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SiNBioSys SIGNED

Luminescent silicon nanocrystals as bioimaging systems

Total Cost €

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EC-Contrib. €

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Partnership

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 SiNBioSys project word cloud

Explore the words cloud of the SiNBioSys project. It provides you a very rough idea of what is the project "SiNBioSys" about.

visualization    light    social    erc    luminescence    guided    utilise    investment    scattering    time    replace    expensive    functions    primary    essentially    tissue    patent    international    contrast    infrared    gather    sincs    benefits    market    premises    si    cells    filed    intended    material    suffer    purpose    easily    biological    tool    attractive    strategy    with    extraordinary    toxic    covalently    2015    excitation    probes    biocompatible    visible    usa    region    exhibits    imaging    lifetime    underlying    penetration    optical    neuroscience    diagnosis    alternative    subsequently    microseconds    dyes    lived    techniques    gated    brightness    tissues    photosi    fluorescent    dynamic    hundreds    optimization    companies    colour    realistic    markets    near    innovative    coupled    detection    improves    nanocrystals    tools    linked    gold    business    abundant    diseases    economic    cancer    validation    sufficient    powerful    demonstrations    hybrid    tunability    nationalized    surgery    silicon    standards    setups    commercial    images    sinbiosys   

Project "SiNBioSys" data sheet

The following table provides information about the project.

Coordinator
ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA 

Organization address
address: VIA ZAMBONI 33
city: BOLOGNA
postcode: 40126
website: www.unibo.it

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Italy [IT]
 Total cost 149˙937 €
 EC max contribution 149˙937 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2017-PoC
 Funding Scheme ERC-POC
 Starting year 2017
 Duration (year-month-day) from 2017-11-01   to  2019-04-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA IT (BOLOGNA) coordinator 149˙937.00

Map

 Project objective

Optical imaging is a powerful tool for light-guided surgery and for the study of biological functions via dynamic visualization of processes in tissues and cells. Most of optical imaging techniques utilise fluorescent probes that can suffer from low contrast, due to scattering of the excitation light, and low tissue penetration. Silicon nanocrystals (SiNCs), developed within the ERC PhotoSi project, are a very promising alternative for this purpose: silicon is essentially non-toxic, easily available, and it can be covalently linked with dyes. The result is a highly-robust and biocompatible hybrid material, which exhibits colour tunability across the visible and near-infrared region. On top of that, the extraordinary brightness of the material coupled to a long-lived luminescence (lifetime of the hundreds of microseconds) enables time-gated detection. Therefore, SiNBioSys technology greatly improves the contrast of the obtained images with a low-cost equipment and with a material based on abundant and biocompatible elements (Si, C, O, H). An international patent application on the key underlying technology was filed in 2015 and subsequently nationalized in the primary markets (Europe and USA). Based on these premises, this proposal is intended to gather sufficient technical and commercial evidence to make the SiNBioSys technology attractive for further investment in the development of a new commercial product by: (i) optimization and validation of SiNCs against current gold standards; (ii) an in-depth market analysis; (iii) a realistic business development strategy with demonstrations to leading companies in the field. The proposed technology will thus bring an economic impact, as well as social benefits: it will demonstrate its ability to replace currently used expensive setups and will enable innovative imaging tools for early diagnosis of diseases, particularly in the field of cancer and neuroscience.

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The information about "SINBIOSYS" are provided by the European Opendata Portal: CORDIS opendata.

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