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DENOCS SIGNED

The Double Edged Role of Nitric Oxide and Hydrogen Peroxide in a Coral Symbiosis

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 DENOCS project word cloud

Explore the words cloud of the DENOCS project. It provides you a very rough idea of what is the project "DENOCS" about.

14c    culture    tools    fluorescence    events    quantification    restart    quantitative    expert    techniques    partly    chlorophyll    experimental    environmental    nitric    training    worldwide    bleaching    global    h2o2    temporal    dr    underlying    imaging    schrameyer    date    tissue    cellular    maternity    excellence    sinks    unclear    coral    spatio    scenarios    inducing    international    2016    prospective    fixation    sources    oxygen    microsensors    corals    experiencing    mechanisms    biodiversity    reefs    photosynthesis    treatments    sites    oxidative    suite    innovation    oxide    climate    compounds    isolated    hydrogen    mimicking    break    nitrogen    outcomes    stress    marine    dynamics    assays    concentrations    suitable    dysfunction    interplay    photosymbionts    valuable    species    lack    peroxide    symbiotic    physiological    threshold    bioimaging    subjected    interdisciplinary    denocs    hotspots    nitrosative    intact    reactive    career    symbiont    combination   

Project "DENOCS" data sheet

The following table provides information about the project.

Coordinator
KOBENHAVNS UNIVERSITET 

Organization address
address: NORREGADE 10
city: KOBENHAVN
postcode: 1165
website: www.ku.dk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Denmark [DK]
 Total cost 212˙194 €
 EC max contribution 212˙194 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2016
 Funding Scheme MSCA-IF-EF-CAR
 Starting year 2017
 Duration (year-month-day) from 2017-06-01   to  2019-07-01

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    KOBENHAVNS UNIVERSITET DK (KOBENHAVN) coordinator 212˙194.00

Map

 Project objective

Global climate changes affect coral reefs worldwide and these valuable marine biodiversity hotspots are increasingly experiencing a symbiotic dysfunction known as coral bleaching, where the global bleaching events in 2016 are the most significant to date. The underlying physiological mechanisms inducing the bleaching response remain unclear. It is known that cellular oxidative stress and reactive species such as nitric oxide (NO) and hydrogen peroxide (H2O2) are involved, but the sources and sinks of these compounds, their interplay and spatio-temporal dynamics have not been investigated in corals, partly due to lack of suitable experimental tools. The DENOCS projects will apply a suite of novel quantitative assessment techniques to investigate the dynamics and impact sites of NO and H2O2 in intact corals, coral tissue culture, and isolated photosymbionts when subjected to experimental treatments mimicking global change-induced environmental stress scenarios. This will encompass expert training of Dr. Schrameyer in the use of novel microsensors for NO and H2O2 in combination with advanced bioimaging of the oxidative and nitrosative stress response in corals, variable chlorophyll fluorescence imaging and cellular 14C-fixation assays to assess symbiont photosynthesis. Prospective outcomes of DENOCS include a better understanding of oxidative and nitrosative stress responses in corals, quantification of threshold concentrations and impact sites of reactive oxygen and nitrogen species, and how these are involved in the coral bleaching response. The project DENOCS will promote EU’s research and innovation excellence through its interdisciplinary measurement approach and international collaboration, and will enable the restart of a promising career of Dr. Schrameyer after a maternity break.

 Publications

year authors and title journal last update
List of publications.
2018 Maria Moßhammer, Verena Schrameyer, Peter Ø. Jensen, Klaus Koren, Michael Kühl
Extracellular hydrogen peroxide measurements using a flow injection system in combination with microdialysis probes – Potential and challenges
published pages: 111-123, ISSN: 0891-5849, DOI: 10.1016/j.freeradbiomed.2018.05.089
Free Radical Biology and Medicine 128 2019-08-30

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