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UNITI SIGNED

Unification of treatments and Interventions for Tinnitus patients

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 UNITI project word cloud

Explore the words cloud of the UNITI project. It provides you a very rough idea of what is the project "UNITI" about.

found    groups    health    subgroups    double    relevance    communication    attempting    trial    burden    predictive    gender    reached    uniti    genotyping    hyperactive       cohort    phenotyping    reflecting    68    extracted    close    causes    phantom    men    central    schizophrenia    time    nervous    analysed    issue    missing    reaction    economic    prevalence    highlighted    medical    predict    combinatorial    auditory    10    tested    estimates    deficit    patients    randomized    signals    bilateral    tends    consensus    autism    2050    computational    optimal    databases    ear    tinnitus    made    decades    data    therapies    poorly    perception    model    patient    clinical    enigma    itinnitus    prognostic    disorder    brain    longitudinal    correlate    assuming    sound    variety    aetiology    whereas    population    age    adhd    heritability    combination    progress    cure    undergo    older    rct    scientific    phenotype    genetic    epidemiological    audiological    question    treatment   

Project "UNITI" data sheet

The following table provides information about the project.

Coordinator
KLINIKUM DER UNIVERSITAET REGENSBURG 

Organization address
address: FRANS JOSEF STRAUSS ALLEE 11
city: REGENSBURG
postcode: 93053
website: www-cgi.uni-regensburg.de/Klinik/Klinikum/

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Total cost 5˙989˙343 €
 EC max contribution 5˙989˙343 € (100%)
 Programme 1. H2020-EU.3.1.1. (Understanding health, wellbeing and disease)
 Code Call H2020-SC1-2019-Two-Stage-RTD
 Funding Scheme RIA
 Starting year 2020
 Duration (year-month-day) from 2020-01-01   to  2023-03-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    KLINIKUM DER UNIVERSITAET REGENSBURG DE (REGENSBURG) coordinator 884˙948.00
2    SERVICIO ANDALUZ DE SALUD ES (SEVILLA) participant 696˙875.00
3    KAROLINSKA INSTITUTET SE (STOCKHOLM) participant 686˙645.00
4    CHARITE - UNIVERSITAETSMEDIZIN BERLIN DE (BERLIN) participant 499˙500.00
5    KATHOLIEKE UNIVERSITEIT LEUVEN BE (LEUVEN) participant 497˙125.00
6    OTTO-VON-GUERICKE-UNIVERSITAET MAGDEBURG DE (MAGDEBURG) participant 495˙000.00
7    UNIVERSITAETSKLINIKUM WUERZBURG - KLINIKUM DER BAYERISCHEN JULIUS-MAXIMILIANS-UNIVERSITAT DE (WURZBURG) participant 449˙500.00
8    ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON EL (ATHINA) participant 414˙250.00
9    INSTITUTE OF COMMUNICATION AND COMPUTER SYSTEMS EL (ATHINA) participant 410˙000.00
10    ZEINCRO EGESZSEGUGYI SZOLGALTATO KORLATOLT FELELOSSEGU TARSASAG HU (BUDAKALASZ) participant 345˙000.00
11    SPHYNX TECHNOLOGY SOLUTIONS AG CH (ZUG) participant 205˙000.00
12    VILABS (CY) LTD CY (LIMASSOL) participant 205˙000.00
13    ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI IT (MILANO) participant 200˙500.00

Map

 Project objective

Tinnitus is the perception of a phantom sound and the patient’s reaction to it. Tinnitus remains a scientific and clinical enigma of iTinnitus is the perception of a phantom sound and the patient’s reaction to it. Although much progress has been made, tinnitus remains a scientific and clinical enigma of high prevalence and high economic burden. It affects more than 10% of the general population, whereas 1% of the population considers tinnitus their major health issue. Recent cohort studies show that tinnitus prevalence tends to increase over time and with older age. Assuming that there is no cure to be found, the prevalence estimates in Europe would double by 2050. A large variety of patient characteristics - including genotyping, aetiology, and phenotyping - are poorly understood, because integrated systems approaches are still missing to correlate patient`s characteristics to predict responses to combinatorial therapies. Although genetic causes of tinnitus have been neglected for decades, recent findings of genetic analysis in specific subgroups (gender and phenotype) have highlighted that bilateral tinnitus in men reached a heritability of 0.68. This heritability is close to autism, schizophrenia and Attention Deficit Hyperactive Disorder (ADHD). There is no current consensus on tinnitus treatment. UNITI’s overall aim is to deliver a predictive computational model based on existing and longitudinal data attempting to address the question which treatment approach is optimal for a specific patient based on specific parameters. Clinical, epidemiological, medical, genetic and audiological data, including signals reflecting ear-brain communication, will be analysed from existing databases. Predictive factors for different patient groups will be extracted and their prognostic relevance will be tested in a randomized controlled trial (RCT) in which different groups of patients will undergo a combination of therapies targeting the auditory and central nervous systems.

 Deliverables

List of deliverables.
Data management plan Open Research Data Pilot 2020-04-07 19:01:53
Creation of the project website Websites, patent fillings, videos etc. 2020-04-07 19:01:46
Dissemination and communication Plan Documents, reports 2020-04-07 18:51:07

Take a look to the deliverables list in detail:  detailed list of UNITI deliverables.

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The information about "UNITI" are provided by the European Opendata Portal: CORDIS opendata.

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