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Pharma-Factory SIGNED

Building the product pipeline for commercial demonstration of Plant Molecular Factories

Total Cost €

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EC-Contrib. €

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Partnership

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Outcomes and
results

Pharma-Factory project word cloud

Explore the words cloud of the Pharma-Factory project. It provides you a very rough idea of what is the project "Pharma-Factory" about.

arylsulfatase advantages stakeholders parts fusion utility demonstrating pharma government therapy refining readiness bio gain six individual plant bottlenecks understand culture provides reduce manufacturing human cell versatility consultation accelerate lifetime algae potent platforms smes proteins manufacture purpose hairy regulatory infectious resolving vaccine conceived communication diagnostic engaging industry neutralising farming maximal collective competitiveness academic biology roots business platform involvement kidney technologies opportunity spleen techno plants synthetic commercialized life factory cycle hiv barriers packages biotechnology particles supporting engagement clear kit molecular veterinary replacement fish commercialisation tools virus active scientists acceptance designing social necrosis medical public chimaeric evaluations enzyme antibody economic designed companies

Project "Pharma-Factory" data sheet

The following table provides information about the project.

Coordinator	ST GEORGE'S HOSPITAL MEDICAL SCHOOL Organization address address: CRANMER TERRACE city: LONDON postcode: SW17 0RE website: http://www.sgul.ac.uk/ contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	United Kingdom [UK]
Project website	https://pharmafactory.org/
Total cost	9˙254˙335 €
EC max contribution	8˙286˙008 € (90%)
Programme	1. H2020-EU.3.2.4.2. (Developing integrated biorefineries)
Code Call	H2020-BB-2017-1
Funding Scheme	IA
Starting year	2017
Duration (year-month-day)	from 2017-11-01 to 2021-10-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	ST GEORGE'S HOSPITAL MEDICAL SCHOOL ST GEORGE'S HOSPITAL MEDICAL SCHOOL Organization address address: CRANMER TERRACE city: LONDON postcode: SW17 0RE website: http://www.sgul.ac.uk/ contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (LONDON)	coordinator	1˙715˙885.00
2	FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. Organization address address: HANSASTRASSE 27C city: MUNCHEN postcode: 80686 website: www.fraunhofer.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (MUNCHEN)	participant	624˙547.00
3	Teknologian tutkimuskeskus VTT Oy Teknologian tutkimuskeskus VTT Oy Organization address address: VUORIMIEHENTIE 3 city: Espoo postcode: 2150 website: www.vtt.fi contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FI (Espoo)	participant	560˙827.00
4	UNIVERSITE DE ROUEN NORMANDIE UNIVERSITE DE ROUEN NORMANDIE Organization address address: RUE THOMAS BECKET 1 MONT SAINT AIGNAN city: MONT SAINT AIGNAN CEDEX postcode: 76821 website: www.univ-rouen.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (MONT SAINT AIGNAN CEDEX)	participant	531˙500.00
5	UNIVERSITY COLLEGE LONDON UNIVERSITY COLLEGE LONDON Organization address address: GOWER STREET city: LONDON postcode: WC1E 6BT website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (LONDON)	participant	524˙226.00
6	THE UNIVERSITY OF THE ARTS LONDON THE UNIVERSITY OF THE ARTS LONDON Organization address address: 272 HIGH HOLBURN city: LONDON postcode: WC1V 7EY website: http://www.fashion.arts.ac.uk/index.htm contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (LONDON)	participant	520˙000.00
7	UNIVERSIDAD DE LLEIDA UNIVERSIDAD DE LLEIDA Organization address address: Placa Victor Siurana 1 1 city: LLEIDA postcode: 25003 website: www.udl.cat contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (LLEIDA)	participant	519˙902.00
8	TRANSALGAE ISRAEL LTD TRANSALGAE ISRAEL LTD Organization address address: 2 HAIM PEKERIS STREET city: TEHOVOT postcode: 7670202 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IL (TEHOVOT)	participant	519˙750.00
9	AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS Organization address address: CALLE SERRANO 117 city: MADRID postcode: 28006 website: http://www.csic.es contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (MADRID)	participant	519˙710.00
10	JOHN INNES CENTRE JOHN INNES CENTRE Organization address address: NORWICH RESEARCH PARK COLNEY city: NORWICH postcode: NR4 7UH website: www.jic.bbsrc.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (NORWICH)	participant	509˙982.00
11	DIAMANTE SRL DIAMANTE SRL Organization address address: STRADA LE GRAZIE 15 city: VERONA postcode: 37134 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (VERONA)	participant	499˙625.00
12	SAMABRIVA SAMABRIVA Organization address address: 72 RUE DES JACOBINS city: AMIENS postcode: 80000 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (AMIENS)	participant	455˙700.00
13	ALBAJUNA THERAPEUTICS ALBAJUNA THERAPEUTICS Organization address address: CTRA DEL CANYET, S/N, HOSPITAL GERMANS TRIAS I PUJOL, 2 PLANTA city: BADALONA postcode: 8916 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (BADALONA)	participant	400˙312.00
14	LEAF SYSTEMS INTERNATIONAL LIMITED LEAF SYSTEMS INTERNATIONAL LIMITED Organization address address: BUILDING 7, ZONE 2, NORWICH RESEARCH PARK, COLNEY LANE, COLNEY city: NORWICH postcode: NR47UJ website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (NORWICH)	participant	384˙040.00

Map

Project objective

Plant Molecular Farming is the manufacture of high-value products using plant biotechnology. Pharma-Factory was conceived and designed by SMEs active in the field to produce medical, veterinary and diagnostic products. Product-driven work packages and a collective approach to public involvement and regulatory consultation will accelerate commercialisation of new bio-products, and increase the competitiveness of European bio-industry by resolving technical, social and economic bottlenecks in this field. All parts of the work programme are addressed by refining technologies using new synthetic biology tools, demonstrating manufacturing advantages for individual products, identifying a clear regulatory path for each platform technology, developing clear business cases with supporting techno-economic evaluations and life cycle analyses and improving public engagement and acceptance. Five SMEs will develop products that include arylsulfatase B (for human enzyme replacement therapy), a vaccine for infectious spleen and kidney necrosis virus in fish, two highly potent HIV neutralising antibody-based fusion proteins and plant chimaeric virus-like-particles for a diagnostic kit. In collaboration with academic partners they will advance six plant molecular farming platforms for this purpose, including whole plants, algae, hairy roots and plant cell culture, by designing and developing new tools to increase the competitiveness, utility and versatility of each platform. All companies will reach Technology Readiness Level 5 within the lifetime of the project, with two products to be commercialized. The project provides a unique opportunity to improve public involvement with plant biotechnology at a European-wide level. A work package has been dedicated to gain maximal impact by engaging with all stakeholders – from scientists to government and the public at large, developing new tools to facilitate communication, to help understand and reduce barriers to acceptance.

Deliverables

List of deliverables.
Project website	Websites, patent fillings, videos etc.	2019-11-25 11:41:00

Take a look to the deliverables list in detail: detailed list of Pharma-Factory deliverables.

Publications

List of publications.
year	authors and title	journal	last update
2018	Evangelia Vamvaka, Gemma FarrÃ©, Luis M. Molinos-Albert, Abbey Evans, Anna Canela-Xandri, Richard M. Twyman, Jorge Carrillo, Raziel A. OrdÃ³Ã±ez, Robin J. Shattock, Barry R. Oâ€™Keefe, Bonaventura Clotet, Julian Blanco, Gurdev S. Khush, Paul Christou, Teresa Capell Unexpected synergistic HIV neutralization by a triple microbicide produced in rice endosperm published pages: E7854-E7862, ISSN: 0027-8424, DOI: 10.1073/pnas.1806022115	Proceedings of the National Academy of Sciences 115/33	2019-11-25

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The information about "PHARMA-FACTORY" are provided by the European Opendata Portal: CORDIS opendata.

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Pharma-Factory (2017)

Building the product pipeline for commercial demonstration of Plant Molecular Factories

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