PROFID SIGNED
Implementation of personalised risk prediction and prevention of sudden cardiac death after myocardial infarction
Total Cost €
0EC-Contrib. €
0Partnership
0Views
0PROFID project word cloud
Explore the words cloud of the PROFID project. It provides you a very rough idea of what is the project "PROFID" about.
Project "PROFID" data sheet
The following table provides information about the project.
| Coordinator |
LEIPZIG HEART INSTITUTE GMBH
Organization address contact info |
| Coordinator Country | Germany [DE] |
| Total cost | 23˙381˙704 € |
| EC max contribution | 19˙884˙569 € (85%) |
| Programme |
1. H2020-EU.3.1.6. (Health care provision and integrated care) |
| Code Call | H2020-SC1-2019-Two-Stage-RTD |
| Funding Scheme | IA |
| Starting year | 2020 |
| Duration (year-month-day) | from 2020-01-01 to 2024-12-31 |
Partnership
Take a look of project's partnership.
Map
Project objective
Sudden cardiac death (SCD) is a major public health problem accounting for ~20% of all deaths in Europe with an estimated yearly incidence of ~350-700,000, often in patients with previous myocardial infarction (MI). In SCD, the heart suddenly and unexpectedly stops beating. If untreated, the patient dies within minutes, but SCD can be successfully prevented by an implantable cardioverter-defibrillator (ICD). The ICD is highly effective, but is associated with potentially severe complications and high healthcare costs. Based on historical evidence, guidelines recommend prophylactic ICD implantation in post-MI patients with left ventricular ejection fraction (LVEF)≤35% to prevent SCD. However, only a minority of these patients will ever need the device. In addition, in absolute numbers the majority of SCD cases occurs in patients with LVEF>35% who are currently not considered for prophylactic ICD. Due to the inherent risks and considerable health care expenditures, a personalised treatment approach for ICD implantation is urgently required. Using state-of-the-art methods and large clinical datasets from established international cohorts and registries across different European geographies, PROFID will develop a clinical decision support tool (risk score) to predict the individual SCD risk and identify those post-MI patients that will optimally benefit from an ICD. Two parallel randomised clinical trials will validate implementation of the risk score to determine ICD implantation, while health economic analyses will assess its economic impact on health care systems. A software tool for clinical use of the risk score will be implemented, and a pilot run in 3 European regions with participation of insurance companies and authorities. The unique composition of the consortium with key opinion leaders, patient organisations, large hospital chains, payers, policy makers and state authorities across Europe, will ensure implementation into routine clinical practice.
Are you the coordinator (or a participant) of this project? Plaese send me more information about the "PROFID" project.
For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.
Send me an email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.
Thanks. And then put a link of this page into your project's website.
The information about "PROFID" are provided by the European Opendata Portal: CORDIS opendata.
More projects from the same programme (H2020-EU.3.1.6.)
HTx (2019)
Next Generation Health Technology Assessment to support patient-centred, societally oriented, real-time decision-making on access and reimbursement for health technologies throughout Europe
Read More