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ZIKAVAX SIGNED

Fast track development of a Zika vaccine based on measles vector

Total Cost €

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EC-Contrib. €

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Partnership

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 ZIKAVAX project word cloud

Explore the words cloud of the ZIKAVAX project. It provides you a very rough idea of what is the project "ZIKAVAX" about.

therapies    purity    safe    atomique    primates    organization    standard    immunogenicity    public    preventive    outbreak    issue    ultimate    consequently    virus    commissariat    severe    candidate    trial    mosquito    congenital    zika    diseases    antigen    flavivirus    clinical    model    treatments    health    borne    demonstration    brain    vaccines    agrave    humans    measles    declared    mice    zikavax    volunteers    manufacturing    urgent    give    platform    malformations    themis    regions    vaccine    energie    yield    effectiveness    human    neurological    innovative    pathogens    safety    spread    isolated    infectious    emergency    unaffected    previously    demonstrated    record    complications    adult    variety    1947    expression    nor    world    infection    pasteur    adults    bioscience    preclinical    vector    rapid    committed    truly    institut    immunisation    affordable    date    borns    epidemiological    disease    track    recombinant    proof    ia    adaptability   

Project "ZIKAVAX" data sheet

The following table provides information about the project.

Coordinator
EUROPEAN VACCINE INITIATIVE EWIV 

Organization address
address: VOSSSTRASSE 2 GEB 4040
city: HEIDELBERG
postcode: 69115
website: http://www.euvaccine.eu/

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Project website http://www.zikavax.eu
 Total cost 4˙918˙137 €
 EC max contribution 4˙918˙137 € (100%)
 Programme 1. H2020-EU.3.1.2. (Preventing disease)
 Code Call H2020-SC1-2016-RTD
 Funding Scheme RIA
 Starting year 2016
 Duration (year-month-day) from 2016-10-01   to  2020-09-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    EUROPEAN VACCINE INITIATIVE EWIV DE (HEIDELBERG) coordinator 673˙968.00
2    THEMIS BIOSCIENCE GMBH AT (WIEN) participant 3˙192˙862.00
3    INSTITUT PASTEUR FR (PARIS CEDEX 15) participant 562˙290.00
4    COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES FR (PARIS 15) participant 489˙016.00

Map

 Project objective

Zika virus is an emerging mosquito-borne flavivirus. Although already isolated in 1947, to date there are no specific treatments nor any vaccines available against Zika virus disease, making it a truly neglected infectious disease. The recent rapid spread of the Zika virus in previously unaffected regions has provided strong epidemiological evidence that infection with this virus might be associated with neurological complications in adults and with an increase in severe congenital brain malformations of new-borns. Consequently, the World Health Organization has declared the recent outbreak of the Zika virus a public health emergency. The ZIKAVAX proposal has the objective to address this urgent public health issue by promoting the rapid development of a safe, effective, and affordable preventive vaccine against Zika virus infection. To achieve this goal, ZIKAVAX will use a delivery platform technology based on a measles vaccine vector with demonstrated proof of principle in humans and a preclinical track record of rapid adaptability and effectiveness for a variety of pathogens. The manufacturing process for these measles vector-based vaccines has been developed to give high yield and purity using standard equipment. In ZIKAVAX, following antigen selection and expression, immunisation studies will be conducted with the Zika vaccine candidate in mice and in a challenge model in non-human primates that will developed by the consortium. The ultimate goal of ZIKAVAX is the demonstration of safety and immunogenicity of a recombinant measles-Zika vaccine candidate in adult volunteers in a phase Ia clinical trial. ZIKAVAX is driven by a strongly committed and effective consortium of four leading European organisations highly experienced in vaccine research and development. Its partners include the European Vaccine Initiative, Institut Pasteur, Themis Bioscience GmbH and the Institute of Emerging Diseases and Innovative Therapies from the Commissariat à l’Energie Atomique.

 Deliverables

List of deliverables.
Launch of the website Websites, patent fillings, videos etc. 2019-05-30 15:16:10

Take a look to the deliverables list in detail:  detailed list of ZIKAVAX deliverables.

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The information about "ZIKAVAX" are provided by the European Opendata Portal: CORDIS opendata.

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