Opendata, web and dolomites

MgSafe SIGNED

Promoting patient safety by a novel combination of imaging technologies for biodegradable magnesium implants

Total Cost €

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EC-Contrib. €

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Partnership

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 MgSafe project word cloud

Explore the words cloud of the MgSafe project. It provides you a very rough idea of what is the project "MgSafe" about.

molecular    certified    ple    performed    optimized    analy    science    biode    multimodal    esrs    valuable    precision    suitability    therapy    3d    diag    uspa    experts    animals    mg    modalities    15    imaging    envi    ir    safety    physical    physiological    upscaling    cesses    severe    chemical    label    techniques    individual    forefront    vivo    combined    skills    tremendous    explants    learning    biological    variety    time    length    body    ce    nano    class    patient    pro    area    technological    career    pet    lack    quantify    data    computational    thereby    degradation    obtain    machine    nosis    ob    scales    options    sheep    biomedical    medical    biochemical    situ    mrt    transferable    plethora    point    humans    additional    promises    prepared    clinical    material    rats    ronment    monitoring    mgsafe    tion    training    gradable    implant    resolution    gained    reac    tained    micro    dummy    imag    highest    technologies    leadership    positions    mainstay    implants    sophisticated    alloys    merged    rules    personal    parallel    relevance    astm    combination    added    trained    ex    simulations    behavior    dimension    device    invasively    push    ling    details    ct    ing    sis   

Project "MgSafe" data sheet

The following table provides information about the project.

Coordinator
HELMHOLTZ-ZENTRUM GEESTHACHT ZENTRUM FUR MATERIAL- UND KUSTENFORSCHUNG GMBH 

Organization address
address: MAX PLANCK STRASSE 1
city: GEESTHACHT
postcode: 21502
website: www.gkss.de

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Total cost 3˙956˙398 €
 EC max contribution 3˙956˙398 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2018
 Funding Scheme MSCA-ITN-ETN
 Starting year 2018
 Duration (year-month-day) from 2018-10-01   to  2022-09-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    HELMHOLTZ-ZENTRUM GEESTHACHT ZENTRUM FUR MATERIAL- UND KUSTENFORSCHUNG GMBH DE (GEESTHACHT) coordinator 505˙576.00
2    MEDIZINISCHE UNIVERSITAT GRAZ AT (GRAZ) participant 528˙414.00
3    CONSIGLIO NAZIONALE DELLE RICERCHE IT (ROMA) participant 522˙999.00
4    OSLOMET - STORBYUNIVERSITETET NO (OSLO) participant 292˙342.00
5    UNIVERSITETET I OSLO NO (OSLO) participant 292˙342.00
6    GOETEBORGS UNIVERSITET SE (GOETEBORG) participant 281˙982.00
7    SCANCO MEDICAL AG CH (BRUETTISELLEN) participant 281˙276.00
8    FUJIFILM SONOSITE BV NL (AMSTERDAM) participant 265˙619.00
9    MEDIZINISCHE HOCHSCHULE HANNOVER DE (HANNOVER) participant 252˙788.00
10    MRI. TOOLS GMBH DE (BERLIN) participant 252˙788.00
11    SYNTELLIX AG DE (HANNOVER) participant 252˙788.00
12    POLITECHNIKA WARSZAWSKA PL (WARSZAWA) participant 227˙478.00
13    BRI.TECH GMBH AT (GRAZ) partner 0.00

Map

 Project objective

Biomedical imaging has gained a significant technological push and is the mainstay for diag-nosis and therapy monitoring. Still, imaging is yet not optimized for the new class of biode-gradable Mg-based implants. MgSafe addresses this point by training 15 ESRs in both, imag-ing and implant technologies. All ESRs will develop their individual Personal Learning Envi-ronment (PLE) and be trained based on the “T-skills concept” in technologies and transferable skills relevant for their career development and prepared to take over leadership positions in an area of tremendous research promises and clinical relevance where the lack for experts is severe and very well recognized. The ESRs will quantify the physical impact and suitability of a variety of modalities on Mg implants. Highly sophisticated imaging techniques (nano and µCT, MRT, PET, USPA, IR) will be developed beyond the forefront of medical device production in vivo and with in situ label-ling options to deliver non-invasively data on different time and length scales of the body reac-tion and material behavior during Mg degradation with a precision and plethora of details which is currently not available. Two Mg-alloys and CE-certified Mg-implants will be studied in rats and sheep. Dummy studies will be performed in parallel (following ASTM rules). The ob-tained multimodal imaging data will be combined with molecular biological/biochemical analy-sis, thereby increasing the information about physiological changes without using additional animals. An additional dimension will be added by the analysis of explants to obtain highest resolution chemical and material science data. All relevant biological and chemical in vivo and ex vivo data will be merged by computational 3D methods, simulations and machine learning approaches. The combination of these results will not only allow for an upscaling of the pro-cesses towards humans but will also deliver valuable data in terms of patient safety.

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The information about "MGSAFE" are provided by the European Opendata Portal: CORDIS opendata.

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