BRASINOEU

Translocation and Safe Design of Surface Engineered Metal oxide Nanoparticles

 Coordinatore UNIVERSITAET LEIPZIG 

 Organization address address: RITTERSTRASSE 26
city: LEIPZIG
postcode: 4109

contact info
Titolo: Dr.
Nome: Irina
Cognome: Estrela-Lopis
Email: send email
Telefono: +49 3419715702
Fax: +49 3419715709

 Nazionalità Coordinatore Germany [DE]
 Totale costo 428˙400 €
 EC contributo 428˙400 €
 Programma FP7-PEOPLE
Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
 Code Call FP7-PEOPLE-2012-IRSES
 Funding Scheme MC-IRSES
 Anno di inizio 2013
 Periodo (anno-mese-giorno) 2013-01-01   -   2016-12-31

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    UNIVERSITAET LEIPZIG

 Organization address address: RITTERSTRASSE 26
city: LEIPZIG
postcode: 4109

contact info
Titolo: Dr.
Nome: Irina
Cognome: Estrela-Lopis
Email: send email
Telefono: +49 3419715702
Fax: +49 3419715709

DE (LEIPZIG) coordinator 98˙700.00
2    ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOMATERIALES

 Organization address address: PASEO MIRAMON PARQUE TECNOLOGICO DE SAN SEBASTIAN EDIFICIO EMPRESARIAL C 182
city: SAN SEBASTIAN
postcode: 20009

contact info
Titolo: Mr.
Nome: Alfonso
Cognome: Egaña
Email: send email
Telefono: +34 943005300
Fax: +34 943 005 301

ES (SAN SEBASTIAN) participant 199˙500.00
3    TYOETERVEYSLAITOS

 Organization address address: Topeliuksenkatu 41 a A
city: HELSINKI
postcode: 250

contact info
Titolo: Dr.
Nome: Julia
Cognome: Catalán
Email: send email
Telefono: +358 30 474 2210

FI (HELSINKI) participant 65˙100.00
4    INSTYTUT FIZYKI POLSKIEJ AKADEMII NAUK

 Organization address address: AL LOTNIKOW 32/46
city: WARSZAWA
postcode: 02 668

contact info
Titolo: Dr.
Nome: Ewa
Cognome: Mosiniewicz-Szablewska
Email: send email
Telefono: +4822 8435212
Fax: +4822 8430926

PL (WARSZAWA) participant 33˙600.00
5    WARSZAWSKI UNIWERSYTET MEDYCZNY

 Organization address address: UL. ZWIRKI I WIGURY 61
city: WARSZAWA
postcode: 2091

contact info
Titolo: Mrs.
Nome: Joanna
Cognome: Sobczak
Email: send email
Telefono: +4822 5720469
Fax: +4822 5720405

PL (WARSZAWA) participant 31˙500.00

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

synthesis    quantification    genotoxicity    magnetic    nanotechnology    fundamental    microscopy    translocation    imaging    international    safe    modification    nanosafety    metal    surface    cellular    groups    oxide    complementary    scientific    nps   

 Obiettivo del progetto (Objective)

'BRASINOEU aims to study the translocation and nanosafety issues of engineered metal oxide nanoparticles (NPs).The new scientific and technology developments of nanotechnology require a deeper knowledge of the effects of nanotechnology based products on human health. This knowledge is fundamental for the development of nanotechnology and to achieve its full acceptance. The concept of “safe by design” is based on the application of nanosafety to design the nanomaterials in order to prevent or reduce their possible harm to humans and the environment. The project encompass the synthesis of metal oxide NPs, with a focus on magnetic oxides, their surface modification and post modification in biological fluids; immunological and genotoxicity studies, and translocation studies both “in vitro” and “in vivo”. The project will seek to establish relationships between designed NP properties and their translocation at cellular and body level as well as their immune- and genotoxic response. This is a fundamental issue for the safe design of NPs. Also, the toxicological response will be studied as a function of the uptake dose of NPs. At cellular level a battery of techniques will be applied for localization and quantification of NPs: Transmission Electron Microscopy, Raman, Confocal Microscopy, Ion Beam Microscopy, etc. Positron Emission Tomography and Magnetic Resonance Imaging will be employed for biodistribution and quantification studies in animal models. BRASINOU is formed by an international team with the required and complementary expertise to address the proposed work from an international and multidisciplinary perspective. The project gathers internationally recognized groups in immunology, genotoxicity, nanoparticle synthesis, surface chemistry, biophysics, imaging and materials science. The complementary of the groups involved in the project will help to develop new highly skilled professional and scientific horizontal connections.'

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