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SBR SIGNED

SMART BONE REGENERATION

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 SBR project word cloud

Explore the words cloud of the SBR project. It provides you a very rough idea of what is the project "SBR" about.

scaffold    proper    global    sensors    explore    of    compatibility    sbr    treatment    innovative    customized    enriched    clinical    immunorejection    bone    implant    patient    resorbable    strategy    cells    allografts    regenerative    suffer    tested    model    inspired    conventional    conductive    engineering    regulatory    population    healthcare    vital    placement    pressure    tissue    reconstruction    physiology    parts    srb    electronic    performance    introduces    adjustement    stem    preclinical    elaborated    injury    inks    scope    biocompatible    inflammation    infection    fast    embed    proof    smart    vitro    mechanical    aged    defects    strategies    pathology    minimal    embedding    temperature    programming    efficacy    printed    animal    electrospun    3d    gender    solution    polymers    ph    adjustable    fibers    medical    ideal    grade    commercialization    vivo    monitoring    restoration    particulate    specifications    limited    chain    bioactive    autografts    communication    identification    characterization    agents    suitable   

Project "SBR" data sheet

The following table provides information about the project.

Coordinator
PANEPISTIMIO PATRON 

Organization address
address: UNIVERSITY CAMPUS RIO PATRAS
city: RIO PATRAS
postcode: 265 04
website: www.upatras.gr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Greece [EL]
 Total cost 6˙379˙337 €
 EC max contribution 6˙379˙337 € (100%)
 Programme 1. H2020-EU.3.1.3. (Treating and managing disease)
 Code Call H2020-SC1-2019-Single-Stage-RTD
 Funding Scheme RIA
 Starting year 2020
 Duration (year-month-day) from 2020-01-01   to  2023-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    PANEPISTIMIO PATRON EL (RIO PATRAS) coordinator 779˙318.00
2    CSEM CENTRE SUISSE D'ELECTRONIQUE ET DE MICROTECHNIQUE SA - RECHERCHE ET DEVELOPPEMENT CH (NEUCHATEL) participant 989˙945.00
3    ACONDICIONAMIENTO TARRASENSE ASSOCIACION ES (TERRASSA) participant 854˙335.00
4    GENES'INK FR (ROUSSET) participant 740˙062.00
5    KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN DE (MUENCHEN) participant 643˙125.00
6    RESCOLL FR (PESSAC) participant 581˙193.00
7    EURICE EUROPEAN RESEARCH AND PROJECT OFFICE GMBH DE (ST INGBERT) participant 502˙500.00
8    UNIVERSITY OF LEEDS UK (LEEDS) participant 490˙232.00
9    OZ BIOSCIENCES SAS FR (MARSEILLE) participant 480˙500.00
10    ASPHALION SL ES (BARCELONA) participant 318˙125.00

Map

 Project objective

The management and reconstruction of bone defects is a significant global healthcare challenge. While autografts offer ideal compatibility, they are often not suitable for large bone defects, and allografts suffer from potential immunorejection.The limited efficacy of conventional treatment strategies for large bone defects and the increasing aged population, has inspired the consortium to propose a SMART RESORBABLE BONE (SRB) IMPLANT embedding stem cells and bioactive agents with the aim of a controllable and fast restoration. The proposed solution includes 3D printed medical grade polymers enriched with electrospun fibers (for increased mechanical properties) that can be customized for patient physiology, pathology, and gender. The scaffold design will ensure easy and minimal Injury placement, and will embed different sensors for monitoring e.g. pressure, pH value and temperature based on biocompatible conductive inks. The smart implant will thus be able to provide vital information of implant performance in terms of bone growth and infection/inflammation. The proposed method is unique because it includes a customized smart implant (3D printed parts with adjustable sensors and communication electronic system), together with tissue engineering methods i.e. in-vitro programming of stem cells for embedding into the smart implant. The proposed solution introduces an innovative regenerative chain, from early testing and characterization (identification/adjustement of the proper specifications) and embedding regenerative stem cells and particulate bioactive agents into the smart implant in preclinical research (in-vitro). The in vivo proof of concept of SBR solution will be tested in (large animal model) preclinical studies within the scope of the project. Finally the regulatory and commercialization strategy on how to further explore the proposed concept and deliver it for clinical testing will be elaborated.

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The information about "SBR" are provided by the European Opendata Portal: CORDIS opendata.

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