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UNITI SIGNED

Unification of treatments and Interventions for Tinnitus patients

Total Cost €

EC-Contrib. €

Partnership

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UNITI project word cloud

Explore the words cloud of the UNITI project. It provides you a very rough idea of what is the project "UNITI" about.

issue genotyping predictive 68 combinatorial brain whereas epidemiological groups close treatment hyperactive undergo communication burden subgroups itinnitus variety perception cure double missing optimal combination poorly tested decades attempting phantom assuming found disorder causes patient 2050 auditory model signals computational tinnitus estimates older therapies patients reached databases clinical ear reflecting correlate data reaction aetiology 1 audiological men genetic uniti randomized health heritability relevance longitudinal rct population bilateral extracted trial question prognostic progress sound prevalence cohort adhd predict central deficit consensus age made phenotype phenotyping analysed time highlighted medical enigma schizophrenia nervous tends economic autism 10 gender scientific

Project "UNITI" data sheet

The following table provides information about the project.

Coordinator	KLINIKUM DER UNIVERSITAET REGENSBURG Organization address address: FRANS JOSEF STRAUSS ALLEE 11 city: REGENSBURG postcode: 93053 website: www-cgi.uni-regensburg.de/Klinik/Klinikum/ contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Germany [DE]
Total cost	5˙989˙343 €
EC max contribution	5˙989˙343 € (100%)
Programme	1. H2020-EU.3.1.1. (Understanding health, wellbeing and disease)
Code Call	H2020-SC1-2019-Two-Stage-RTD
Funding Scheme	RIA
Starting year	2020
Duration (year-month-day)	from 2020-01-01 to 2023-03-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	KLINIKUM DER UNIVERSITAET REGENSBURG KLINIKUM DER UNIVERSITAET REGENSBURG Organization address address: FRANS JOSEF STRAUSS ALLEE 11 city: REGENSBURG postcode: 93053 website: www-cgi.uni-regensburg.de/Klinik/Klinikum/ contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (REGENSBURG)	coordinator	884˙948.00
2	SERVICIO ANDALUZ DE SALUD SERVICIO ANDALUZ DE SALUD Organization address address: AVENIDA DE LA CONSTITUCION 18 city: SEVILLA postcode: 41071 website: http://www.sas.junta-andalucia.es/principal/default.asp contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (SEVILLA)	participant	696˙875.00
3	KAROLINSKA INSTITUTET KAROLINSKA INSTITUTET Organization address address: Nobels Vag 5 city: STOCKHOLM postcode: 17177 website: www.ki.se contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	SE (STOCKHOLM)	participant	686˙645.00
4	CHARITE - UNIVERSITAETSMEDIZIN BERLIN CHARITE - UNIVERSITAETSMEDIZIN BERLIN Organization address address: Chariteplatz 1 city: BERLIN postcode: 10117 website: www.charite.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (BERLIN)	participant	499˙500.00
5	KATHOLIEKE UNIVERSITEIT LEUVEN KATHOLIEKE UNIVERSITEIT LEUVEN Organization address address: OUDE MARKT 13 city: LEUVEN postcode: 3000 website: www.kuleuven.be contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (LEUVEN)	participant	497˙125.00
6	OTTO-VON-GUERICKE-UNIVERSITAET MAGDEBURG OTTO-VON-GUERICKE-UNIVERSITAET MAGDEBURG Organization address address: UNIVERSITAETSPLATZ 2 city: MAGDEBURG postcode: 39106 website: www.ovgu.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (MAGDEBURG)	participant	495˙000.00
7	UNIVERSITAETSKLINIKUM WUERZBURG - KLINIKUM DER BAYERISCHEN JULIUS-MAXIMILIANS-UNIVERSITAT UNIVERSITAETSKLINIKUM WUERZBURG - KLINIKUM DER BAYERISCHEN JULIUS-MAXIMILIANS-UNIVERSITAT Organization address address: JOSEF-SCHNEIDER-STRASSE 2 city: WURZBURG postcode: 97080 website: www.uk-wuerzburg.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (WURZBURG)	participant	449˙500.00
8	ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON Organization address address: 6 CHRISTOU LADA STR city: ATHINA postcode: 10561 website: www.elke.uoa.gr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	EL (ATHINA)	participant	414˙250.00
9	INSTITUTE OF COMMUNICATION AND COMPUTER SYSTEMS INSTITUTE OF COMMUNICATION AND COMPUTER SYSTEMS Organization address address: Patission Str. 42 city: ATHINA postcode: 10682 website: www.iccs.gr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	EL (ATHINA)	participant	410˙000.00
10	ZEINCRO EGESZSEGUGYI SZOLGALTATO KORLATOLT FELELOSSEGU TARSASAG ZEINCRO EGESZSEGUGYI SZOLGALTATO KORLATOLT FELELOSSEGU TARSASAG Organization address address: JOZSEFF ATTILA UTCA 46. city: BUDAKALASZ postcode: 2011 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	HU (BUDAKALASZ)	participant	345˙000.00
11	SPHYNX TECHNOLOGY SOLUTIONS AG SPHYNX TECHNOLOGY SOLUTIONS AG Organization address address: C/O ASVITO AG CHOLLERSTRASSE 35 city: ZUG postcode: 6300 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CH (ZUG)	participant	205˙000.00
12	VILABS (CY) LTD VILABS (CY) LTD Organization address address: VASILI VRYONIDI 6 GALA COURT CHAMBERS 3RD FLOOR FLAT OFFICE 301 city: LIMASSOL postcode: 3095 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CY (LIMASSOL)	participant	205˙000.00
13	ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI Organization address address: VIA MARIO NEGRI 2 city: MILANO postcode: 20156 website: www.marionegri.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (MILANO)	participant	200˙500.00

Map

Project objective

Tinnitus is the perception of a phantom sound and the patient’s reaction to it. Tinnitus remains a scientific and clinical enigma of iTinnitus is the perception of a phantom sound and the patient’s reaction to it. Although much progress has been made, tinnitus remains a scientific and clinical enigma of high prevalence and high economic burden. It affects more than 10% of the general population, whereas 1% of the population considers tinnitus their major health issue. Recent cohort studies show that tinnitus prevalence tends to increase over time and with older age. Assuming that there is no cure to be found, the prevalence estimates in Europe would double by 2050. A large variety of patient characteristics - including genotyping, aetiology, and phenotyping - are poorly understood, because integrated systems approaches are still missing to correlate patient`s characteristics to predict responses to combinatorial therapies. Although genetic causes of tinnitus have been neglected for decades, recent findings of genetic analysis in specific subgroups (gender and phenotype) have highlighted that bilateral tinnitus in men reached a heritability of 0.68. This heritability is close to autism, schizophrenia and Attention Deficit Hyperactive Disorder (ADHD). There is no current consensus on tinnitus treatment. UNITI’s overall aim is to deliver a predictive computational model based on existing and longitudinal data attempting to address the question which treatment approach is optimal for a specific patient based on specific parameters. Clinical, epidemiological, medical, genetic and audiological data, including signals reflecting ear-brain communication, will be analysed from existing databases. Predictive factors for different patient groups will be extracted and their prognostic relevance will be tested in a randomized controlled trial (RCT) in which different groups of patients will undergo a combination of therapies targeting the auditory and central nervous systems.

Deliverables

List of deliverables.
Data management plan	Open Research Data Pilot	2020-04-07 19:01:53
Creation of the project website	Websites, patent fillings, videos etc.	2020-04-07 19:01:46
Dissemination and communication Plan	Documents, reports	2020-04-07 18:51:07

Take a look to the deliverables list in detail: detailed list of UNITI deliverables.

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The information about "UNITI" are provided by the European Opendata Portal: CORDIS opendata.