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DRiveR SIGNED

How does dopamine link QMP with reproductive repression to mediate colony harmony and productivity in the honeybee?

Total Cost €

0

EC-Contrib. €

0

Partnership

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 DRiveR project word cloud

Explore the words cloud of the DRiveR project. It provides you a very rough idea of what is the project "DRiveR" about.

monitoring    molecular    techniques    dopamine    history    expression    life    performance    mandibular    ultimately    critical    worker    hypothesis    detected    combines    exposure    activate    maximising    billion    animal    harmony    economy    pheromones    majority    mellifera    qmp    colony    link    declining    crop    sub    lay    gap    workers    biodiversity    pollination    ovary    neonicotinoid    services    bees    pollinate    skills    doses    behavioural    responsible    insects    species    initiated    passed    combine    reproducing    food    understand    honeybees    remarkable    populations    ovaries    arguably    experimental    reproduction    honeybee    antennae    acts    biology    unfertilised    security    strategy    innovative    measuring    extensively    annually    gene    plants    productivity    female    pesticides    males    managed    transplantation    altered    inhibits    lethal    signalling    pheromone    females    signal    forgo    she    care    rna    acquire    eggs    seq    communicated    queen    cells    culture    maintenance    decline    reproductive    80    fellowship    pollinator    offspring    fundamental    absence    brain    apis    22    ecology   

Project "DRiveR" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITY OF LEEDS 

Organization address
address: WOODHOUSE LANE
city: LEEDS
postcode: LS2 9JT
website: www.leeds.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Total cost 183˙454 €
 EC max contribution 183˙454 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2016
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2018
 Duration (year-month-day) from 2018-03-01   to  2020-02-29

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITY OF LEEDS UK (LEEDS) coordinator 183˙454.00

Map

 Project objective

Insects pollinate 80% of crop plants in Europe and pollination services contribute €22 billion to the European economy annually. The honeybee (Apis mellifera) is the most extensively managed pollinator species, yet populations are declining. Understanding the biology of the honeybee and and factors contributing to its decline is critical for food security and maintenance of biodiversity. The honeybee has evolved a remarkable life history strategy where only one female is responsible for the majority of reproduction. The other females, the workers, forgo reproducing to care for the queen and her offspring. The presence of a reproductive queen is communicated via pheromones, arguably the most important of which is Queen Mandibular Pheromone (QMP). This pheromone inhibits ovary activity in worker bees and in its absence worker bees can activate their ovaries and lay unfertilised eggs that will become males. QMP is detected by the antennae and brain, but it is not currently known how the signal, initiated by QMP, is passed to the ovary. In this fellowship the applicant will address this fundamental gap in our knowledge by testing her hypothesis that dopamine acts to link the brain and ovary with exposure to QMP in the honeybee. The applicant will determine the role of dopamine signalling in maximising colony productivity and harmony and whether this is altered by sub-lethal doses of neonicotinoid pesticides. The experimental approach proposed in this fellowship is highly innovative as it combines state-of-the-art techniques both for measuring gene expression (RNA-seq) and for ovary culture and transplantation in honeybees. The applicant will combine these molecular approaches with behavioural ecology and colony monitoring (new skills that she will acquire under this fellowship) to understand not just how cells within the honeybee ovary respond to QMP, but how this signal affects the whole animal, its behaviour and, ultimately, the performance of the colony.

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The information about "DRIVER" are provided by the European Opendata Portal: CORDIS opendata.

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