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PICCOLO SIGNED

Multimodal highly-sensitive PhotonICs endoscope for improved in-vivo COLOn Cancer diagnosis and clinical decision support

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

PICCOLO project word cloud

Explore the words cloud of the PICCOLO project. It provides you a very rough idea of what is the project "PICCOLO" about.

diagnosis tomography cancer animal intervention safe coherence cure tested grading worldwide lesions combined combining diagnostics functional generate piccolo diagnostic accurate instrumentation endoscope characterization permit additional resection endoscopy red biomarkers precise flag cancers optical multidisciplinary mpt tenth smes competitiveness infiltration oct team characterisation multimodal fluorescence photon margin room components lesion providers identification sensitivity structural interventions imaging 90 disease colon specificity companies biopsy efficient company proposes representative human models automatic clinical market leader decision leadership outstanding gastroenterologists significantly automated images techniques hybrid rate neoplastic photonics vivo colorectal situ chain detection innovative compact

Project "PICCOLO" data sheet

The following table provides information about the project.

Coordinator	FUNDACION TECNALIA RESEARCH & INNOVATION Organization address address: PARQUE CIENTIFICO Y TECNOLOGICO DE BIZKAIA, ASTONDO BIDEA, EDIFICIO 700 city: DERIO BIZKAIA postcode: 48160 website: www.tecnalia.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Spain [ES]
Project website	http://www.piccolo-project.eu/
Total cost	3˙997˙655 €
EC max contribution	3˙997˙655 € (100%)
Programme	1. H2020-EU.2.1.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Information and Communication Technologies (ICT))
Code Call	H2020-ICT-2016-1
Funding Scheme	RIA
Starting year	2017
Duration (year-month-day)	from 2017-01-01 to 2020-06-30

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	FUNDACION TECNALIA RESEARCH & INNOVATION FUNDACION TECNALIA RESEARCH & INNOVATION Organization address address: PARQUE CIENTIFICO Y TECNOLOGICO DE BIZKAIA, ASTONDO BIDEA, EDIFICIO 700 city: DERIO BIZKAIA postcode: 48160 website: www.tecnalia.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (DERIO BIZKAIA)	coordinator	683˙500.00
2	L4T-LIGHT4TECH SRL L4T-LIGHT4TECH SRL Organization address address: VIA DELLA CERNAIA 5 city: FIRENZE postcode: 50129 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (FIRENZE)	participant	501˙250.00
3	KARL STORZ GMBH & CO. KG KARL STORZ GMBH & CO. KG Organization address address: MITTELSTRASSE 8 city: TUTTLINGEN postcode: 78532 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (TUTTLINGEN)	participant	492˙500.00
4	UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK Organization address address: WESTERN ROAD city: Cork postcode: T12 YN60 website: www.ucc.ie contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IE (Cork)	participant	481˙337.00
5	FUNDACION CENTRO DE CIRUGIA DE MINIMA INVASION JESUS USON FUNDACION CENTRO DE CIRUGIA DE MINIMA INVASION JESUS USON Organization address address: CARRETERA NACIONAL 521 KM 41 8 city: CACERES postcode: 10071 website: www.ccmijesususon.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (CACERES)	participant	440˙450.00
6	LABORATORIO EUROPEO DI SPETTROSCOPIE NON LINEARI LABORATORIO EUROPEO DI SPETTROSCOPIE NON LINEARI Organization address address: Via Nello Carrara 1 city: Sesto-Fiorentino (FI) postcode: 50019 website: www.lens.unifi.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (Sesto-Fiorentino (FI))	participant	361˙500.00
7	M-SQUARED LASERS LIMITED M-SQUARED LASERS LIMITED Organization address address: VENTURE BUILDING 1 KELVIN CAMPUS MARYHILL ROAD WEST OF SCOTLAND SCIENCE PARK city: GLASGOW postcode: G20 0SP website: www.m2lasers.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (GLASGOW)	participant	358˙750.00
8	IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE Organization address address: SOUTH KENSINGTON CAMPUS EXHIBITION ROAD city: LONDON postcode: SW7 2AZ website: http://www.imperial.ac.uk/ contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (LONDON)	participant	358˙242.00
9	FUNDACION VASCA DE INNOVACION E INVESTIGACION SANITARIAS FUNDACION VASCA DE INNOVACION E INVESTIGACION SANITARIAS Organization address address: RONDA DE AZKUE,1 city: BARAKALDO postcode: 48902 website: http://www.bioef.org contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (BARAKALDO)	participant	320˙125.00

Map

Project objective

Colorectal cancer represents around one tenth of all cancers worldwide. Early and accurate diagnosis and precise intervention can increase cure rate up to 90%. Improved diagnostic techniques with enough sensitivity and specificity are required to allow in situ assessment, safe characterization and resection of lesions during clinical practice interventions. The multidisciplinary PICCOLO team proposes a new compact, hybrid and multimodal photonics endoscope based on Optical Coherence Tomography (OCT) and Multi-Photon Tomography (MPT) combined with novel red-flag fluorescence technology for in vivo diagnosis and clinical decision support. By combining the outstanding structural information from OCT with the precise functional information from MPT, this innovative endoscope will provide gastroenterologists immediate and detailed in situ identification of colorectal neoplastic lesions and facilitate accurate and reliable in vivo diagnostics, with additional, grading capabilities for colon cancer as well as in-situ lesion infiltration and margin assessment. With the development of compact instrumentation, the cost of the components and thus the system will be significantly reduced. Human representative animal models will be used to generate imaging biomarkers that allow automated detection, assessment and grading of disease. The developed system will be tested in operating room conditions.

The consortium comprises the whole value chain including pre-clinical and clinical partners, technology providers, photonics SMEs and endoscopy market leader company. The project will permit these companies to enhance their competitiveness and leadership in the diagnostics sector as well as exploiting new market opportunities. The new endoscope will significantly impact clinical practice allowing in vivo optical biopsy assessment via the automatic analysis of images allowing accurate and efficient characterisation of colorectal lesions.

Deliverables

List of deliverables.
Ethical use of data in health databases v1	Documents, reports	2020-01-20 16:07:01
Website, templates and social media	Websites, patent fillings, videos etc.	2020-01-20 16:07:01
Promotional material	Websites, patent fillings, videos etc.	2020-01-20 16:07:01

Take a look to the deliverables list in detail: detailed list of PICCOLO deliverables.

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The information about "PICCOLO" are provided by the European Opendata Portal: CORDIS opendata.