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switchBoard SIGNED

In the eye of the observer: Visual processing at the heart of the retina

Total Cost €

0

EC-Contrib. €

0

Partnership

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 switchBoard project word cloud

Explore the words cloud of the switchBoard project. It provides you a very rough idea of what is the project "switchBoard" about.

training    completing    class    form    broad    terminals    oriented    relay    self    all    layer    world    edge    neuroscience    circuit    retinal    neuronal    cutting    meet    transforms    inner    bipolar    collect    host    signals    labs    train    ease    regular    young    description    optic    partitioning    transfer    spectrum    imaging    vision    neural    board    compose    receives    visual    photoreceptor    first    retina    chips    network    experimental    outer    channels    exposing    synaptic    formed    output    transgenetics    parallel    techniques    input    ganglion    amongst    cells    serves    students    signal    neurons    operations    nerve    group    switch    principles    entire    broadcasted    extracting    passive    composes    reflecting    models    hold    larger    critical    20    elementary    promise    networks    plexiform    owing    artificial    degeneration    structure    represented    types    circuits    cell    resolution    least    axon   

Project "switchBoard" data sheet

The following table provides information about the project.

Coordinator
EBERHARD KARLS UNIVERSITAET TUEBINGEN 

Organization address
address: GESCHWISTER-SCHOLL-PLATZ
city: TUEBINGEN
postcode: 72074
website: www.uni-tuebingen.de

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Project website http://www.etn-switchboard.eu
 Total cost 3˙867˙784 €
 EC max contribution 3˙867˙784 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2015
 Funding Scheme MSCA-ITN-ETN
 Starting year 2015
 Duration (year-month-day) from 2015-11-01   to  2019-10-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    EBERHARD KARLS UNIVERSITAET TUEBINGEN DE (TUEBINGEN) coordinator 498˙432.00
2    THE UNIVERSITY OF SUSSEX UK (BRIGHTON) participant 522˙504.00
3    UNIVERSITAET INNSBRUCK AT (INNSBRUCK) participant 511˙868.00
4    KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW NL (AMSTERDAM) participant 510˙748.00
5    UNIVERSITETET I BERGEN NO (BERGEN) participant 286˙275.00
6    INILABS AG CH (ZURICH) participant 265˙226.00
7    EKB TECHNOLOGIES LTD IL (Bat Yam) participant 260˙300.00
8    CONSIGLIO NAZIONALE DELLE RICERCHE IT (ROMA) participant 258˙061.00
9    TECHNISCHE UNIVERSITAET WIEN AT (WIEN) participant 255˙934.00
10    CARL VON OSSIETZKY UNIVERSITAET OLDENBURG DE (OLDENBURG) participant 249˙216.00
11    MULTI CHANNEL SYSTEMS MCS GMBH DE (REUTLINGEN) participant 249˙216.00
12    European Vision Institute BE (Ixelles) partner 0.00
13    Grasshopper Films GmbH DE (Tübingen) partner 0.00
14    NATURWISSENSCHAFTLICHES UND MEDIZINISCHES INSTITUT AN DER UNIVERSITAET TUEBINGEN DE (REUTLINGEN) partner 0.00
15    Vilvite-The Bergen Science Center NO (Bergen) partner 0.00

Map

 Project objective

All visual information is broadcasted by an intra-retinal pathway formed by a group of neurons called bipolar cells. They collect photoreceptor signals in the outer retina and relay the signals to the inner retinal neurons. This transfer of visual information is far from passive: Each of the at least 10 bipolar cell types transforms the photoreceptor signals in a unique and highly specific way. As a result, the bipolar cell output signals form the first “elementary operations” from which the neural circuits of the inner retina compose a feature-oriented description of the visual world. Reflecting the partitioning of visual information into parallel channels, the retinal layer in which bipolar cell axon terminals meet their synaptic partners, is highly organized: This so-called “inner plexiform layer” effectively serves as the retina’s “switch board”: The input is provided by the different bipolar cell “channels”, while the output is carried by an even larger number of channels, represented by ganglion cells that form the optic nerve. Each of the ~20 ganglion cell types composes its feature-extracting circuits from a specific set of bipolar cell input it receives. Owing to its regular structure and ease of experimental access, the retina is amongst the best understood self-standing neuronal networks in neuroscience. Indeed, recent advances hold the exciting promise that an in-depth understanding of the bipolar cells – an entire class of neurons – and their role in the first critical steps of visual processing is within reach. Our proposal aims to train young researchers in world-leading research labs towards completing this goal. We will accomplish this by exposing the students to a host of cutting-edge techniques and a broad spectrum of research approaches within the training network – from imaging at synaptic resolution, transgenetics and retina degeneration models to the application of retinal circuit principles for signal processing in artificial vision chips.

 Deliverables

List of deliverables.
DLP Training course Other 2020-03-23 18:47:06
Museum exhibit Websites, patent fillings, videos etc. 2020-03-23 18:47:03
Central advertisement of all open positions; recruitment of 15 ESRs Other 2019-07-09 16:53:25
switchBoard flyer Websites, patent fillings, videos etc. 2019-07-09 16:53:25
switchBoard website Websites, patent fillings, videos etc. 2019-07-09 16:53:25
Training course for CMOS MEA applications Other 2019-07-09 16:53:25
Kick-Off Meeting Other 2019-07-09 16:53:25
Silicon retina training course Other 2019-07-09 16:53:25

Take a look to the deliverables list in detail:  detailed list of switchBoard deliverables.

 Publications

year authors and title journal last update
List of publications.
2019 Ben James, Léa Darnet, José Moya-Díaz, Sofie-Helene Seibel, Leon Lagnado
An amplitude code transmits information at a visual synapse
published pages: 1140-1147, ISSN: 1097-6256, DOI: 10.1038/s41593-019-0403-6
Nature Neuroscience 22/7 2020-01-14
2019 Abhijit Sanjeev, Yuval Kapellner, Nadav Shabairou, Eran Gur, Moshe Sinvani, Zeev Zalevsky
Non-Invasive Imaging Through Scattering Medium by Using a Reverse Response Wavefront Shaping Technique
published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-019-48788-9
Scientific Reports 9/1 2019-12-16
2019 Katrin Franke, André Maia Chagas, Zhijian Zhao, Maxime JY Zimmermann, Philipp Bartel, Yongrong Qiu, Klaudia P Szatko, Tom Baden, Thomas Euler
An arbitrary-spectrum spatial visual stimulator for vision research
published pages: , ISSN: 2050-084X, DOI: 10.7554/elife.48779
eLife 8 2019-12-16
2019 Stephan Tetenborg, Shubhash Chandra Yadav, Bianca Brüggen, Georg R. Zoidl, Sheriar G. Hormuzdi, Hannah Monyer, Geeske M. van Woerden, Ulrike Janssen-Bienhold, Karin Dedek
Localization of Retinal Ca2+/Calmodulin-Dependent Kinase II-β (CaMKII-β) at Bipolar Cell Gap Junctions and Cross-Reactivity of a Monoclonal Anti-CaMKII-β Antibody With Connexin36
published pages: , ISSN: 1662-5099, DOI: 10.3389/fnmol.2019.00206
Frontiers in Molecular Neuroscience 12 2019-11-22
2019 Shubhash C. Yadav, Stephan Tetenborg, Karin Dedek
Gap Junctions in A8 Amacrine Cells Are Made of Connexin36 but Are Differently Regulated Than Gap Junctions in AII Amacrine Cells
published pages: , ISSN: 1662-5099, DOI: 10.3389/fnmol.2019.00099
Frontiers in Molecular Neuroscience 12 2019-11-22
2019 Viviana Guadagni, Martina Biagioni, Elena Novelli, Paolo Aretini, Chiara Maria Mazzanti, Enrica Strettoi
Rescuing cones and daylight vision in retinitis pigmentosa mice
published pages: 10177-10192, ISSN: 0892-6638, DOI: 10.1096/fj.201900414r
The FASEB Journal 33/9 2019-11-22
2019 Giovanna Testa, Marco Mainardi, Chiara Morelli, Francesco Olimpico, Laura Pancrazi, Carla Petrella, Cinzia Severini, Rita Florio, Francesca Malerba, Antonia Stefanov, Enrica Strettoi, Rossella Brandi, Ivan Arisi, Paul Heppenstall, Mario Costa, Simona Capsoni, Antonino Cattaneo
The NGF R100W mutation specifically impairs nociception without affecting cognitive performance in a mouse model of Hereditary Sensory and Autonomic Neuropathy type V
published pages: 0688-19, ISSN: 0270-6474, DOI: 10.1523/jneurosci.0688-19.2019
The Journal of Neuroscience 2019-11-22
2019 Beerend H. J. Winkelman, Marcus H. C. Howlett, Maj-Britt Hölzel, Coen Joling, Kathryn H. Fransen, Gobinda Pangeni, Sander Kamermans, Hiraki Sakuta, Masaharu Noda, Huibert J. Simonsz, Maureen A. McCall, Chris I. De Zeeuw, Maarten Kamermans
Nystagmus in patients with congenital stationary night blindness (CSNB) originates from synchronously firing retinal ganglion cells
published pages: e3000174, ISSN: 1545-7885, DOI: 10.1371/journal.pbio.3000174
PLOS Biology 17/9 2019-11-07
2018 Tom Baden, Ben James, Maxime J. Y. Zimmermann, Phillip Bartel, Dorieke Grijseels, Thomas Euler, Leon Lagnado, Miguel Maravall
Spikeling: A low-cost hardware implementation of a spiking neuron for neuroscience teaching and outreach
published pages: e2006760, ISSN: 1545-7885, DOI: 10.1371/journal.pbio.2006760
PLOS Biology 16/10 2019-07-09

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