NANOSOLUTIONS

Biological Foundation for the Safety Classification of Engineered Nanomaterials (ENM): Systems Biology Approaches to Understand Interactions of ENM with Living Organisms and the Environment

 Coordinatore TYOETERVEYSLAITOS 

 Organization address address: Topeliuksenkatu 41 a A
city: HELSINKI
postcode: 250

contact info
Titolo: Prof.
Nome: Kai
Cognome: Savolainen
Email: send email
Telefono: +358 30 474 2200
Fax: +358 30 474 2114

 Nazionalità Coordinatore Finland [FI]
 Sito del progetto http://nanosolutionsfp7.com
 Totale costo 13˙765˙733 €
 EC contributo 10˙000˙000 €
 Programma FP7-NMP
Specific Programme "Cooperation": Nanosciences, Nanotechnologies, Materials and new Production Technologies
 Code Call FP7-NMP-2012-LARGE-6
 Funding Scheme CP-IP
 Anno di inizio 2013
 Periodo (anno-mese-giorno) 2013-04-01   -   2017-03-31

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    TYOETERVEYSLAITOS

 Organization address address: Topeliuksenkatu 41 a A
city: HELSINKI
postcode: 250

contact info
Titolo: Prof.
Nome: Kai
Cognome: Savolainen
Email: send email
Telefono: +358 30 474 2200
Fax: +358 30 474 2114

FI (HELSINKI) coordinator 1˙913˙591.59
2    KAROLINSKA INSTITUTET

 Organization address address: Nobels Vag 5
city: STOCKHOLM
postcode: 17177

contact info
Titolo: Mr.
Nome: Per-Olof
Cognome: Larsson
Email: send email
Telefono: +46 8 524 875 00
Fax: +46 8 33 69 81

SE (STOCKHOLM) participant 1˙394˙999.60
3    UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN

 Organization address address: BELFIELD
city: DUBLIN
postcode: 4

contact info
Titolo: Mr.
Nome: Donal
Cognome: Doolan
Email: send email
Telefono: 35317161656
Fax: 35317161216

IE (DUBLIN) participant 580˙051.00
4    LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN

 Organization address address: GESCHWISTER SCHOLL PLATZ 1
city: MUENCHEN
postcode: 80539

contact info
Titolo: Prof.
Nome: Fritz
Cognome: Krombach
Email: send email
Telefono: +49 89 218076540
Fax: +49 89 218076532

DE (MUENCHEN) participant 464˙100.00
5    UNIVERSITY OF PLYMOUTH

 Organization address address: DRAKE CIRCUS
city: PLYMOUTH
postcode: PL4 8AA

contact info
Titolo: Prof.
Nome: Richard
Cognome: Handy
Email: send email
Telefono: +44 1752584630

UK (PLYMOUTH) participant 414˙064.80
6    INSIGHT PUBLISHERS LIMITED

 Organization address address: KING SQUARE 12-13
city: BRISTOL
postcode: BS2 8JH

contact info
Titolo: Mr.
Nome: William
Cognome: Davis
Email: send email
Telefono: 441172000000
Fax: 441173000000

UK (BRISTOL) participant 399˙240.00
7    ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOMATERIALES

 Organization address address: PASEO MIRAMON PARQUE TECNOLOGICO DE SAN SEBASTIAN EDIFICIO EMPRESARIAL C 182
city: SAN SEBASTIAN
postcode: 20009

contact info
Titolo: Mr.
Nome: Alfonso
Cognome: Egaña
Email: send email
Telefono: +34 943005300
Fax: +34 943 005 301

ES (SAN SEBASTIAN) participant 365˙000.00
8    MISVIK BIOLOGY OY

 Organization address address: ITAINEN PITKAKATU 4 B
city: TURKU
postcode: 20520

contact info
Titolo: Dr.
Nome: Vesa
Cognome: Hongisto
Email: send email
Telefono: 358401000000

FI (TURKU) participant 350˙562.98
9    INSTITUTE OF OCCUPATIONAL MEDICINE

 Organization address address: Research Avenue North, Riccarton 45
city: EDINBURGH
postcode: EH14 4AP

contact info
Titolo: Ms.
Nome: Susy
Cognome: Makari
Email: send email
Telefono: +44 131 449 8065
Fax: +44 131 449 8084

UK (EDINBURGH) participant 339˙686.29
10    HERIOT-WATT UNIVERSITY

 Organization address address: Riccarton
city: EDINBURGH
postcode: EH14 4AS

contact info
Titolo: Dr.
Nome: Eva
Cognome: Olszewska-Day
Email: send email
Telefono: +44 131 4513073
Fax: +44 131 4513193

UK (EDINBURGH) participant 299˙999.60
11    EIDGENOESSISCHE MATERIALPRUEFUNGS- UND FORSCHUNGSANSTALT

 Organization address address: Ueberlandstrasse 129
city: DUEBENDORF
postcode: 8600

contact info
Titolo: Dr.
Nome: Peter
Cognome: Wick
Email: send email
Telefono: +41 58 765 76 84

CH (DUEBENDORF) participant 290˙000.00
12    DANMARKS TEKNISKE UNIVERSITET

 Organization address address: Anker Engelundsvej 1, Building 101A
city: KONGENS LYNGBY
postcode: 2800

contact info
Titolo: Dr.
Nome: Jørgen
Cognome: Schlundt
Email: send email
Telefono: 4535887703
Fax: 4535887448

DK (KONGENS LYNGBY) participant 289˙999.75
13    ACONDICIONAMIENTO TARRASENSE ASSOCIACION

 Organization address address: CARRER DE LA INNOVACIO 2
city: TERRASSA
postcode: 8225

contact info
Titolo: Dr.
Nome: Amro
Cognome: Satti
Email: send email
Telefono: +34 93 788 23 00
Fax: +34 93 789 19 06

ES (TERRASSA) participant 274˙152.00
14    UNIVERSITAET LEIPZIG

 Organization address address: RITTERSTRASSE 26
city: LEIPZIG
postcode: 4109

contact info
Titolo: Dr.
Nome: Irina
Cognome: Estrela-Lopis
Email: send email
Telefono: +49 341 9715702
Fax: +49 341 9715709

DE (LEIPZIG) participant 250˙000.40
15    UNIVERSITE DE BORDEAUX

 Organization address address: PLACE PEY BERLAND 35
city: BORDEAUX
postcode: 33000

contact info
Titolo: Mrs.
Nome: Katel
Cognome: Goeden
Email: send email
Telefono: +33 5 40002209

FR (BORDEAUX) participant 250˙000.40
16    TURUN YLIOPISTO

 Organization address address: YLIOPISTONMAKI
city: TURUN YLIOPISTO
postcode: 20014

contact info
Titolo: Dr.
Nome: Mari
Cognome: Riipinen
Email: send email
Telefono: +358 2 3336054
Fax: +358 2 3336446

FI (TURUN YLIOPISTO) participant 249˙999.00
17    FONDAZIONE TELETHON

 Organization address address: VIA VARESE 16/B
city: ROMA
postcode: 185

contact info
Titolo: Dr.
Nome: Irene
Cognome: Mearelli
Email: send email
Telefono: +39 06 44015308

IT (ROMA) participant 249˙996.80
18    NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO

 Organization address address: Schoemakerstraat 97
city: DEN HAAG
postcode: 2600 JA

contact info
Titolo: Dr.
Nome: Esther
Cognome: Zondervan-Van Den Beuken
Email: send email
Telefono: +31 88866 1581

NL (DEN HAAG) participant 244˙894.75
19    THE UNIVERSITY OF MANCHESTER

 Organization address address: OXFORD ROAD
city: MANCHESTER
postcode: M13 9PL

contact info
Titolo: Ms.
Nome: Claire
Cognome: Faichnie
Email: send email
Telefono: +44 1612751413

UK (MANCHESTER) participant 244˙566.12
20    BIOBYTE SOLUTIONS GMBH

 Organization address address: Bothestrasse 142
city: Heidelberg
postcode: 69126

contact info
Titolo: Dr.
Nome: Ivica
Cognome: Letunic
Email: send email
Telefono: 491728000000

DE (Heidelberg) participant 150˙000.00
21    BIOTESYS GMBH

 Organization address address: SCHELZTORSTRASSE 54-56
city: ESSLINGEN
postcode: 73728

contact info
Titolo: Dr.
Nome: Dirk
Cognome: Dressler
Email: send email
Telefono: 4971130000000
Fax: +49 711 31057151

DE (ESSLINGEN) participant 150˙000.00
22    PLASMACHEM PRODUKTIONS- UND HANDEL GMBH

 Organization address address: RUDOWER CHAUSSEE 29
city: BERLIN
postcode: 12489

contact info
Titolo: Dr.
Nome: Alexey
Cognome: Kalachev
Email: send email
Telefono: +49 30 63926316

DE (BERLIN) participant 149˙996.00
23    INKOA SISTEMAS SL

 Organization address address: "CALLE RIBERA DE AXPE 11, EDIFICIO D1"
city: ERANDIO
postcode: 48950

contact info
Titolo: Mrs.
Nome: Idoia
Cognome: Unzueta
Email: send email
Telefono: +34 94 418 02 67

ES (ERANDIO) participant 126˙240.00
24    Nome Ente NON disponibile

 Organization address address: Campus Universitario Darcy Ribeiro
city: Brasilia
postcode: 70910-900

contact info
Titolo: Prof.
Nome: Paulo Cesar
Cognome: De Morais
Email: send email
Telefono: +55 61 32736655
Fax: +55 61 32723151

BR (Brasilia) participant 100˙000.00
25    Zhejiang University

 Organization address address: ZHE DA ROAD 38
city: HANGZHOU
postcode: 310027

contact info
Titolo: Prof.
Nome: Changyou
Cognome: Gao
Email: send email
Telefono: +86 571 87951108
Fax: +86 571 87951108

CN (HANGZHOU) participant 100˙000.00
26    NATIONAL HEALTH LABORATORY SERVICES

 Organization address address: MODDERFONTEIN ROAD 1 GAUTENG
city: SANDRINGHAM
postcode: 2131

contact info
Titolo: Prof.
Nome: Mary
Cognome: Gulumian
Email: send email
Telefono: 27117126428

ZA (SANDRINGHAM) participant 80˙000.00
27    NOORDWES-UNIVERSITEIT

 Organization address address: HOFFMAN STREET 11
city: POTCHEFSTROOM
postcode: 2531

contact info
Titolo: Prof.
Nome: Victor
Cognome: Wepener
Email: send email
Telefono: 27182992385
Fax: 27182992370

ZA (POTCHEFSTROOM) participant 80˙000.00
28    TEKNOLOGIAN TUTKIMUSKESKUS VTT

 Organization address address: TEKNIIKANTIE 4 A
city: ESPOO
postcode: 02044 VTT

contact info
Titolo: Prof.
Nome: Roland
Cognome: Grafström
Email: send email
Telefono: +358 40 739 8443
Fax: +358 20 722 2840

FI (ESPOO) participant 50˙986.14
29    UNIVERSITA DEGLI STUDI DI SALERNO

 Organization address address: VIA GIOVANNI PAOLO II 132
city: FISCIANO (SA)
postcode: 84084

contact info
Titolo: Prof.
Nome: Tagliaferri
Cognome: Roberto
Email: send email
Telefono: +39 89 0968231
Fax: +39 89 0969600

IT (FISCIANO (SA)) participant 50˙000.00
30    NANOLOGICA AB

 Organization address city: Stockholm
postcode: 114 28

contact info
Titolo: Dr.
Nome: Roberto Hanoi
Cognome: Labrador Montero
Email: send email
Telefono: 46737259452

SE (Stockholm) participant 20˙000.40
31    POLIMEROS Y SISTEMAS DE APLICACION TECNICA SL

 Organization address address: "CALLE CAPCIR 12, POL IND PLACA DE LA BRUGUERA"
city: CASTELLAR DEL VALLES
postcode: 8211

contact info
Titolo: Mr.
Nome: Amado
Cognome: Lacruz
Email: send email
Telefono: +34 937146960
Fax: +34 937142802

ES (CASTELLAR DEL VALLES) participant 19˙880.00
32    POLYMER FACTORY SWEDEN AB

 Organization address address: KRISTINEDALSVAGEN 48
city: NACKA
postcode: 13146

contact info
Titolo: Dr.
Nome: Andreas
Cognome: Nyström
Email: send email
Telefono: +46 73 6554679

SE (NACKA) participant 19˙785.00
33    NANOCYL SA

 Organization address address: RUE DE L'ESSOR 4
city: SAMBREVILLE
postcode: 5060

contact info
Titolo: Mrs.
Nome: Nathalie
Cognome: Luizi
Email: send email
Telefono: 3271750671
Fax: 3271750670

BE (SAMBREVILLE) participant 19˙040.00
34    SOLVAY SA

 Organization address address: RUE DE RANSBEEK 310
city: BRUXELLES
postcode: 1120

contact info
Titolo: Dr.
Nome: Erik
Cognome: Van Miert
Email: send email
Telefono: 3222642691
Fax: 322652990

BE (BRUXELLES) participant 13˙733.50
35    UNIVERSITY COLLEGE LONDON

 Organization address address: GOWER STREET
city: LONDON
postcode: WC1E 6BT

contact info
Titolo: Mrs.
Nome: Borg-Carbott
Cognome: Greta
Email: send email
Telefono: +44 2031083033
Fax: 442078000000

UK (LONDON) participant 5˙433.88
36    LEIDOS BIOMEDICAL RESEARCH INC

 Organization address address: BOYLES STREET 1050
city: FREDERICK MD
postcode: 21702

contact info
Titolo: Dr.
Nome: Scott
Cognome: Mcneil
Email: send email
Telefono: +301 846 6939

US (FREDERICK MD) participant 0.00
37    NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH

 Organization address address: WILLOWDALE ROAD MS L 2015
city: MORGANTOWN
postcode: 26505

contact info
Titolo: Prof.
Nome: Anna
Cognome: Shvedova
Email: send email
Telefono: +1 304 285 6177
Fax: +1 304 285 5938

US (MORGANTOWN) participant 0.00
38    UNIVERSITE BORDEAUX I

 Organization address address: 351 Cours de la Liberation
city: TALENCE
postcode: 33405

contact info
Titolo: Mrs.
Nome: Katel
Cognome: Goeden
Email: send email
Telefono: +33 5 40002209

FR (TALENCE) participant 0.00

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

biological    safety    organism    physico    cellular    core    toxicity    levels    determine    bio    surface    organisms    enm    corona    governed    functions    material    molecule    chemical   

 Obiettivo del progetto (Objective)

'The main objective of this research proposal is to identify and elaborate those characteristics of ENM that determine their biological hazard potential. This potential includes the ability of ENM to induce damage at the cellular, tissue, or organism levels by interacting with cellular structures leading to impairment of key cellular functions. These adverse effects may be mediated by ENM-induced alterations in gene expression and translation, but may involve also epigenetic transformation of genetic functions. We believe that it will be possible to create a set of biomarkers of ENM toxicity that are relevant in assessing and predicting the safety and toxicity of ENM across species. The ENM-organism interaction is complex and depends, not simply on the composition of ENM core, but particularly on its physico-chemical properties. In fact, important physico-chemical properties are largely governed by their surface properties. All of these factors determine the binding of different biomolecules on the surface of the ENM, the formation of a corona around the ENM core. Thus, any positive or negative biological effect of ENM in organisms may be dynamically modulated by the bio-molecule corona associated with or substituted into the ENM surface rather than the ENM on its own. The bio-molecule corona of seemingly identical ENM cores may undergo dynamic changes during their passage through different biological compartments; in other words, their biological effects are governed by this complex surface chemistry. We propose that understanding the fundamental characteristics of ENM underpinning their biological effects will provide a sound foundation with which to classify ENM according to their safety. Therefore, the overarching objective of this research is to provide a means to develop a safety classification of ENM based on an understanding of their interactions with living organisms at the molecular, cellular, and organism levels based on their material characteristics.'

Introduzione (Teaser)

Engineered nanomaterials (ENMs) are now ubiquitous, but safety studies have lagged behind technological developments. EU-funded research will establish an ENM safety classifier akin to material safety data sheets to ensure safety for humans and the environment.

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