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EUthyroid

Towards the elimination of iodine deficiency and preventable thyroid-related diseases in Europe

Total Cost €

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EC-Contrib. €

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Partnership

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Project "EUthyroid" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITATSMEDIZIN GREIFSWALD KORPERSCHAFT DES OFFENTLICHEN RECHTS 

Organization address
address: FLEISCHMANNSTRASSE 8
city: GREIFSWALD
postcode: 17489
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Project website http://euthyroid.eu/
 Total cost 3˙375˙330 €
 EC max contribution 2˙999˙949 € (89%)
 Programme 1. H2020-EU.3.1.2. (Preventing disease)
 Code Call H2020-PHC-2014-two-stage
 Funding Scheme RIA
 Starting year 2015
 Duration (year-month-day) from 2015-06-01   to  2018-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITATSMEDIZIN GREIFSWALD KORPERSCHAFT DES OFFENTLICHEN RECHTS DE (GREIFSWALD) coordinator 572˙602.00
2    TERVEYDEN JA HYVINVOINNIN LAITOS FI (HELSINKI) participant 416˙623.00
3    UMIT- PRIVATE UNIVERSITAT FUER GESUNDHEITSWISSENSCHAFTEN, MEDIZINISCHEINFORMATIK UND TECHNIK GMBH AT (HALL IN TIROL) participant 398˙812.00
4    BIOLUTION GMBH AT (WIEN) participant 376˙276.00
5    REGION HOVEDSTADEN DK (HILLEROD) participant 272˙963.00
6    UNIVERSITY OF SURREY UK (GUILDFORD) participant 185˙338.00
7    ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM NL (ROTTERDAM) participant 178˙340.00
8    LATVIJAS UNIVERSITATE LV (RIGA) participant 109˙407.00
9    FUNDACION PRIVADA INSTITUTO DE SALUD GLOBAL BARCELONA ES (BARCELONA) participant 89˙607.00
10    PANEPISTIMIO PATRON EL (RIO PATRAS) participant 73˙805.00
11    HAVFORSKNINGSINSTITUTTET NO (BERGEN) participant 31˙506.00
12    UNIWERSYTET JAGIELLONSKI PL (KRAKOW) participant 22˙492.00
13    SOFIA UNIVERSITY ST KLIMENT OHRIDSKI BG (SOFIA) participant 21˙125.00
14    CENTRE FOR REGIONAL POLICY RESEARCH AND COOPERATION STUDIORUM ZDRUZENJE MK (SKOPJE) participant 20˙177.00
15    ENDOKRINOLOGICKY USTAV CZ (PRAHA NOVE MESTO) participant 20˙177.00
16    MINISTERIO DA DEFESA NACIONAL PT (LISBOA) participant 20˙177.00
17    THE QUEEN'S UNIVERSITY OF BELFAST UK (BELFAST) participant 20˙177.00
18    INSTITUT DE INVESTIGACIO EN CIENCIES DE LA SALUT GERMANS TRIAS I PUJOL ES (BADALONA BARCELONA) participant 20˙165.00
19    UNIVERZITETNI KLINICNI CENTER LJUBLJANA SI (LJUBLJANA) participant 19˙875.00
20    VASTRA GOTALANDS LANS LANDSTING SE (VANERSBORG) participant 17˙875.00
21    IODINE GLOBAL NETWORK CA (OTTAWA ON) participant 13˙973.00
22    UNIVERSITE LIBRE DE BRUXELLES BE (BRUXELLES) participant 11˙692.00
23    DEBRECENI EGYETEM HU (DEBRECEN) participant 11˙276.00
24    LANDSPITALI UNIVERSITY HOSPITAL IS (REYKJAVIK) participant 11˙276.00
25    CENTRE HOSPITALIER UNIVERSITAIRE DE TOULOUSE FR (TOULOUSE CEDEX 3) participant 11˙270.00
26    OU ENDOKRINOLOOGIAKESKUS EE (Tartu) participant 11˙270.00
27    UNIVERSITA DI PISA IT (PISA) participant 11˙270.00
28    UPPSALA UNIVERSITET SE (UPPSALA) participant 11˙270.00
29    KLINICKI BOLNICKI CENTAR SESTRE MILOSRDNICE USTANOVA HR (ZAGREB) participant 11˙125.00
30    THE HEBREW UNIVERSITY OF JERUSALEM IL (JERUSALEM) participant 8˙000.00
31    EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH CH (ZUERICH) participant 0.00
32    FUNDACIO CENTRE DE RECERCA EN EPIDEMIOLOGIA AMBIENTAL - CREAL ES (BARCELONA) participant 0.00
33    NASJONALT INSTITUTT FOR ENAERINGS-OG SJOMATFORSKNING NO (BERGEN) participant 0.00

Map

 Project objective

Despite the fact that iodine deficiency (ID) can easily be prevented by iodine fortification of table salt, industrial salt and cattle food, Europe belongs to the worst regions in terms of access to iodized salt and is seriously ID, resulting in the perpetuation of the single most important, preventable cause of brain damage. European ID is due to significant heterogeneity in prevention and monitoring programs, leading to inappropriate interventions, increased disease burden, health inequities and increased health care costs. Up to 360 Million European citizens are exposed to ID disorders. An effective European monitoring program is a crucial step towards eradication of ID disorders with significant benefits for European citizens and the sustainability of health care systems. The effects of ID in total cause tremendous, preventable costs in health care systems of affected regions.

The overall aim of EUthyroid is to evaluate ID prevention and monitoring programs in 24 European countries, to initiate capacity building for harmonized European ID prevention and monitoring programs, and to disseminate project outcomes for supporting measures on national and EU level in order to eradicate ID disorders in Europe. The project will position itself as international hub of current national initiatives in the attempt to coordinate and support existing national activities. EUthyroid will generate the first harmonized data set of ID resulting in the first valid map of iodine status in Europe. With a dedicated dissemination program about the unfavorable health outcomes of ID, EUthyroid will pave the way for a harmonized EU-wide regulation of iodination, a common approach to iodine and outcome monitoring and establish recommendations for scientists on how to monitor IDD prevention programs. The project aims to make Europe a benchmark for ID disorder prevention worldwide.

 Deliverables

List of deliverables.
Association between repeated UICr measurements and IQ established Documents, reports 2019-10-08 14:20:36
Joint European database prepared for combining national/or regional registry outcome data related to iodine status Documents, reports 2019-10-08 14:20:39
Statistical analyses of associations between registry based outcome variables and actual iodine status finalised Documents, reports 2019-10-08 14:20:42
Report on the identification of a best-practice model of IDD prevention available Documents, reports 2019-10-08 14:20:42
Iodine status assessed by repeated UIC measurements Documents, reports 2019-10-08 14:20:34
Training modules finalised on EUthyroid websites Documents, reports 2019-10-08 14:20:41
Tg as a risk biomarker of iodine deficiency in pregnancy for neurocognitive function of the offspring evaluated Documents, reports 2019-10-08 14:20:18
Web-based training and certification tools online Documents, reports 2019-06-05 14:14:40
Communication plan established Documents, reports 2019-06-05 14:14:39
Website published Documents, reports 2019-06-05 14:14:39
Infrastructure of the data transfer unit established Documents, reports 2019-06-05 14:14:40

Take a look to the deliverables list in detail:  detailed list of EUthyroid deliverables.

 Publications

year authors and title journal last update
List of publications.
2016 Henry Völzke, Philippe Caron, Lisbeth Dahl, João J. de Castro, Iris Erlund, Simona Gaberšček, Ingibjörg Gunnarsdottir, Alicja Hubalewska-Dydejczyk, Till Ittermann, Ludmila Ivanova, Borislav Karanfilski, Rehman M. Khattak, Zvonko Kusić, Peter Laurberg, John H. Lazarus, Kostas B. Markou, Rodrigo Moreno-Reyes, Endre V. Nagy, Robin P. Peeters, Valdis Pīrāgs, Ján Podoba, Margaret P. Rayman, Ursula Rochau, Uwe Siebert, Peter P. Smyth, Betina H. Thuesen, Aron Troen, Lluís Vila, Paolo Vitti, Vaclav Zamrazil, Michael B. Zimmermann
Ensuring Effective Prevention of Iodine Deficiency Disorders
published pages: 189-196, ISSN: 1050-7256, DOI: 10.1089/thy.2015.0543
Thyroid 26/2 2019-06-05
2017 Malgorzata Trofimiuk-Mudlner, Alicja Hubalewska-Dydejczyk
Iodine Deficiency and Iodine Prophylaxis in Pregnancy
published pages: 85-95, ISSN: 1872-2148, DOI: 10.2174/1872214811666170309151538
Recent Patents on Endocrine, Metabolic & Immune Drug Discovery 10/2 2019-06-05
2018 Deborah Levie, Tim I M Korevaar, Sarah C Bath, Albert Dalmau-Bueno, Mario Murcia, Mercedes Espada, Mariana Dineva, Jesús M Ibarluzea, Jordi Sunyer, Henning Tiemeier, Marisa Rebagliato, Margaret P Rayman, Robin P Peeters, Mònica Guxens
Thyroid Function in Early Pregnancy, Child IQ, and Autistic Traits: a Meta-analysis of Individual-participant Data
published pages: , ISSN: 0021-972X, DOI: 10.1210/jc.2018-00224
The Journal of Clinical Endocrinology & Metabolism 2019-06-05
2017 Layal Chaker, Tim I M Korevaar, Dimitris Rizopoulos, Tinh-Hai Collet, Henry Völzke, Albert Hofman, Nicolas Rodondi, Anne R Cappola, Robin P Peeters, Oscar H Franco
Defining Optimal Health Range for Thyroid Function Based on the Risk of Cardiovascular Disease
published pages: 2853-2861, ISSN: 0021-972X, DOI: 10.1210/jc.2017-00410
The Journal of Clinical Endocrinology & Metabolism 102/8 2019-06-05
2018 Till Ittermann, Simone Johner, Harald Below, Matthias Leiterer, Michael Thamm, Thomas Remer, Henry Völzke
Interlaboratory variability of urinary iodine measurements
published pages: 441-447, ISSN: 1434-6621, DOI: 10.1515/cclm-2017-0580
Clinical Chemistry and Laboratory Medicine (CCLM) 56/3 2019-06-05
2016 Sarah C Bath
The challenges of harmonising the iodine supply across Europe
published pages: , ISSN: 2213-8587, DOI: 10.1016/S2213-8587(16)30329-1
The Lancet Diabetes & Endocrinology 2019-06-05
2017 Bílek R, Horáková L, Goš R, Zamrazil V.
Thyroid disease in the Czech Republic: the EUthyroid project and the evaluation of the General Health Insurance Company epidemiological data for the period of 2012-2015
published pages: 548-554, ISSN: 0042-773X, DOI:
Vnitřní lékařství 63(9) 2019-06-05
2016 Sara Stinca, Maria Andersson, Sandra Weibel, Isabelle Aeberli-Herter, Ralph Fingerhut, Sueppong Gowachirapant, Sonja Y. Hess, Nidhi Jaiswal, Tomislav Jukić, Zvonko Kusic, Ngoako Solomon Mabapa, Ashwini Kumar Nepal, Teofilo O.L. San Luis, Jia Qing Zhen, Michael Bruce Zimmermann
Dried blood spot thyroglobulin as a biomarker of iodine status in pregnant women
published pages: jc.2016-2829, ISSN: 0021-972X, DOI: 10.1210/jc.2016-2829
The Journal of Clinical Endocrinology & Metabolism 2019-06-05
2017 Yaniv S. Ovadia, Jonathan E. Arbelle, Dov Gefel, Hadassah Brik, Tamar Wolf, Varda Nadler, Sandra Hunziker, Michael B. Zimmermann, Aron M. Troen
First Israeli National Iodine Survey Demonstrates Iodine Deficiency Among School-Aged Children and Pregnant Women
published pages: 1083-1091, ISSN: 1050-7256, DOI: 10.1089/thy.2017.0251
Thyroid 27/8 2019-06-05
2018 Line Tang Møllehave, Allan Linneberg, Tea Skaaby, Nils Knudsen, Lars Ehlers, Torben Jørgensen, Betina Heinsbæk Thuesen
Trends in Costs of Thyroid Disease Treatment in Denmark during 1995–2015
published pages: 75-83, ISSN: 2235-0640, DOI: 10.1159/000485973
European Thyroid Journal 7/2 2019-06-05
2017 Lazarus JH
Relevance of iodine nutrition to health in the 21st century
published pages: 114-5, ISSN: 0026-4806, DOI: 10.23736/S0026-4806.17.05030-3
Minerva Medica 108(2) 2019-06-05
2016 Rehman Mehmood Khattak, Till Ittermann, Matthias Nauck, Harald Below, Henry Völzke
Monitoring the prevalence of thyroid disorders in the adult population of Northeast Germany
published pages: , ISSN: 1478-7954, DOI: 10.1186/s12963-016-0111-3
Population Health Metrics 14/1 2019-06-05
2015 Sara Stinca, Maria Andersson, Jürgen Erhardt, Michael B. Zimmermann
Development and Validation of a New Low-Cost Enzyme-Linked Immunoassay for Serum and Dried Blood Spot Thyroglobulin
published pages: 1297-1305, ISSN: 1050-7256, DOI: 10.1089/thy.2015.0428
Thyroid 25/12 2019-06-05
2016 Eftychia G. Koukkou, Ioannis Ilias, Irene Mamalis, Kostas B. Markou
Pregnant Greek Women May Have a Higher Prevalence of Iodine Deficiency than the General Greek Population
published pages: , ISSN: 2235-0640, DOI: 10.1159/000449285
European Thyroid Journal 2019-06-05
2016 Manousou S, Dahl L, Thuesen BH, Hulthén L, Filipsson HN.
Iodine deficiency and nutrition in Scandinavia
published pages: , ISSN: 0026-4806, DOI: 10.23736/S0026-4806.16.04849-7
Minerva Medica 2019-06-05
2017 Zamrazil V, Bílek R, Horáková L, Goš R
Changes in the incidence of thyroid disorders in the Czech Republic according to the VZP Registry in the period 2012-2015.
published pages: , ISSN: 0032-6739, DOI:
Praktický lékař 2019-06-05

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