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MEMENTO

MEMory processing in the human ENTOrhinal cortex

Total Cost €

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EC-Contrib. €

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Partnership

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Project "MEMENTO" data sheet

The following table provides information about the project.

Coordinator
THE UNIVERSITY OF BIRMINGHAM 

Organization address
address: Edgbaston
city: BIRMINGHAM
postcode: B15 2TT
website: www.bham.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Project website https://www.staresinalab.com/heidrun
 Total cost 183˙454 €
 EC max contribution 183˙454 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2016
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2017
 Duration (year-month-day) from 2017-07-01   to  2019-06-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    THE UNIVERSITY OF BIRMINGHAM UK (BIRMINGHAM) coordinator 183˙454.00

Map

 Project objective

Deeply embedded in the medial temporal lobe (MTL) memory system, the entorhinal cortex (EC) is a small yet potentially key region for intact memory. While a series of recent ground-breaking findings in rodents point towards a pivotal role of EC in spatial navigation, thought of as an evolutionary precursor to memory, little is known about its precise contribution to episodic memory in humans. Building on preliminary evidence that EC subregions may be specialised for different stimulus types and/or different memory processes, MEMENTO proposes a systematic investigation of memory function in the human EC. The action combines state-of-the-art high-resolution and ultra-high field functional magnetic resonance imaging (fMRI) with advanced analysis techniques to assess how these EC subregions support material-specific memory processing on four levels of resolution: the laminar level, the subregion level, the system level, and the behavioural level. MEMENTO is highly collaborative: it brings together expertise of the ER (high-resolution fMRI of entorhinal cortex subregions), the host supervisor (functional dynamics of the MTL, advanced fMRI analysis), and the partner organisation (ultra-high field fMRI). Given that the EC is one of the first structures affected in Alzheimer’s disease, the project results have great potential to stimulate important clinical implications. The ER will advance her research profile through highly transferable experience not only with cutting-edge methods, but also with managing and engaging in scientific and public communicative events. This will qualify her to lead her own research group upon returning.

 Publications

year authors and title journal last update
List of publications.
2019 Heidrun Schultz, Roni Tibon, Karen F. LaRocque, Stephanie A. Gagnon, Anthony D. Wagner, Bernhard P. Staresina
Content tuning in the medial temporal lobe cortex: Voxels that perceive, retrieve
published pages: ENEURO.0291-19.2, ISSN: 2373-2822, DOI: 10.1523/eneuro.0291-19.2019
eneuro 2019-11-22

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