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CorticalSpaceShift SIGNED

How altered sensory experience changes the cortex: plasticity processes in the visual cortex and their relation to ecological real-life events under shifted perception condition

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 CorticalSpaceShift project word cloud

Explore the words cloud of the CorticalSpaceShift project. It provides you a very rough idea of what is the project "CorticalSpaceShift" about.

creates    environment    fmri    primary    stimuli    imaging    magnetic    hemispheric    properly    suffering    neglect    cortex    specially    daily    physiological    controls    combining    cortical    space    pattern    explore    cortices    translational    neurologically    probe    hemispatial    virtual    behavioural    lateral    intact    connectivity    conversely    expertise    altered    multisensory    designed    temporary    world    patterns    brain    pa    reflected    tackle    impairment    neuronal    vr    interactions    perceptual    treatment    resonance    mimicking    questions    ecological    visual    prism    acquired    training    events    deficits    ameliorating    stroke    patients    individuals    severity    adapt    left    forge    discoveries    create    platform    function    parietal    life    inability    shift    sensory    dependent    healthy    device    surrounding    multiple    attend    exposure    functional    specialization    combines    imbalanced    rehabilitation    interact    host    triggers    researcher    basis    plasticity    motor    damaged   

Project "CorticalSpaceShift" data sheet

The following table provides information about the project.

Coordinator
CENTRE HOSPITALIER UNIVERSITAIRE VAUDOIS 

Organization address
address: RUE DU BUGNON 21
city: LAUSANNE
postcode: 1011
website: www.chuv.ch

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Switzerland [CH]
 Total cost 187˙419 €
 EC max contribution 187˙419 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-EF-SE
 Starting year 2018
 Duration (year-month-day) from 2018-09-01   to  2020-08-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    CENTRE HOSPITALIER UNIVERSITAIRE VAUDOIS CH (LAUSANNE) coordinator 187˙419.00

Map

 Project objective

To properly function in daily life we need to interact with our surrounding world. How do these interactions forge our sensory cortices? And how does our visual cortex adapt in order to function in an altered environment? The proposed study combines functional magnetic resonance imaging (fMRI) and novel analysis of ecological real-life events with sensory-motor training in order to tackle these questions in both healthy and brain damaged individuals. We will use a specially designed virtual-reality-based prism-adaptation device (VR-PA) that creates a lateral shift in the user’s sensory experience, to probe experience-dependent changes in visual cortex functional connectivity. The VR-PA device will be used for rehabilitation of stroke patients suffering from an inability to attend stimuli in the left side of space (hemispatial neglect). We will explore the neuronal basis of this perceptual rehabilitation using functional connectivity methods in hemispatial neglect patients and in neurologically intact participants. We will use novel fMRI analyses to study how the severity of the perceptual impairment in neglect patients before treatment is reflected in altered pattern of intra-hemispheric connectivity in the primary visual cortex and in its connectivity with parietal areas. We will test whether exposure to VR-PA in healthy controls would result in a temporary imbalanced connectivity pattern, mimicking the patients’ condition. Conversely, in patients, VR-PA training, ameliorating perceptual deficits, would make connectivity patterns more similar to those of an intact brain. Multiple behavioural and physiological measures will be acquired during the training to identify key behavioural triggers of cortical plasticity. Combining the researcher's expertise in functional connectivity and the host specialization in multisensory-motor plasticity would create a platform for novel discoveries in the field of training-induced plasticity and its translational applications.

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The information about "CORTICALSPACESHIFT" are provided by the European Opendata Portal: CORDIS opendata.

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