Opendata, web and dolomites

LASER OPTIMAL SIGNED

Laser Ablation: SElectivity and monitoRing for OPTImal tuMor removAL

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 LASER OPTIMAL project word cloud

Explore the words cloud of the LASER OPTIMAL project. It provides you a very rough idea of what is the project "LASER OPTIMAL" about.

breaking    image    assessing    closed    extendable    surgical    la    lack    time    fast    accurate    re    therapy    clinicians    clinical    transfer    insights    drive    tumor    practical    ablation    thermal    extensively    selective    extracted    prove    biocompatible    surrounding    pros    alternative    artifact    small    benefits    optimal    embeddable    safe    settings    invasive    guidance    thermally    mini    visualize    ex    light    excellent    investigates    develops    workflow    pancreatic    ground    removal    engineers    healthcare    heat    cancer    renaissance    solutions    simulate    driving    resection    absorption    tests    encourage    events    predict    human    loop    envisaged    performances    merge    model    bnps    tissue    patient    paradigm    destroys    minimally    echo    strategy    nanoparticles    dynamics    interaction    injected    optics    routine    laser    animal    anatomy    vivo    tune    spearing    unpredictable    endoscope    offers    market    trials    fiber    temperature    ambition    physiological    tools    images    innovative    monitor    restrained    mass    treatment    retrieve    tumors    despite    society    industrial    normal   

Project "LASER OPTIMAL" data sheet

The following table provides information about the project.

Coordinator
POLITECNICO DI MILANO 

Organization address
address: PIAZZA LEONARDO DA VINCI 32
city: MILANO
postcode: 20133
website: www.polimi.it

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Italy [IT]
 Total cost 1˙499˙575 €
 EC max contribution 1˙499˙575 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2017-STG
 Funding Scheme ERC-STG
 Starting year 2018
 Duration (year-month-day) from 2018-05-01   to  2023-04-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    POLITECNICO DI MILANO IT (MILANO) coordinator 1˙154˙660.00
2    FONDATION DE COOPERATION SCIENTIFIQUE FR (STRASBOURG) participant 184˙290.00
3    BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE US (DUARTE CA) participant 160˙625.00

Map

 Project objective

Laser Ablation (LA) was extensively investigated for its benefits as minimally invasive thermal therapy for tumor. Despite the LA pros as potential alternative to surgical resection (e.g., use of small fiber optics, echo-endoscope procedures and image-guidance without artifact), the lack of tools for safe and patient-specific treatment restrained its clinical use. LASER OPTIMAL offers a renaissance to LA for the practical management of challenging tumors (e.g., pancreatic cancer): it investigates and develops integrated solutions to achieve an effective and selective LA, that thermally destroys the whole tumor mass, while spearing the normal tissue around. The excellent ambition of LASER OPTIMAL is to achieve and merge: a) biocompatible nanoparticles (BNPs) injected in the tumor, to enhance the selective absorption of laser light; b) patient-specific anatomy of tumor and its surrounding, extracted from clinical images, to retrieve the optimal laser settings; c) accurate, fast and real-time heat-transfer model to simulate laser-tissue-BNPs interaction, predict and visualize the treatment dynamics; d) real-time temperature measurement system to monitor LA effects, account for unpredictable physiological events and tune the settings (closed-loop). The design of ex vivo and in vivo animal tests allows assessing the system performances and driving the possible workflow re-design. Finally, human trials are envisaged to prove the significant impact of the LASER OPTIMAL paradigm. The collaboration of researchers, engineers and clinicians will drive the use of this innovative strategy in clinical routine. The research on the patient-specific system for the mini-invasive tumors removal, and the ground-breaking insights on clinical use of BNPs will strongly impact on EU healthcare system and society, by creating a novel product. This paradigm is also embeddable in existing system of industrial partner, extendable to other procedures, thus able to encourage a dedicated market.

 Publications

year authors and title journal last update
List of publications.
2018 Paola Saccomandi, Alfonso Lapergola, Fabio Longo, Emiliano Schena, Giuseppe Quero
Thermal ablation of pancreatic cancer: A systematic literature review of clinical practice and pre-clinical studies
published pages: 398-418, ISSN: 0265-6736, DOI: 10.1080/02656736.2018.1506165
International Journal of Hyperthermia 35/1 2020-04-24

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "LASER OPTIMAL" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "LASER OPTIMAL" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.1.)

NanoPD_P (2020)

High throughput multiplexed trace-analyte screening for diagnostics applications

Read More  

NeuroMag (2019)

The Neurological Basis of the Magnetic Sense

Read More  

Malaria POC (2019)

Ultrasensitive detection of transmissible malaria

Read More