Opendata, web and dolomites

LysoMod SIGNED

Genetic and Small Molecule Modifiers of Lysosomal Function

Total Cost €

0

EC-Contrib. €

0

Partnership

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 LysoMod project word cloud

Explore the words cloud of the LysoMod project. It provides you a very rough idea of what is the project "LysoMod" about.

life    generation    therapies    pioneer    lysosomal    diseases    cells    cross    optimize    critical    clinical    academic    genes    disorders    medicine    quality    exploring    innovate    expertise    private    either    cell    pathology    talk    health    disorder    storage    age    chemistry    led    biomedical    human    gene    biochemistry    variety    neurodegenerative    candidate    ranging    area    drugs    pharmacology    drug    strategies    complementary    collaborative    prioritising    modifier    genetics    staff    careers    multidisciplinary    mouse    rnas    lysosome    regulation    companies    signalling    preparing    personalized    approved    lsd    lsds    public    lipidomics    expression    medicinal    participant    implementing    action    biology    transcriptomics    diagnostics    proteomics    lysosomes    rapid    training    function    therapeutic    mentored    people    trials    transfer    biological    innovative    play    mechanisms    linked    sectors    exchange    dysfunction    young    lysomod   

Project "LysoMod" data sheet

The following table provides information about the project.

Coordinator
INSTITUTO DE MEDICINA MOLECULAR JOAO LOBO ANTUNES 

Organization address
address: AVENIDA PROF EGAS MONIZ
city: LISBOA
postcode: 1649 028
website: www.imm.ul.pt

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Portugal [PT]
 Project website https://lysomod.wixsite.com/lysomod
 Total cost 1˙156˙500 €
 EC max contribution 1˙102˙500 € (95%)
 Programme 1. H2020-EU.1.3.3. (Stimulating innovation by means of cross-fertilisation of knowledge)
 Code Call H2020-MSCA-RISE-2016
 Funding Scheme MSCA-RISE
 Starting year 2017
 Duration (year-month-day) from 2017-03-01   to  2021-02-28

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    INSTITUTO DE MEDICINA MOLECULAR JOAO LOBO ANTUNES PT (LISBOA) coordinator 366˙300.00
2    GENOMED, DIAGNOSTICOS DE MEDICINA MOLECULAR SA PT (LISBOA) participant 240˙750.00
3    THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD UK (OXFORD) participant 198˙000.00
4    INSTITUTUL DE BIOCHIMIE RO (BUCHAREST) participant 130˙500.00
5    CHRONOS BIOSYSTEMS SRL RO (Bucharest) participant 108˙000.00
6    INTRABIO LTD UK (LONDON) participant 27˙000.00
7    WEIZMANN INSTITUTE OF SCIENCE IL (REHOVOT) participant 18˙450.00
8    THE UNIVERSITY OF SUSSEX UK (BRIGHTON) participant 13˙500.00
9    FONDAZIONE TELETHON IT (ROMA) participant 0.00
10    LIPOTYPE DE (DRESDEN) participant 0.00
11    PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE CL (SANTIAGO) partner 0.00
12    THE CHILDREN'S HOSPITAL OF PHILADELPHIA NON PROFIT ORG US (Philadelphia) partner 0.00
13    UNIVERSIDAD DE BUENOS AIRES AR (BUENOS AIRES) partner 0.00
14    UNIVERSIDAD DEL DESARROLLO CL (SAN CARLOS DE APOQUINDO) partner 0.00

Map

 Project objective

LysoMod will innovate in the area of personalized medicine for disorders linked to lysosomal dysfunction. This will be achieved by implementing a collaborative staff-exchange program between highly complementary and multidisciplinary academic and non-academic partners with expertise in pharmacology, medicinal chemistry, cell biology, biochemistry, mouse and human genetics, transcriptomics, proteomics and lipidomics. Based on the critical role that lysosomes play in cells, a better understanding of lysosomal function will have a major impact on human health, fostering the development of new strategies to improve quality of life for people affected by a variety of diseases, ranging from lysosomal storage diseases (LSDs) to age-related neurodegenerative disorders. LysoMod’s specific objectives are: 1) to develop and further optimize existing therapies for LSDs; 2) to identify new targets for personalized therapies for LSDs; and 3) to investigate the cross-talk between lysosomal function, signalling pathways and gene expression regulation. The pioneer work of a participant in the consortium led to the development of a drug that is approved for clinical use. LysoMod will i) investigate the mechanisms of action of this and other drugs in lysosome-related disorder; ii) identify modifier genes involved in LSD pathology and test their potential as new targets for personalized therapeutic approaches; iii) identify candidate RNAs that can be targeted to enhance lysosomal function. The companies in the consortium will ensure a rapid transfer of new knowledge into applications for diagnostics and clinical trials. Prioritising lysosomal dysfunction as a highly relevant biomedical problem, the LysoMod consortium will implement a mentored staff-exchange program to provide young researchers with high-level training in innovative approaches for exploring biological systems, preparing the next generation of researchers for careers either in the private or public health sectors.

 Deliverables

List of deliverables.
Organization of a summer school in Chile Other 2020-03-03 15:05:06
Project Website Internet-based social media Websites, patent fillings, videos etc. 2020-03-03 15:05:06

Take a look to the deliverables list in detail:  detailed list of LysoMod deliverables.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "LYSOMOD" project.

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Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

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The information about "LYSOMOD" are provided by the European Opendata Portal: CORDIS opendata.

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