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CorticalSpaceShift SIGNED

How altered sensory experience changes the cortex: plasticity processes in the visual cortex and their relation to ecological real-life events under shifted perception condition

Total Cost €

0

EC-Contrib. €

0

Partnership

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 CorticalSpaceShift project word cloud

Explore the words cloud of the CorticalSpaceShift project. It provides you a very rough idea of what is the project "CorticalSpaceShift" about.

visual    connectivity    probe    patterns    surrounding    temporary    left    translational    events    platform    pattern    ecological    pa    basis    functional    specially    deficits    dependent    motor    controls    lateral    behavioural    imaging    severity    function    training    multisensory    acquired    sensory    neuronal    stroke    altered    tackle    forge    life    neglect    imbalanced    inability    ameliorating    impairment    parietal    suffering    explore    patients    exposure    triggers    combining    multiple    hemispatial    physiological    healthy    creates    discoveries    daily    brain    virtual    plasticity    researcher    expertise    cortex    environment    questions    specialization    perceptual    prism    treatment    interact    neurologically    shift    damaged    interactions    conversely    fmri    individuals    primary    resonance    world    cortical    intact    cortices    properly    adapt    designed    device    create    reflected    space    magnetic    stimuli    combines    rehabilitation    attend    hemispheric    host    mimicking    vr   

Project "CorticalSpaceShift" data sheet

The following table provides information about the project.

Coordinator
CENTRE HOSPITALIER UNIVERSITAIRE VAUDOIS 

Organization address
address: RUE DU BUGNON 21
city: LAUSANNE
postcode: 1011
website: www.chuv.ch

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Switzerland [CH]
 Total cost 187˙419 €
 EC max contribution 187˙419 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-EF-SE
 Starting year 2018
 Duration (year-month-day) from 2018-09-01   to  2020-08-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    CENTRE HOSPITALIER UNIVERSITAIRE VAUDOIS CH (LAUSANNE) coordinator 187˙419.00

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 Project objective

To properly function in daily life we need to interact with our surrounding world. How do these interactions forge our sensory cortices? And how does our visual cortex adapt in order to function in an altered environment? The proposed study combines functional magnetic resonance imaging (fMRI) and novel analysis of ecological real-life events with sensory-motor training in order to tackle these questions in both healthy and brain damaged individuals. We will use a specially designed virtual-reality-based prism-adaptation device (VR-PA) that creates a lateral shift in the user’s sensory experience, to probe experience-dependent changes in visual cortex functional connectivity. The VR-PA device will be used for rehabilitation of stroke patients suffering from an inability to attend stimuli in the left side of space (hemispatial neglect). We will explore the neuronal basis of this perceptual rehabilitation using functional connectivity methods in hemispatial neglect patients and in neurologically intact participants. We will use novel fMRI analyses to study how the severity of the perceptual impairment in neglect patients before treatment is reflected in altered pattern of intra-hemispheric connectivity in the primary visual cortex and in its connectivity with parietal areas. We will test whether exposure to VR-PA in healthy controls would result in a temporary imbalanced connectivity pattern, mimicking the patients’ condition. Conversely, in patients, VR-PA training, ameliorating perceptual deficits, would make connectivity patterns more similar to those of an intact brain. Multiple behavioural and physiological measures will be acquired during the training to identify key behavioural triggers of cortical plasticity. Combining the researcher's expertise in functional connectivity and the host specialization in multisensory-motor plasticity would create a platform for novel discoveries in the field of training-induced plasticity and its translational applications.

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The information about "CORTICALSPACESHIFT" are provided by the European Opendata Portal: CORDIS opendata.

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