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Pharma-Factory SIGNED

Building the product pipeline for commercial demonstration of Plant Molecular Factories

Total Cost €

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EC-Contrib. €

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Partnership

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 Pharma-Factory project word cloud

Explore the words cloud of the Pharma-Factory project. It provides you a very rough idea of what is the project "Pharma-Factory" about.

vaccine    commercialized    acceptance    roots    provides    gain    lifetime    evaluations    hairy    versatility    plants    collective    algae    culture    purpose    techno    industry    involvement    bio    manufacturing    farming    regulatory    understand    life    platforms    diagnostic    maximal    accelerate    technologies    business    tools    advantages    cell    spleen    infectious    hiv    pharma    manufacture    human    enzyme    parts    utility    conceived    refining    smes    designing    active    reduce    particles    chimaeric    social    kit    arylsulfatase    necrosis    readiness    opportunity    proteins    individual    communication    demonstrating    barriers    consultation    fusion    commercialisation    plant    fish    six    kidney    replacement    therapy    scientists    academic    clear    bottlenecks    cycle    companies    synthetic    government    biology    potent    platform    veterinary    neutralising    molecular    factory    virus    supporting    stakeholders    public    designed    economic    competitiveness    biotechnology    resolving    medical    engaging    engagement    antibody    packages   

Project "Pharma-Factory" data sheet

The following table provides information about the project.

Coordinator
ST GEORGE'S HOSPITAL MEDICAL SCHOOL 

Organization address
address: CRANMER TERRACE
city: LONDON
postcode: SW17 0RE
website: http://www.sgul.ac.uk/

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Project website https://pharmafactory.org/
 Total cost 9˙254˙335 €
 EC max contribution 8˙286˙008 € (90%)
 Programme 1. H2020-EU.3.2.4.2. (Developing integrated biorefineries)
 Code Call H2020-BB-2017-1
 Funding Scheme IA
 Starting year 2017
 Duration (year-month-day) from 2017-11-01   to  2021-10-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    ST GEORGE'S HOSPITAL MEDICAL SCHOOL UK (LONDON) coordinator 1˙715˙885.00
2    FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. DE (MUNCHEN) participant 624˙547.00
3    Teknologian tutkimuskeskus VTT Oy FI (Espoo) participant 560˙827.00
4    UNIVERSITE DE ROUEN NORMANDIE FR (MONT SAINT AIGNAN CEDEX) participant 531˙500.00
5    UNIVERSITY COLLEGE LONDON UK (LONDON) participant 524˙226.00
6    THE UNIVERSITY OF THE ARTS LONDON UK (LONDON) participant 520˙000.00
7    UNIVERSIDAD DE LLEIDA ES (LLEIDA) participant 519˙902.00
8    TRANSALGAE ISRAEL LTD IL (TEHOVOT) participant 519˙750.00
9    AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS ES (MADRID) participant 519˙710.00
10    JOHN INNES CENTRE UK (NORWICH) participant 509˙982.00
11    DIAMANTE SRL IT (VERONA) participant 499˙625.00
12    SAMABRIVA FR (AMIENS) participant 455˙700.00
13    ALBAJUNA THERAPEUTICS ES (BADALONA) participant 400˙312.00
14    LEAF SYSTEMS INTERNATIONAL LIMITED UK (NORWICH) participant 384˙040.00

Map

 Project objective

Plant Molecular Farming is the manufacture of high-value products using plant biotechnology. Pharma-Factory was conceived and designed by SMEs active in the field to produce medical, veterinary and diagnostic products. Product-driven work packages and a collective approach to public involvement and regulatory consultation will accelerate commercialisation of new bio-products, and increase the competitiveness of European bio-industry by resolving technical, social and economic bottlenecks in this field. All parts of the work programme are addressed by refining technologies using new synthetic biology tools, demonstrating manufacturing advantages for individual products, identifying a clear regulatory path for each platform technology, developing clear business cases with supporting techno-economic evaluations and life cycle analyses and improving public engagement and acceptance. Five SMEs will develop products that include arylsulfatase B (for human enzyme replacement therapy), a vaccine for infectious spleen and kidney necrosis virus in fish, two highly potent HIV neutralising antibody-based fusion proteins and plant chimaeric virus-like-particles for a diagnostic kit. In collaboration with academic partners they will advance six plant molecular farming platforms for this purpose, including whole plants, algae, hairy roots and plant cell culture, by designing and developing new tools to increase the competitiveness, utility and versatility of each platform. All companies will reach Technology Readiness Level 5 within the lifetime of the project, with two products to be commercialized. The project provides a unique opportunity to improve public involvement with plant biotechnology at a European-wide level. A work package has been dedicated to gain maximal impact by engaging with all stakeholders – from scientists to government and the public at large, developing new tools to facilitate communication, to help understand and reduce barriers to acceptance.

 Deliverables

List of deliverables.
Project website Websites, patent fillings, videos etc. 2019-11-25 11:41:00

Take a look to the deliverables list in detail:  detailed list of Pharma-Factory deliverables.

 Publications

year authors and title journal last update
List of publications.
2018 Evangelia Vamvaka, Gemma Farré, Luis M. Molinos-Albert, Abbey Evans, Anna Canela-Xandri, Richard M. Twyman, Jorge Carrillo, Raziel A. Ordóñez, Robin J. Shattock, Barry R. O’Keefe, Bonaventura Clotet, Julian Blanco, Gurdev S. Khush, Paul Christou, Teresa Capell
Unexpected synergistic HIV neutralization by a triple microbicide produced in rice endosperm
published pages: E7854-E7862, ISSN: 0027-8424, DOI: 10.1073/pnas.1806022115
Proceedings of the National Academy of Sciences 115/33 2019-11-25

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The information about "PHARMA-FACTORY" are provided by the European Opendata Portal: CORDIS opendata.

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Pharma-Factory (2017)

Building the product pipeline for commercial demonstration of Plant Molecular Factories

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