Explore the words cloud of the IMGENE project. It provides you a very rough idea of what is the project "IMGENE" about.
The following table provides information about the project.
|Coordinator Country||Denmark [DK]|
|Total cost||2˙068˙409 €|
|EC max contribution||2˙068˙409 € (100%)|
1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
|Duration (year-month-day)||from 2017-09-01 to 2021-08-31|
Take a look of project's partnership.
|1||KOBENHAVNS UNIVERSITET||DK (KOBENHAVN)||coordinator||580˙163.00|
|2||ASTRAZENECA AB||SE (SODERTAELJE)||participant||263˙659.00|
|3||ACADEMISCH ZIEKENHUIS LEIDEN||NL (LEIDEN)||participant||255˙374.00|
|4||MAX DELBRUECK CENTRUM FUER MOLEKULARE MEDIZIN IN DER HELMHOLTZ-GEMEINSCHAFT (MDC)||DE (BERLIN)||participant||249˙216.00|
|5||UNIVERSITAETSKLINIKUM FREIBURG||DE (FREIBURG)||participant||249˙216.00|
|6||INSTITUTO DE BIOLOGIA MOLECULAR E CELULAR-IBMC||PT (PORTO)||participant||238˙356.00|
|7||USTAV MOLEKULARNI GENETIKY AKADEMIE VED CESKE REPUBLIKY VEREJNA VYZKUMNA INSTITUCE||CZ (PRAHA 4)||participant||232˙422.00|
|8||Genetic Alliance||UK (LONDON)||partner||0.00|
|9||Millipore Sigma||US (Massachusetts)||partner||0.00|
|10||Taconic GmbH||DE (Cologne)||partner||0.00|
CRISPR genome editing technology is considered to become the greatest technological improvement in biomedical research since the invention of the polymerase chain reaction 25 years ago and pharmaceutical companies as well as academic research are eager to apply it. However, the efficiency of introducing defined changes into the genome by CRISPR is still low, currently limiting its application in basic research, industry and gene therapy. IMGENE unites expert European research groups of academia and industry to address by innovative and complementary approaches the low efficiency of precise genome editing using CRISPR technology. To our best knowledge, IMGENE is the only concerted approach to tackle the important problem of low genome editing efficiency of CRISPR in a multidisciplinary, intersectorial manner. The IMGENE consortium consisting of 6 academic and 1 industrial beneficiary (AstraZeneca), 2 industrial partners (Taconic; MilliporeSigma), and the patient organization Genetic Alliance, aims to improve the genome editing efficiency of CRISPR by research training of 8 ESRs to unleash the full potential of this technology. Combining complementary knowledge on protein chemistry, molecular biology, cellular biology, viral vectors, transgenic mice, gene therapy, and bioinformatics present in the network, IMGENE will establish novel tools and protocols for improved CRISPR genome editing efficiency that will be of immediate benefit for health and life science research, the pharmaceutical industry, and the application of gene therapy. In addition, IMGENE addresses crucial ethical questions related to the application of genome editing technology in animals, plants, and humans, which have to be solved to gain acceptance by the society. By excellent research training of 8 ESRs on a scientifically and economically highly relevant topic and additional training in transferable skills, IMGENE will educate novel leaders with great career perspectives in industry and academia.
|year||authors and title||journal||last update|
Xiaoyu Chen, Francesca Tasca, Qian Wang, Jin Liu, Josephine M Janssen, Marcella D Brescia, Milena Bellin, Karoly Szuhai, Josefin Kenrick, Richard L Frock, Manuel A F V GonÃ§alves
Expanding the editable genome and CRISPRâ€“Cas9 versatility using DNA cutting-free gene targeting based on in trans paired nicking
published pages: , ISSN: 0305-1048, DOI: 10.1093/nar/gkz1121
|Nucleic Acids Research||2020-01-30|
Are you the coordinator (or a participant) of this project? Plaese send me more information about the "IMGENE" project.
For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.
Send me an email (email@example.com) and I put them in your project's page as son as possible.
Thanks. And then put a link of this page into your project's website.
The information about "IMGENE" are provided by the European Opendata Portal: CORDIS opendata.
Interdisciplinary connectivity: Understanding and managing complex systems using connectivity scienceRead More
Cultural Heritage Analysis for New GEnerationsRead More
Supporting the interaction of Humans and Automated vehicles: Preparing for the EnvIronment of TomorrowRead More