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CATCH ME SIGNED

Characterizing Atrial fibrillation by Translating its Causes into Health Modifiers in the Elderly

Total Cost €

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EC-Contrib. €

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Partnership

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Project "CATCH ME" data sheet

The following table provides information about the project.

Coordinator
THE UNIVERSITY OF BIRMINGHAM 

Organization address
address: Edgbaston
city: BIRMINGHAM
postcode: B15 2TT
website: www.bham.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Total cost 4˙944˙773 €
 EC max contribution 4˙944˙773 € (100%)
 Programme 1. H2020-EU.3.1.1. (Understanding health, wellbeing and disease)
 Code Call H2020-PHC-2014-two-stage
 Funding Scheme /RIA
 Starting year 2015
 Duration (year-month-day) from 2015-05-01   to  2019-04-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    THE UNIVERSITY OF BIRMINGHAM UK (BIRMINGHAM) coordinator 1˙303˙366.00
2    UNIVERSITEIT MAASTRICHT NL (MAASTRICHT) participant 718˙187.00
3    KOMPETENZNETZ VORHOFFLIMMERN E.V. DE (Muenster) participant 567˙500.00
4    LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN DE (MUENCHEN) participant 562˙000.00
5    THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD UK (OXFORD) participant 499˙803.00
6    CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER ES (BARCELONA) participant 462˙500.00
7    SOCIETE EUROPEENNE DE CARDIOLOGIE FR (BIOT SOPHIA ANTIPOLIS) participant 397˙037.00
8    SORBONNE UNIVERSITE FR (PARIS) participant 383˙367.00
9    THE UK HEALTH & ENVIRONMENT RESEARCH INSTITUTE UK (MELTON MOWBRAY) participant 51˙011.00
10    UNIVERSITE PIERRE ET MARIE CURIE - PARIS 6 FR (PARIS) participant 0.00

Mappa

 Project objective

Atrial fibrillation (AF) is the most common cardiac arrhythmia, with a prevalence of 1.5-2% in European populations. By being a major cause of stroke, dementia, heart failure, and premature death, AF is a major threat to healthy ageing. Despite increasing knowledge on the diverse mechanisms that cause the AF substrate in individual patients, current strategies for prevention and therapy of AF remain largely unguided by mechanistic insights. As a result - with the exception of anticoagulation for the prevention of AF-related stroke – treatment of AF has thus far failed to improve patients’ outcome. The CATCH ME consortium will bridge the present disconnect between our understanding of the molecular and electrophysiological mechanisms of AF and the current unstructured approach to its prevention and treatment. The consortium combines clinical, molecular, ECG engineering, and biostatistical expertise, and has access to large sets of human biological material (atrial tissue and bloods samples) and carefully phenotyped patient populations. Together, we will identify and integrate the main drivers of prevalent and incident AF in patients, and validate new ECG- and blood based markers in well-characterized cohorts. The results of these investigations will provide a quantitative estimate of the prevalence and impact of new and established risk factors for AF in Europe and uncover potential new targets and strategies for the prevention and treatment of this arrhythmia. We will integrate these factors into a new clinical classification of AF that will be externally validated in two large patient cohorts, including response to current treatment strategies, and AF-related complications. In summary, CATCH ME will 1. Identify major AF-related modifiers of health in the elderly in Europe, 2. Develop clinical tools that have the potential of transforming the management of AF in individual patients, and 3. Inform future personalized strategies to prevent and treat AF in Europe.

 Work performed, outcomes and results:  advancements report(s) 

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The information about "CATCH ME" are provided by the European Opendata Portal: CORDIS opendata.

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