 € (100%)
 Programme 1. H2020-EU.3.1.1. (Understanding health, wellbeing and disease)
 Code Call H2020-SC1-2019-Two-Stage-RTD
 Funding Scheme RIA
 Starting year 2020
 Duration (year-month-day) from 2020-01-01   to  2025-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE FR (PARIS) coordinator 943˙750.00
2    CENTRE HOSPITALIER UNIVERSITAIRE VAUDOIS CH (LAUSANNE) participant 1˙338˙243.00
3    CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE FR (LILLE) participant 742˙188.00
4    EREVNITIKO PANEPISTIMIAKO INSTITUTOMELETIS KE ANTIMETOPISIS GENETIKONKE KAKOETHON NOSIMATON TIS PEDIKISILIKIAS EL (ATHINA) participant 617˙500.00
5    QUEEN MARY UNIVERSITY OF LONDON UK (LONDON) participant 578˙332.00
6    UNIVERSITE DE LILLE FR (LILLE) participant 539˙605.00
7    BIOGAZELLE NV BE (ZWIJNAARDE) participant 499˙000.00
8    UNIVERSITAET zu LUEBECK DE (LUBECK) participant 481˙025.00
9    INSERM TRANSFERT SA FR (PARIS) participant 400˙375.00
10    UNIVERSITE DE GENEVE CH (GENEVE) participant 347˙750.00

Map

 Project objective

The miniNO project aims to identify the key causative mechanisms of the lifelong multimorbidity associated with preterm birth. Prematurity is associated with altThe miniNO project aims to identify the key causative mechanisms of the lifelong multimorbidity associated with preterm birth. Prematurity is associated with alterations in the maturation of the hypothalamic-pituitary-gonadal axis, and specifically with its transient activation during infancy, known as minipuberty. miniNO will study for the first time the association between premature birth and alterations in minipuberty and infantile nitric oxide (NO) signaling in the brain, and comorbidities that appear later on in life. The project is based on robust preclinical data and previous clinical studies, and will exploit data concerning premature birth and minipuberty in existing cohorts as well as newly created cohorts. We will identify the molecular association between NO deficiency, altered minipuberty and multimorbidity combining mental (e.g. autism, social cognition, learning and memory impairments) and non-mental disorders (e.g. anosmia, hearing loss, metabolic abnormalities, cardiovascular impairements and infertility) as well as gender, environmental and lifestyle factors. For this, we have assembled a unique interdisciplinary consortium of renowned basic scientists (neuroscientists) and clinicians (pediatric and adult endocrinologists, psychiatrists, geneticists) and an SME to implement the project results. By validating the causative mechanisms of the multimorbidity related to preterm birth, we will propose and develop novel diagnostic and preventive tools, including screening tests for biomarkers and newly identified genetic factors, for altered minipuberty, thus paving the way to personalized treatment and new therapeutic options very early in life. miniNO is expected to improve the quality of life of millions of prematurely born individuals and reduce the financial and societal burdens they impose.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "MININO" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "MININO" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.3.1.1.)

BIND (2020)

Brain Involvement iN Dystrophinopathies

Read More  

SoNAR-Global (2019)

A Global Social Sciences Network for Infectious Threats and Antimicrobial Resistance

Read More  

OBERON (2019)

An integrative strategy of testing systems for identification of EDs related to metabolic disorders

Read More