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DRiveR SIGNED

How does dopamine link QMP with reproductive repression to mediate colony harmony and productivity in the honeybee?

Total Cost €

0

EC-Contrib. €

0

Partnership

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 DRiveR project word cloud

Explore the words cloud of the DRiveR project. It provides you a very rough idea of what is the project "DRiveR" about.

biology    critical    decline    worker    cells    activate    majority    dopamine    lethal    measuring    services    ovary    honeybee    offspring    80    workers    qmp    apis    pollinate    billion    managed    doses    she    strategy    monitoring    neonicotinoid    behavioural    life    colony    populations    skills    molecular    ovaries    plants    22    species    security    exposure    maintenance    expression    bees    mandibular    seq    transplantation    males    experimental    mellifera    acquire    inhibits    hypothesis    gap    innovative    techniques    pollinator    responsible    communicated    reproduction    pheromones    ecology    queen    sub    gene    pheromone    detected    females    crop    signal    food    combine    acts    insects    fundamental    declining    pollination    extensively    biodiversity    reproductive    pesticides    absence    lay    care    antennae    history    signalling    honeybees    combines    altered    harmony    brain    unfertilised    productivity    reproducing    eggs    annually    animal    passed    performance    maximising    fellowship    remarkable    economy    rna    female    understand    link    ultimately    initiated    arguably    forgo    culture   

Project "DRiveR" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITY OF LEEDS 

Organization address
address: WOODHOUSE LANE
city: LEEDS
postcode: LS2 9JT
website: www.leeds.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Total cost 183˙454 €
 EC max contribution 183˙454 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2016
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2018
 Duration (year-month-day) from 2018-03-01   to  2020-02-29

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITY OF LEEDS UK (LEEDS) coordinator 183˙454.00

Map

 Project objective

Insects pollinate 80% of crop plants in Europe and pollination services contribute €22 billion to the European economy annually. The honeybee (Apis mellifera) is the most extensively managed pollinator species, yet populations are declining. Understanding the biology of the honeybee and and factors contributing to its decline is critical for food security and maintenance of biodiversity. The honeybee has evolved a remarkable life history strategy where only one female is responsible for the majority of reproduction. The other females, the workers, forgo reproducing to care for the queen and her offspring. The presence of a reproductive queen is communicated via pheromones, arguably the most important of which is Queen Mandibular Pheromone (QMP). This pheromone inhibits ovary activity in worker bees and in its absence worker bees can activate their ovaries and lay unfertilised eggs that will become males. QMP is detected by the antennae and brain, but it is not currently known how the signal, initiated by QMP, is passed to the ovary. In this fellowship the applicant will address this fundamental gap in our knowledge by testing her hypothesis that dopamine acts to link the brain and ovary with exposure to QMP in the honeybee. The applicant will determine the role of dopamine signalling in maximising colony productivity and harmony and whether this is altered by sub-lethal doses of neonicotinoid pesticides. The experimental approach proposed in this fellowship is highly innovative as it combines state-of-the-art techniques both for measuring gene expression (RNA-seq) and for ovary culture and transplantation in honeybees. The applicant will combine these molecular approaches with behavioural ecology and colony monitoring (new skills that she will acquire under this fellowship) to understand not just how cells within the honeybee ovary respond to QMP, but how this signal affects the whole animal, its behaviour and, ultimately, the performance of the colony.

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The information about "DRIVER" are provided by the European Opendata Portal: CORDIS opendata.

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