Opendata, web and dolomites

LysoMod SIGNED

Genetic and Small Molecule Modifiers of Lysosomal Function

Total Cost €

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EC-Contrib. €

0

Partnership

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 LysoMod project word cloud

Explore the words cloud of the LysoMod project. It provides you a very rough idea of what is the project "LysoMod" about.

rnas    human    medicine    complementary    lysosomal    neurodegenerative    academic    prioritising    innovative    quality    preparing    lsd    mouse    sectors    implementing    life    function    therapies    genes    disorders    pathology    expertise    chemistry    young    training    biochemistry    drugs    public    diagnostics    expression    modifier    mentored    pioneer    talk    private    genetics    therapeutic    lysosome    strategies    age    variety    clinical    biological    innovate    led    collaborative    action    pharmacology    dysfunction    linked    ranging    cross    regulation    approved    lysomod    either    play    personalized    people    optimize    staff    companies    health    biomedical    lysosomes    mechanisms    transfer    lipidomics    exploring    critical    lsds    diseases    trials    area    disorder    generation    cell    rapid    cells    biology    participant    signalling    medicinal    storage    transcriptomics    drug    proteomics    candidate    careers    gene    exchange    multidisciplinary   

Project "LysoMod" data sheet

The following table provides information about the project.

Coordinator
INSTITUTO DE MEDICINA MOLECULAR JOAO LOBO ANTUNES 

Organization address
address: AVENIDA PROF EGAS MONIZ
city: LISBOA
postcode: 1649 028
website: www.imm.ul.pt

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Portugal [PT]
 Project website https://lysomod.wixsite.com/lysomod
 Total cost 1˙156˙500 €
 EC max contribution 1˙102˙500 € (95%)
 Programme 1. H2020-EU.1.3.3. (Stimulating innovation by means of cross-fertilisation of knowledge)
 Code Call H2020-MSCA-RISE-2016
 Funding Scheme MSCA-RISE
 Starting year 2017
 Duration (year-month-day) from 2017-03-01   to  2021-02-28

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    INSTITUTO DE MEDICINA MOLECULAR JOAO LOBO ANTUNES PT (LISBOA) coordinator 366˙300.00
2    GENOMED, DIAGNOSTICOS DE MEDICINA MOLECULAR SA PT (LISBOA) participant 240˙750.00
3    THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD UK (OXFORD) participant 198˙000.00
4    INSTITUTUL DE BIOCHIMIE RO (BUCHAREST) participant 130˙500.00
5    CHRONOS BIOSYSTEMS SRL RO (Bucharest) participant 108˙000.00
6    INTRABIO LTD UK (LONDON) participant 27˙000.00
7    WEIZMANN INSTITUTE OF SCIENCE IL (REHOVOT) participant 18˙450.00
8    THE UNIVERSITY OF SUSSEX UK (BRIGHTON) participant 13˙500.00
9    FONDAZIONE TELETHON IT (ROMA) participant 0.00
10    LIPOTYPE DE (DRESDEN) participant 0.00
11    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE CL (SANTIAGO) partner 0.00
12    THE CHILDREN'S HOSPITAL OF PHILADELPHIA NON PROFIT ORG US (Philadelphia) partner 0.00
13    UNIVERSIDAD DE BUENOS AIRES AR (BUENOS AIRES) partner 0.00
14    UNIVERSIDAD DEL DESARROLLO CL (SAN CARLOS DE APOQUINDO) partner 0.00

Map

 Project objective

LysoMod will innovate in the area of personalized medicine for disorders linked to lysosomal dysfunction. This will be achieved by implementing a collaborative staff-exchange program between highly complementary and multidisciplinary academic and non-academic partners with expertise in pharmacology, medicinal chemistry, cell biology, biochemistry, mouse and human genetics, transcriptomics, proteomics and lipidomics. Based on the critical role that lysosomes play in cells, a better understanding of lysosomal function will have a major impact on human health, fostering the development of new strategies to improve quality of life for people affected by a variety of diseases, ranging from lysosomal storage diseases (LSDs) to age-related neurodegenerative disorders. LysoMod’s specific objectives are: 1) to develop and further optimize existing therapies for LSDs; 2) to identify new targets for personalized therapies for LSDs; and 3) to investigate the cross-talk between lysosomal function, signalling pathways and gene expression regulation. The pioneer work of a participant in the consortium led to the development of a drug that is approved for clinical use. LysoMod will i) investigate the mechanisms of action of this and other drugs in lysosome-related disorder; ii) identify modifier genes involved in LSD pathology and test their potential as new targets for personalized therapeutic approaches; iii) identify candidate RNAs that can be targeted to enhance lysosomal function. The companies in the consortium will ensure a rapid transfer of new knowledge into applications for diagnostics and clinical trials. Prioritising lysosomal dysfunction as a highly relevant biomedical problem, the LysoMod consortium will implement a mentored staff-exchange program to provide young researchers with high-level training in innovative approaches for exploring biological systems, preparing the next generation of researchers for careers either in the private or public health sectors.

 Deliverables

List of deliverables.
Organization of a summer school in Chile Other 2020-03-03 15:05:06
Project Website Internet-based social media Websites, patent fillings, videos etc. 2020-03-03 15:05:06

Take a look to the deliverables list in detail:  detailed list of LysoMod deliverables.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "LYSOMOD" project.

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Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

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The information about "LYSOMOD" are provided by the European Opendata Portal: CORDIS opendata.

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