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ZIKAVAX SIGNED

Fast track development of a Zika vaccine based on measles vector

Total Cost €

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EC-Contrib. €

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Partnership

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 ZIKAVAX project word cloud

Explore the words cloud of the ZIKAVAX project. It provides you a very rough idea of what is the project "ZIKAVAX" about.

world    issue    track    yield    health    virus    epidemiological    measles    candidate    variety    therapies    vector    diseases    treatments    safe    preventive    urgent    clinical    platform    standard    innovative    public    pasteur    trial    institut    flavivirus    proof    brain    congenital    purity    pathogens    demonstrated    neurological    vaccines    unaffected    affordable    nor    volunteers    borns    safety    consequently    mosquito    infection    infectious    outbreak    mice    spread    humans    record    adults    adult    previously    adaptability    date    agrave    vaccine    themis    malformations    immunisation    expression    atomique    bioscience    model    severe    antigen    zika    give    declared    immunogenicity    preclinical    disease    recombinant    demonstration    organization    truly    complications    primates    ia    effectiveness    ultimate    commissariat    zikavax    manufacturing    regions    1947    emergency    isolated    borne    energie    rapid    committed    human   

Project "ZIKAVAX" data sheet

The following table provides information about the project.

Coordinator
EUROPEAN VACCINE INITIATIVE EWIV 

Organization address
address: VOSSSTRASSE 2 GEB 4040
city: HEIDELBERG
postcode: 69115
website: http://www.euvaccine.eu/

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Project website http://www.zikavax.eu
 Total cost 4˙918˙137 €
 EC max contribution 4˙918˙137 € (100%)
 Programme 1. H2020-EU.3.1.2. (Preventing disease)
 Code Call H2020-SC1-2016-RTD
 Funding Scheme RIA
 Starting year 2016
 Duration (year-month-day) from 2016-10-01   to  2020-09-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    EUROPEAN VACCINE INITIATIVE EWIV DE (HEIDELBERG) coordinator 673˙968.00
2    THEMIS BIOSCIENCE GMBH AT (WIEN) participant 3˙192˙862.00
3    INSTITUT PASTEUR FR (PARIS CEDEX 15) participant 562˙290.00
4    COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES FR (PARIS 15) participant 489˙016.00

Map

 Project objective

Zika virus is an emerging mosquito-borne flavivirus. Although already isolated in 1947, to date there are no specific treatments nor any vaccines available against Zika virus disease, making it a truly neglected infectious disease. The recent rapid spread of the Zika virus in previously unaffected regions has provided strong epidemiological evidence that infection with this virus might be associated with neurological complications in adults and with an increase in severe congenital brain malformations of new-borns. Consequently, the World Health Organization has declared the recent outbreak of the Zika virus a public health emergency. The ZIKAVAX proposal has the objective to address this urgent public health issue by promoting the rapid development of a safe, effective, and affordable preventive vaccine against Zika virus infection. To achieve this goal, ZIKAVAX will use a delivery platform technology based on a measles vaccine vector with demonstrated proof of principle in humans and a preclinical track record of rapid adaptability and effectiveness for a variety of pathogens. The manufacturing process for these measles vector-based vaccines has been developed to give high yield and purity using standard equipment. In ZIKAVAX, following antigen selection and expression, immunisation studies will be conducted with the Zika vaccine candidate in mice and in a challenge model in non-human primates that will developed by the consortium. The ultimate goal of ZIKAVAX is the demonstration of safety and immunogenicity of a recombinant measles-Zika vaccine candidate in adult volunteers in a phase Ia clinical trial. ZIKAVAX is driven by a strongly committed and effective consortium of four leading European organisations highly experienced in vaccine research and development. Its partners include the European Vaccine Initiative, Institut Pasteur, Themis Bioscience GmbH and the Institute of Emerging Diseases and Innovative Therapies from the Commissariat à l’Energie Atomique.

 Deliverables

List of deliverables.
Launch of the website Websites, patent fillings, videos etc. 2019-05-30 15:16:10

Take a look to the deliverables list in detail:  detailed list of ZIKAVAX deliverables.

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The information about "ZIKAVAX" are provided by the European Opendata Portal: CORDIS opendata.

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