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UNREDE SIGNED

Understanding Non-Photochemical Quenching Regulation in a Dynamic Environment.

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 UNREDE project word cloud

Explore the words cloud of the UNREDE project. It provides you a very rough idea of what is the project "UNREDE" about.

experimental    regulation    trigger    water    components    poorly    stress    pharmacological    dynamic    capability    effect    catalyze    relies    efficiency    deficit    signaling    organism    grow    absorption    evolution    mutant    photo    quenching    behave    carbon    goals    reinhardtii    transcriptomic    generation    levels    temperature    nature    absorbed    apparatus    involve    tolerance    model    maximized    environments    circuits    oxidative    gene    photochemical    regulatory    photosynthetic    capture    converts    properly    chlorophylls    integrity    fixation    molecules    vary    species    harvesting    damage    photosynthesis    unable    earth    atmospheric    alleviate    global    organic    lhcsr    deprivation    life    light    strains    capacity    reactive    oxygen    bound    excess    severe    elicit    seconds    survive    protect    mechanisms    lhc    exceeds    strategies    chlamydomonas    algae    proteins    energy    dioxide    critical    harsh    organisms    npq    elucidate    characterization    nutrient    predict    timescale    expression    explore    environment    minutes    complexes    intensities    suboptimal   

Project "UNREDE" data sheet

The following table provides information about the project.

Coordinator
UNIVERSIDAD DE CORDOBA 

Organization address
address: AVENIDA DE MEDINA AZAHARA 5
city: CORDOBA
postcode: 14005
website: www.uco.es

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Spain [ES]
 Total cost 257˙191 €
 EC max contribution 257˙191 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2016
 Funding Scheme MSCA-IF-GF
 Starting year 2018
 Duration (year-month-day) from 2018-01-15   to  2021-01-14

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSIDAD DE CORDOBA ES (CORDOBA) coordinator 257˙191.00
2    CARNEGIE INSTITUTION OF WASHINGTON US (WASHINGTON DC) partner 0.00

Map

 Project objective

Life on Earth relies on photosynthesis that converts water and carbon dioxide into organic molecules using absorbed light by chlorophylls bound to light harvesting complexes (LHC). During evolution, LHC have maximized the capability to capture light energy, allowing organisms to grow even in very low light environments. However, during nutrient deprivation or under high light conditions, when light absorption exceeds the capacity for carbon dioxide fixation, the excess absorbed energy can elicit the generation of reactive oxygen species that cause severe oxidative damage. Photosynthetic organisms have developed mechanisms of non-photochemical quenching (NPQ) that alleviate this photo-oxidative stress in the timescale of seconds to minutes. This NPQ is critical to protect the integrity of the photosynthetic apparatus, allowing the organisms to survive in a dynamic light and nutrient environment. In algae, LHCSR (LHC Stress Related) proteins catalyze NPQ, but their specific role and regulation are poorly understood. For this project, I will use the model organism Chlamydomonas reinhardtii in which two LHCSR proteins have been identified. My main goals will be (1) to characterize components involved in NPQ under conditions experienced in nature, where light intensities vary and nutrient conditions (C, N and S) are suboptimal, and (2) to explore regulatory circuits and signaling molecules that impact NPQ. The experimental approaches involve characterization of novel mutant strains unable to properly trigger NPQ, transcriptomic analysis to elucidate the effect of NPQ deficit on global gene expression and pharmacological approaches to explore the impact of different signaling molecules in NPQ. Understanding NPQ is essential to predict how photosynthetic organisms will behave with changes in atmospheric dioxide fixation levels, temperature and nutrient availability, but will also impact strategies for improving photosynthetic efficiency and tolerance to harsh conditions.

 Publications

year authors and title journal last update
List of publications.
2019 Arthur Grossman, Emanuel Sanz-Luque, Heng Yi, Wenqiang Yang
Building the GreenCut2 suite of proteins to unmask photosynthetic function and regulation
published pages: 697-718, ISSN: 1350-0872, DOI: 10.1099/mic.0.000788
Microbiology 165/7 2020-04-07
2018 Emanuel Sanz-Luque, Amaury Montaigu
Phenol-based Extraction of RNA from Chlamydomonas reinhardtii
published pages: , ISSN: 2331-8325, DOI: 10.21769/bioprotoc.2910
BIO-PROTOCOL 8/13 2020-04-07

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