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SBR SIGNED

SMART BONE REGENERATION

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 SBR project word cloud

Explore the words cloud of the SBR project. It provides you a very rough idea of what is the project "SBR" about.

of    smart    agents    proof    scaffold    reconstruction    inks    customized    grade    strategies    characterization    suitable    fibers    placement    healthcare    pathology    embed    preclinical    aged    sbr    stem    patient    pressure    particulate    adjustement    proper    3d    electrospun    elaborated    global    tested    inflammation    vital    ph    bone    compatibility    parts    bioactive    defects    printed    temperature    electronic    restoration    introduces    physiology    scope    regulatory    programming    embedding    engineering    explore    monitoring    clinical    efficacy    fast    tissue    enriched    inspired    adjustable    specifications    polymers    medical    animal    treatment    suffer    vivo    population    implant    gender    mechanical    conventional    model    commercialization    infection    chain    ideal    vitro    strategy    immunorejection    srb    innovative    allografts    biocompatible    communication    injury    limited    conductive    identification    autografts    cells    minimal    sensors    solution    performance    regenerative    resorbable   

Project "SBR" data sheet

The following table provides information about the project.

Coordinator
PANEPISTIMIO PATRON 

Organization address
address: UNIVERSITY CAMPUS RIO PATRAS
city: RIO PATRAS
postcode: 265 04
website: www.upatras.gr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Greece [EL]
 Total cost 6˙379˙337 €
 EC max contribution 6˙379˙337 € (100%)
 Programme 1. H2020-EU.3.1.3. (Treating and managing disease)
 Code Call H2020-SC1-2019-Single-Stage-RTD
 Funding Scheme RIA
 Starting year 2020
 Duration (year-month-day) from 2020-01-01   to  2023-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    PANEPISTIMIO PATRON EL (RIO PATRAS) coordinator 779˙318.00
2    CSEM CENTRE SUISSE D'ELECTRONIQUE ET DE MICROTECHNIQUE SA - RECHERCHE ET DEVELOPPEMENT CH (NEUCHATEL) participant 989˙945.00
3    ACONDICIONAMIENTO TARRASENSE ASSOCIACION ES (TERRASSA) participant 854˙335.00
4    GENES'INK FR (ROUSSET) participant 740˙062.00
5    KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN DE (MUENCHEN) participant 643˙125.00
6    RESCOLL FR (PESSAC) participant 581˙193.00
7    EURICE EUROPEAN RESEARCH AND PROJECT OFFICE GMBH DE (ST INGBERT) participant 502˙500.00
8    UNIVERSITY OF LEEDS UK (LEEDS) participant 490˙232.00
9    OZ BIOSCIENCES SAS FR (MARSEILLE) participant 480˙500.00
10    ASPHALION SL ES (BARCELONA) participant 318˙125.00

Map

 Project objective

The management and reconstruction of bone defects is a significant global healthcare challenge. While autografts offer ideal compatibility, they are often not suitable for large bone defects, and allografts suffer from potential immunorejection.The limited efficacy of conventional treatment strategies for large bone defects and the increasing aged population, has inspired the consortium to propose a SMART RESORBABLE BONE (SRB) IMPLANT embedding stem cells and bioactive agents with the aim of a controllable and fast restoration. The proposed solution includes 3D printed medical grade polymers enriched with electrospun fibers (for increased mechanical properties) that can be customized for patient physiology, pathology, and gender. The scaffold design will ensure easy and minimal Injury placement, and will embed different sensors for monitoring e.g. pressure, pH value and temperature based on biocompatible conductive inks. The smart implant will thus be able to provide vital information of implant performance in terms of bone growth and infection/inflammation. The proposed method is unique because it includes a customized smart implant (3D printed parts with adjustable sensors and communication electronic system), together with tissue engineering methods i.e. in-vitro programming of stem cells for embedding into the smart implant. The proposed solution introduces an innovative regenerative chain, from early testing and characterization (identification/adjustement of the proper specifications) and embedding regenerative stem cells and particulate bioactive agents into the smart implant in preclinical research (in-vitro). The in vivo proof of concept of SBR solution will be tested in (large animal model) preclinical studies within the scope of the project. Finally the regulatory and commercialization strategy on how to further explore the proposed concept and deliver it for clinical testing will be elaborated.

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The information about "SBR" are provided by the European Opendata Portal: CORDIS opendata.

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