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DRiveR SIGNED

How does dopamine link QMP with reproductive repression to mediate colony harmony and productivity in the honeybee?

Total Cost €

0

EC-Contrib. €

0

Partnership

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 DRiveR project word cloud

Explore the words cloud of the DRiveR project. It provides you a very rough idea of what is the project "DRiveR" about.

ecology    link    services    pesticides    culture    animal    insects    bees    female    doses    experimental    eggs    billion    understand    decline    life    behavioural    combine    maximising    honeybee    critical    22    hypothesis    colony    reproducing    innovative    security    species    techniques    apis    offspring    expression    managed    transplantation    males    measuring    she    initiated    cells    arguably    pollinator    reproduction    harmony    forgo    pollinate    acts    absence    declining    performance    rna    plants    queen    unfertilised    females    economy    exposure    molecular    strategy    maintenance    qmp    extensively    populations    pollination    reproductive    biodiversity    detected    productivity    care    remarkable    ovaries    inhibits    gene    dopamine    food    mellifera    history    crop    altered    signalling    combines    fellowship    seq    lay    worker    pheromones    monitoring    antennae    passed    skills    responsible    ovary    lethal    neonicotinoid    annually    acquire    pheromone    gap    majority    activate    signal    sub    mandibular    brain    honeybees    80    communicated    fundamental    workers    ultimately    biology   

Project "DRiveR" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITY OF LEEDS 

Organization address
address: WOODHOUSE LANE
city: LEEDS
postcode: LS2 9JT
website: www.leeds.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Total cost 183˙454 €
 EC max contribution 183˙454 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2016
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2018
 Duration (year-month-day) from 2018-03-01   to  2020-02-29

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITY OF LEEDS UK (LEEDS) coordinator 183˙454.00

Map

 Project objective

Insects pollinate 80% of crop plants in Europe and pollination services contribute €22 billion to the European economy annually. The honeybee (Apis mellifera) is the most extensively managed pollinator species, yet populations are declining. Understanding the biology of the honeybee and and factors contributing to its decline is critical for food security and maintenance of biodiversity. The honeybee has evolved a remarkable life history strategy where only one female is responsible for the majority of reproduction. The other females, the workers, forgo reproducing to care for the queen and her offspring. The presence of a reproductive queen is communicated via pheromones, arguably the most important of which is Queen Mandibular Pheromone (QMP). This pheromone inhibits ovary activity in worker bees and in its absence worker bees can activate their ovaries and lay unfertilised eggs that will become males. QMP is detected by the antennae and brain, but it is not currently known how the signal, initiated by QMP, is passed to the ovary. In this fellowship the applicant will address this fundamental gap in our knowledge by testing her hypothesis that dopamine acts to link the brain and ovary with exposure to QMP in the honeybee. The applicant will determine the role of dopamine signalling in maximising colony productivity and harmony and whether this is altered by sub-lethal doses of neonicotinoid pesticides. The experimental approach proposed in this fellowship is highly innovative as it combines state-of-the-art techniques both for measuring gene expression (RNA-seq) and for ovary culture and transplantation in honeybees. The applicant will combine these molecular approaches with behavioural ecology and colony monitoring (new skills that she will acquire under this fellowship) to understand not just how cells within the honeybee ovary respond to QMP, but how this signal affects the whole animal, its behaviour and, ultimately, the performance of the colony.

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The information about "DRIVER" are provided by the European Opendata Portal: CORDIS opendata.

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