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Pharma-Factory SIGNED

Building the product pipeline for commercial demonstration of Plant Molecular Factories

Total Cost €

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EC-Contrib. €

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Partnership

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 Pharma-Factory project word cloud

Explore the words cloud of the Pharma-Factory project. It provides you a very rough idea of what is the project "Pharma-Factory" about.

designed    replacement    molecular    hiv    economic    evaluations    stakeholders    plants    factory    smes    vaccine    communication    infectious    potent    tools    companies    accelerate    arylsulfatase    hairy    commercialisation    biotechnology    neutralising    bio    industry    fish    engagement    social    fusion    competitiveness    diagnostic    virus    opportunity    academic    public    particles    veterinary    roots    culture    supporting    purpose    bottlenecks    antibody    government    refining    synthetic    life    manufacture    designing    regulatory    versatility    packages    parts    gain    kidney    acceptance    clear    techno    proteins    chimaeric    business    demonstrating    individual    manufacturing    resolving    collective    pharma    human    algae    cell    necrosis    biology    cycle    medical    understand    farming    scientists    technologies    conceived    plant    maximal    reduce    readiness    kit    enzyme    active    engaging    lifetime    barriers    utility    advantages    platforms    commercialized    platform    therapy    spleen    six    involvement    provides    consultation   

Project "Pharma-Factory" data sheet

The following table provides information about the project.

Coordinator
ST GEORGE'S HOSPITAL MEDICAL SCHOOL 

Organization address
address: CRANMER TERRACE
city: LONDON
postcode: SW17 0RE
website: http://www.sgul.ac.uk/

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Project website https://pharmafactory.org/
 Total cost 9˙254˙335 €
 EC max contribution 8˙286˙008 € (90%)
 Programme 1. H2020-EU.3.2.4.2. (Developing integrated biorefineries)
 Code Call H2020-BB-2017-1
 Funding Scheme IA
 Starting year 2017
 Duration (year-month-day) from 2017-11-01   to  2021-10-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    ST GEORGE'S HOSPITAL MEDICAL SCHOOL UK (LONDON) coordinator 1˙715˙885.00
2    FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. DE (MUNCHEN) participant 624˙547.00
3    Teknologian tutkimuskeskus VTT Oy FI (Espoo) participant 560˙827.00
4    UNIVERSITE DE ROUEN NORMANDIE FR (MONT SAINT AIGNAN CEDEX) participant 531˙500.00
5    UNIVERSITY COLLEGE LONDON UK (LONDON) participant 524˙226.00
6    THE UNIVERSITY OF THE ARTS LONDON UK (LONDON) participant 520˙000.00
7    UNIVERSIDAD DE LLEIDA ES (LLEIDA) participant 519˙902.00
8    TRANSALGAE ISRAEL LTD IL (TEHOVOT) participant 519˙750.00
9    AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS ES (MADRID) participant 519˙710.00
10    JOHN INNES CENTRE UK (NORWICH) participant 509˙982.00
11    DIAMANTE SRL IT (VERONA) participant 499˙625.00
12    SAMABRIVA FR (AMIENS) participant 455˙700.00
13    ALBAJUNA THERAPEUTICS ES (BADALONA) participant 400˙312.00
14    LEAF SYSTEMS INTERNATIONAL LIMITED UK (NORWICH) participant 384˙040.00

Map

 Project objective

Plant Molecular Farming is the manufacture of high-value products using plant biotechnology. Pharma-Factory was conceived and designed by SMEs active in the field to produce medical, veterinary and diagnostic products. Product-driven work packages and a collective approach to public involvement and regulatory consultation will accelerate commercialisation of new bio-products, and increase the competitiveness of European bio-industry by resolving technical, social and economic bottlenecks in this field. All parts of the work programme are addressed by refining technologies using new synthetic biology tools, demonstrating manufacturing advantages for individual products, identifying a clear regulatory path for each platform technology, developing clear business cases with supporting techno-economic evaluations and life cycle analyses and improving public engagement and acceptance. Five SMEs will develop products that include arylsulfatase B (for human enzyme replacement therapy), a vaccine for infectious spleen and kidney necrosis virus in fish, two highly potent HIV neutralising antibody-based fusion proteins and plant chimaeric virus-like-particles for a diagnostic kit. In collaboration with academic partners they will advance six plant molecular farming platforms for this purpose, including whole plants, algae, hairy roots and plant cell culture, by designing and developing new tools to increase the competitiveness, utility and versatility of each platform. All companies will reach Technology Readiness Level 5 within the lifetime of the project, with two products to be commercialized. The project provides a unique opportunity to improve public involvement with plant biotechnology at a European-wide level. A work package has been dedicated to gain maximal impact by engaging with all stakeholders – from scientists to government and the public at large, developing new tools to facilitate communication, to help understand and reduce barriers to acceptance.

 Deliverables

List of deliverables.
Project website Websites, patent fillings, videos etc. 2019-11-25 11:41:00

Take a look to the deliverables list in detail:  detailed list of Pharma-Factory deliverables.

 Publications

year authors and title journal last update
List of publications.
2018 Evangelia Vamvaka, Gemma Farré, Luis M. Molinos-Albert, Abbey Evans, Anna Canela-Xandri, Richard M. Twyman, Jorge Carrillo, Raziel A. Ordóñez, Robin J. Shattock, Barry R. O’Keefe, Bonaventura Clotet, Julian Blanco, Gurdev S. Khush, Paul Christou, Teresa Capell
Unexpected synergistic HIV neutralization by a triple microbicide produced in rice endosperm
published pages: E7854-E7862, ISSN: 0027-8424, DOI: 10.1073/pnas.1806022115
Proceedings of the National Academy of Sciences 115/33 2019-11-25

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The information about "PHARMA-FACTORY" are provided by the European Opendata Portal: CORDIS opendata.

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Pharma-Factory (2017)

Building the product pipeline for commercial demonstration of Plant Molecular Factories

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