Opendata, web and dolomites

MgSafe SIGNED

Promoting patient safety by a novel combination of imaging technologies for biodegradable magnesium implants

Total Cost €

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EC-Contrib. €

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Partnership

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 MgSafe project word cloud

Explore the words cloud of the MgSafe project. It provides you a very rough idea of what is the project "MgSafe" about.

explants    label    rats    nano    learning    quantify    merged    safety    point    trained    behavior    simulations    therapy    push    situ    alloys    cesses    area    rules    individual    physical    time    resolution    mainstay    implants    length    computational    uspa    implant    sis    certified    training    15    personal    details    body    class    machine    optimized    diag    severe    valuable    performed    monitoring    biological    sophisticated    techniques    device    upscaling    obtain    degradation    ir    biomedical    invasively    animals    3d    combined    tained    astm    chemical    material    science    leadership    transferable    career    mg    humans    added    positions    mgsafe    nosis    precision    ex    thereby    forefront    ce    vivo    esrs    technologies    dummy    multimodal    mrt    highest    ronment    relevance    clinical    analy    technological    biochemical    imag    tremendous    additional    suitability    sheep    molecular    pet    tion    envi    patient    scales    gradable    plethora    gained    micro    pro    variety    ling    ple    biode    parallel    imaging    combination    ing    modalities    experts    prepared    ob    medical    promises    dimension    skills    ct    options    data    reac    physiological    lack   

Project "MgSafe" data sheet

The following table provides information about the project.

Coordinator
HELMHOLTZ-ZENTRUM GEESTHACHT ZENTRUM FUR MATERIAL- UND KUSTENFORSCHUNG GMBH 

Organization address
address: MAX PLANCK STRASSE 1
city: GEESTHACHT
postcode: 21502
website: www.gkss.de

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Total cost 3˙956˙398 €
 EC max contribution 3˙956˙398 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2018
 Funding Scheme MSCA-ITN-ETN
 Starting year 2018
 Duration (year-month-day) from 2018-10-01   to  2022-09-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    HELMHOLTZ-ZENTRUM GEESTHACHT ZENTRUM FUR MATERIAL- UND KUSTENFORSCHUNG GMBH DE (GEESTHACHT) coordinator 505˙576.00
2    MEDIZINISCHE UNIVERSITAT GRAZ AT (GRAZ) participant 528˙414.00
3    CONSIGLIO NAZIONALE DELLE RICERCHE IT (ROMA) participant 522˙999.00
4    OSLOMET - STORBYUNIVERSITETET NO (OSLO) participant 292˙342.00
5    UNIVERSITETET I OSLO NO (OSLO) participant 292˙342.00
6    GOETEBORGS UNIVERSITET SE (GOETEBORG) participant 281˙982.00
7    SCANCO MEDICAL AG CH (BRUETTISELLEN) participant 281˙276.00
8    FUJIFILM SONOSITE BV NL (AMSTERDAM) participant 265˙619.00
9    MEDIZINISCHE HOCHSCHULE HANNOVER DE (HANNOVER) participant 252˙788.00
10    MRI. TOOLS GMBH DE (BERLIN) participant 252˙788.00
11    SYNTELLIX AG DE (HANNOVER) participant 252˙788.00
12    POLITECHNIKA WARSZAWSKA PL (WARSZAWA) participant 227˙478.00
13    BRI.TECH GMBH AT (GRAZ) partner 0.00

Map

 Project objective

Biomedical imaging has gained a significant technological push and is the mainstay for diag-nosis and therapy monitoring. Still, imaging is yet not optimized for the new class of biode-gradable Mg-based implants. MgSafe addresses this point by training 15 ESRs in both, imag-ing and implant technologies. All ESRs will develop their individual Personal Learning Envi-ronment (PLE) and be trained based on the “T-skills concept” in technologies and transferable skills relevant for their career development and prepared to take over leadership positions in an area of tremendous research promises and clinical relevance where the lack for experts is severe and very well recognized. The ESRs will quantify the physical impact and suitability of a variety of modalities on Mg implants. Highly sophisticated imaging techniques (nano and µCT, MRT, PET, USPA, IR) will be developed beyond the forefront of medical device production in vivo and with in situ label-ling options to deliver non-invasively data on different time and length scales of the body reac-tion and material behavior during Mg degradation with a precision and plethora of details which is currently not available. Two Mg-alloys and CE-certified Mg-implants will be studied in rats and sheep. Dummy studies will be performed in parallel (following ASTM rules). The ob-tained multimodal imaging data will be combined with molecular biological/biochemical analy-sis, thereby increasing the information about physiological changes without using additional animals. An additional dimension will be added by the analysis of explants to obtain highest resolution chemical and material science data. All relevant biological and chemical in vivo and ex vivo data will be merged by computational 3D methods, simulations and machine learning approaches. The combination of these results will not only allow for an upscaling of the pro-cesses towards humans but will also deliver valuable data in terms of patient safety.

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The information about "MGSAFE" are provided by the European Opendata Portal: CORDIS opendata.

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