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UNITI SIGNED

Unification of treatments and Interventions for Tinnitus patients

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 UNITI project word cloud

Explore the words cloud of the UNITI project. It provides you a very rough idea of what is the project "UNITI" about.

issue    genotyping    predictive    68    combinatorial    brain    whereas    epidemiological    groups    close    treatment    hyperactive    undergo    communication    burden    subgroups    itinnitus    variety    perception    cure    double    missing    optimal    combination    poorly    tested    decades    attempting    phantom    assuming    found    disorder    causes    patient    2050    auditory    model    signals    computational    tinnitus    estimates    older    therapies    patients    reached    databases    clinical    ear    reflecting    correlate    data    reaction    aetiology       audiological    men    genetic    uniti    randomized    health    heritability    relevance    longitudinal    rct    population    bilateral    extracted    trial    question    prognostic    progress    sound    prevalence    cohort    adhd    predict    central    deficit    consensus    age    made    phenotype    phenotyping    analysed    time    highlighted    medical    enigma    schizophrenia    nervous    tends    economic    autism    10    gender    scientific   

Project "UNITI" data sheet

The following table provides information about the project.

Coordinator
KLINIKUM DER UNIVERSITAET REGENSBURG 

Organization address
address: FRANS JOSEF STRAUSS ALLEE 11
city: REGENSBURG
postcode: 93053
website: www-cgi.uni-regensburg.de/Klinik/Klinikum/

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Total cost 5˙989˙343 €
 EC max contribution 5˙989˙343 € (100%)
 Programme 1. H2020-EU.3.1.1. (Understanding health, wellbeing and disease)
 Code Call H2020-SC1-2019-Two-Stage-RTD
 Funding Scheme RIA
 Starting year 2020
 Duration (year-month-day) from 2020-01-01   to  2023-03-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    KLINIKUM DER UNIVERSITAET REGENSBURG DE (REGENSBURG) coordinator 884˙948.00
2    SERVICIO ANDALUZ DE SALUD ES (SEVILLA) participant 696˙875.00
3    KAROLINSKA INSTITUTET SE (STOCKHOLM) participant 686˙645.00
4    CHARITE - UNIVERSITAETSMEDIZIN BERLIN DE (BERLIN) participant 499˙500.00
5    KATHOLIEKE UNIVERSITEIT LEUVEN BE (LEUVEN) participant 497˙125.00
6    OTTO-VON-GUERICKE-UNIVERSITAET MAGDEBURG DE (MAGDEBURG) participant 495˙000.00
7    UNIVERSITAETSKLINIKUM WUERZBURG - KLINIKUM DER BAYERISCHEN JULIUS-MAXIMILIANS-UNIVERSITAT DE (WURZBURG) participant 449˙500.00
8    ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON EL (ATHINA) participant 414˙250.00
9    INSTITUTE OF COMMUNICATION AND COMPUTER SYSTEMS EL (ATHINA) participant 410˙000.00
10    ZEINCRO EGESZSEGUGYI SZOLGALTATO KORLATOLT FELELOSSEGU TARSASAG HU (BUDAKALASZ) participant 345˙000.00
11    SPHYNX TECHNOLOGY SOLUTIONS AG CH (ZUG) participant 205˙000.00
12    VILABS (CY) LTD CY (LIMASSOL) participant 205˙000.00
13    ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI IT (MILANO) participant 200˙500.00

Map

 Project objective

Tinnitus is the perception of a phantom sound and the patient’s reaction to it. Tinnitus remains a scientific and clinical enigma of iTinnitus is the perception of a phantom sound and the patient’s reaction to it. Although much progress has been made, tinnitus remains a scientific and clinical enigma of high prevalence and high economic burden. It affects more than 10% of the general population, whereas 1% of the population considers tinnitus their major health issue. Recent cohort studies show that tinnitus prevalence tends to increase over time and with older age. Assuming that there is no cure to be found, the prevalence estimates in Europe would double by 2050. A large variety of patient characteristics - including genotyping, aetiology, and phenotyping - are poorly understood, because integrated systems approaches are still missing to correlate patient`s characteristics to predict responses to combinatorial therapies. Although genetic causes of tinnitus have been neglected for decades, recent findings of genetic analysis in specific subgroups (gender and phenotype) have highlighted that bilateral tinnitus in men reached a heritability of 0.68. This heritability is close to autism, schizophrenia and Attention Deficit Hyperactive Disorder (ADHD). There is no current consensus on tinnitus treatment. UNITI’s overall aim is to deliver a predictive computational model based on existing and longitudinal data attempting to address the question which treatment approach is optimal for a specific patient based on specific parameters. Clinical, epidemiological, medical, genetic and audiological data, including signals reflecting ear-brain communication, will be analysed from existing databases. Predictive factors for different patient groups will be extracted and their prognostic relevance will be tested in a randomized controlled trial (RCT) in which different groups of patients will undergo a combination of therapies targeting the auditory and central nervous systems.

 Deliverables

List of deliverables.
Data management plan Open Research Data Pilot 2020-04-07 19:01:53
Creation of the project website Websites, patent fillings, videos etc. 2020-04-07 19:01:46
Dissemination and communication Plan Documents, reports 2020-04-07 18:51:07

Take a look to the deliverables list in detail:  detailed list of UNITI deliverables.

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The information about "UNITI" are provided by the European Opendata Portal: CORDIS opendata.

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