Opendata, web and dolomites

4-D nanoSCOPE SIGNED

Advancing osteoporosis medicine by observing bone microstructure and remodelling using a four-dimensional nanoscope

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 4-D nanoSCOPE project word cloud

Explore the words cloud of the 4-D nanoSCOPE project. It provides you a very rough idea of what is the project "4-D nanoSCOPE" about.

learning    breathing    considerable    dynamics    occurrence    age    impaired    strength    bone    resolved    creatures    microscopy    due    productivity    lack    imaging    remodeling    spatial    precision    revolutionizing    diseases    treatment    hormones    dimensional    life    transport    innovative    images    permitting    twitching    velocities    quality    osteoporosis    thoroughly    resolution    first    artefacts    sufferers    permit    sections    microscope    software    composition    dramatic    correlative    revolutionized    thereby    inflammation    injuries    serial    dimensions    spectroscopy    vitro    ex    living    chemical    microstructure    techniques    properly    image    pis    structure    disease    acquisition    datasets    local    monitoring    function    vascular    small    complemented    ray    consequent    speed    tools    vivo    collaborators    series    hardware    ing    compensate    time    international    hampered    society    subject    characterization    nanoscope    ageing    morphology    combining    animals    mice    op    4d   

Project "4-D nanoSCOPE" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITATSKLINIKUM ERLANGEN 

Organization address
address: MAXIMILIANSPLATZ 2
city: ERLANGEN
postcode: 91054
website: www.uk-erlangen.de

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Total cost 12˙366˙635 €
 EC max contribution 12˙366˙635 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2018-SyG
 Funding Scheme ERC-SyG
 Starting year 2019
 Duration (year-month-day) from 2019-04-01   to  2025-03-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITATSKLINIKUM ERLANGEN DE (ERLANGEN) coordinator 2˙837˙980.00
2    FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. DE (MUNCHEN) participant 6˙773˙605.00
3    FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN NUERNBERG DE (ERLANGEN) participant 2˙755˙050.00
4    HELMHOLTZ-ZENTRUM BERLIN FUR MATERIALIEN UND ENERGIE GMBH DE (BERLIN) participant 0.00

Map

 Project objective

Due to Europe's ageing society, there has been a dramatic increase in the occurrence of osteoporosis (OP) and related diseases. Sufferers have an impaired quality of life, and there is a considerable cost to society associated with the consequent loss of productivity and injuries. The current understanding of this disease needs to be revolutionized, but study has been hampered by a lack of means to properly characterize bone structure, remodeling dynamics and vascular activity. This project, 4D nanoSCOPE, will develop tools and techniques to permit time-resolved imaging and characterization of bone in three spatial dimensions (both in vitro and in vivo), thereby permitting monitoring of bone remodeling and revolutionizing the understanding of bone morphology and its function. To advance the field, in vivo high-resolution studies of living bone are essential, but existing techniques are not capable of this. By combining state-of-the art image processing software with innovative 'precision learning' software methods to compensate for artefacts (due e.g. to the subject breathing or twitching), and innovative X-ray microscope hardware which together will greatly speed up image acquisition (aim is a factor of 100), the project will enable in vivo X-ray microscopy studies of small animals (mice) for the first time. The time series of three-dimensional X-ray images will be complemented by correlative microscopy and spectroscopy techniques (with new software) to thoroughly characterize (serial) bone sections ex vivo. The resulting three-dimensional datasets combining structure, chemical composition, transport velocities and local strength will be used by the PIs and international collaborators to study the dynamics of bone microstructure. This will be the first time that this has been possible in living creatures, enabling an assessment of the effects on bone of age, hormones, inflammation and treatment.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "4-D NANOSCOPE" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "4-D NANOSCOPE" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.1.)

MOCHA (2019)

Understanding and leveraging ‘moments of change’ for pro-environmental behaviour shifts

Read More  

HyperBio (2019)

Vis-NIR Hyperspectral imaging for biomaterial quality control

Read More  

TechChange (2019)

Technological Change: New Sources, Consequences, and Impact Mitigation

Read More