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DENOCS SIGNED

The Double Edged Role of Nitric Oxide and Hydrogen Peroxide in a Coral Symbiosis

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 DENOCS project word cloud

Explore the words cloud of the DENOCS project. It provides you a very rough idea of what is the project "DENOCS" about.

oxide    experiencing    bleaching    physiological    symbiotic    lack    bioimaging    symbiont    hotspots    worldwide    h2o2    experimental    threshold    interdisciplinary    expert    partly    break    valuable    nitrogen    career    oxidative    dynamics    quantification    climate    combination    excellence    oxygen    nitrosative    sites    photosynthesis    reactive    14c    intact    events    concentrations    dr    subjected    photosymbionts    innovation    2016    spatio    international    microsensors    sources    underlying    quantitative    chlorophyll    coral    cellular    scenarios    nitric    outcomes    isolated    mechanisms    environmental    techniques    mimicking    peroxide    restart    date    treatments    biodiversity    hydrogen    temporal    maternity    marine    tools    denocs    global    fluorescence    species    sinks    culture    tissue    compounds    inducing    fixation    corals    training    schrameyer    imaging    suite    interplay    assays    prospective    suitable    unclear    stress    dysfunction    reefs   

Project "DENOCS" data sheet

The following table provides information about the project.

Coordinator
KOBENHAVNS UNIVERSITET 

Organization address
address: NORREGADE 10
city: KOBENHAVN
postcode: 1165
website: www.ku.dk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Denmark [DK]
 Total cost 212˙194 €
 EC max contribution 212˙194 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2016
 Funding Scheme MSCA-IF-EF-CAR
 Starting year 2017
 Duration (year-month-day) from 2017-06-01   to  2019-07-01

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    KOBENHAVNS UNIVERSITET DK (KOBENHAVN) coordinator 212˙194.00

Map

 Project objective

Global climate changes affect coral reefs worldwide and these valuable marine biodiversity hotspots are increasingly experiencing a symbiotic dysfunction known as coral bleaching, where the global bleaching events in 2016 are the most significant to date. The underlying physiological mechanisms inducing the bleaching response remain unclear. It is known that cellular oxidative stress and reactive species such as nitric oxide (NO) and hydrogen peroxide (H2O2) are involved, but the sources and sinks of these compounds, their interplay and spatio-temporal dynamics have not been investigated in corals, partly due to lack of suitable experimental tools. The DENOCS projects will apply a suite of novel quantitative assessment techniques to investigate the dynamics and impact sites of NO and H2O2 in intact corals, coral tissue culture, and isolated photosymbionts when subjected to experimental treatments mimicking global change-induced environmental stress scenarios. This will encompass expert training of Dr. Schrameyer in the use of novel microsensors for NO and H2O2 in combination with advanced bioimaging of the oxidative and nitrosative stress response in corals, variable chlorophyll fluorescence imaging and cellular 14C-fixation assays to assess symbiont photosynthesis. Prospective outcomes of DENOCS include a better understanding of oxidative and nitrosative stress responses in corals, quantification of threshold concentrations and impact sites of reactive oxygen and nitrogen species, and how these are involved in the coral bleaching response. The project DENOCS will promote EU’s research and innovation excellence through its interdisciplinary measurement approach and international collaboration, and will enable the restart of a promising career of Dr. Schrameyer after a maternity break.

 Publications

year authors and title journal last update
List of publications.
2018 Maria Moßhammer, Verena Schrameyer, Peter Ø. Jensen, Klaus Koren, Michael Kühl
Extracellular hydrogen peroxide measurements using a flow injection system in combination with microdialysis probes – Potential and challenges
published pages: 111-123, ISSN: 0891-5849, DOI: 10.1016/j.freeradbiomed.2018.05.089
Free Radical Biology and Medicine 128 2019-08-30

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