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SiNBioSys SIGNED

Luminescent silicon nanocrystals as bioimaging systems

Total Cost €

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EC-Contrib. €

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Partnership

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 SiNBioSys project word cloud

Explore the words cloud of the SiNBioSys project. It provides you a very rough idea of what is the project "SiNBioSys" about.

with    subsequently    nanocrystals    lifetime    photosi    diseases    techniques    easily    hundreds    tools    tool    material    investment    usa    patent    visualization    light    innovative    premises    contrast    images    diagnosis    expensive    tissues    companies    demonstrations    primary    biological    fluorescent    infrared    linked    tunability    excitation    brightness    realistic    replace    si    suffer    biocompatible    covalently    erc    sufficient    filed    optimization    purpose    utilise    sinbiosys    business    underlying    cells    intended    luminescence    neuroscience    social    dynamic    near    powerful    silicon    detection    market    probes    toxic    alternative    colour    hybrid    gated    coupled    markets    cancer    extraordinary    time    functions    region    benefits    penetration    microseconds    setups    attractive    commercial    surgery    sincs    nationalized    international    economic    lived    standards    abundant    exhibits    visible    imaging    scattering    improves    gather    guided    tissue    optical    gold    essentially    validation    dyes    strategy    2015   

Project "SiNBioSys" data sheet

The following table provides information about the project.

Coordinator
ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA 

Organization address
address: VIA ZAMBONI 33
city: BOLOGNA
postcode: 40126
website: www.unibo.it

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Italy [IT]
 Total cost 149˙937 €
 EC max contribution 149˙937 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2017-PoC
 Funding Scheme ERC-POC
 Starting year 2017
 Duration (year-month-day) from 2017-11-01   to  2019-04-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA IT (BOLOGNA) coordinator 149˙937.00

Map

 Project objective

Optical imaging is a powerful tool for light-guided surgery and for the study of biological functions via dynamic visualization of processes in tissues and cells. Most of optical imaging techniques utilise fluorescent probes that can suffer from low contrast, due to scattering of the excitation light, and low tissue penetration. Silicon nanocrystals (SiNCs), developed within the ERC PhotoSi project, are a very promising alternative for this purpose: silicon is essentially non-toxic, easily available, and it can be covalently linked with dyes. The result is a highly-robust and biocompatible hybrid material, which exhibits colour tunability across the visible and near-infrared region. On top of that, the extraordinary brightness of the material coupled to a long-lived luminescence (lifetime of the hundreds of microseconds) enables time-gated detection. Therefore, SiNBioSys technology greatly improves the contrast of the obtained images with a low-cost equipment and with a material based on abundant and biocompatible elements (Si, C, O, H). An international patent application on the key underlying technology was filed in 2015 and subsequently nationalized in the primary markets (Europe and USA). Based on these premises, this proposal is intended to gather sufficient technical and commercial evidence to make the SiNBioSys technology attractive for further investment in the development of a new commercial product by: (i) optimization and validation of SiNCs against current gold standards; (ii) an in-depth market analysis; (iii) a realistic business development strategy with demonstrations to leading companies in the field. The proposed technology will thus bring an economic impact, as well as social benefits: it will demonstrate its ability to replace currently used expensive setups and will enable innovative imaging tools for early diagnosis of diseases, particularly in the field of cancer and neuroscience.

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The information about "SINBIOSYS" are provided by the European Opendata Portal: CORDIS opendata.

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