Opendata, web and dolomites

MgSafe SIGNED

Promoting patient safety by a novel combination of imaging technologies for biodegradable magnesium implants

Total Cost €

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EC-Contrib. €

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Partnership

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 MgSafe project word cloud

Explore the words cloud of the MgSafe project. It provides you a very rough idea of what is the project "MgSafe" about.

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Project "MgSafe" data sheet

The following table provides information about the project.

Coordinator
HELMHOLTZ-ZENTRUM GEESTHACHT ZENTRUM FUR MATERIAL- UND KUSTENFORSCHUNG GMBH 

Organization address
address: MAX PLANCK STRASSE 1
city: GEESTHACHT
postcode: 21502
website: www.gkss.de

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Total cost 3˙956˙398 €
 EC max contribution 3˙956˙398 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2018
 Funding Scheme MSCA-ITN-ETN
 Starting year 2018
 Duration (year-month-day) from 2018-10-01   to  2022-09-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    HELMHOLTZ-ZENTRUM GEESTHACHT ZENTRUM FUR MATERIAL- UND KUSTENFORSCHUNG GMBH DE (GEESTHACHT) coordinator 505˙576.00
2    MEDIZINISCHE UNIVERSITAT GRAZ AT (GRAZ) participant 528˙414.00
3    CONSIGLIO NAZIONALE DELLE RICERCHE IT (ROMA) participant 522˙999.00
4    OSLOMET - STORBYUNIVERSITETET NO (OSLO) participant 292˙342.00
5    UNIVERSITETET I OSLO NO (OSLO) participant 292˙342.00
6    GOETEBORGS UNIVERSITET SE (GOETEBORG) participant 281˙982.00
7    SCANCO MEDICAL AG CH (BRUETTISELLEN) participant 281˙276.00
8    FUJIFILM SONOSITE BV NL (AMSTERDAM) participant 265˙619.00
9    MEDIZINISCHE HOCHSCHULE HANNOVER DE (HANNOVER) participant 252˙788.00
10    MRI. TOOLS GMBH DE (BERLIN) participant 252˙788.00
11    SYNTELLIX AG DE (HANNOVER) participant 252˙788.00
12    POLITECHNIKA WARSZAWSKA PL (WARSZAWA) participant 227˙478.00
13    BRI.TECH GMBH AT (GRAZ) partner 0.00

Map

 Project objective

Biomedical imaging has gained a significant technological push and is the mainstay for diag-nosis and therapy monitoring. Still, imaging is yet not optimized for the new class of biode-gradable Mg-based implants. MgSafe addresses this point by training 15 ESRs in both, imag-ing and implant technologies. All ESRs will develop their individual Personal Learning Envi-ronment (PLE) and be trained based on the “T-skills concept” in technologies and transferable skills relevant for their career development and prepared to take over leadership positions in an area of tremendous research promises and clinical relevance where the lack for experts is severe and very well recognized. The ESRs will quantify the physical impact and suitability of a variety of modalities on Mg implants. Highly sophisticated imaging techniques (nano and µCT, MRT, PET, USPA, IR) will be developed beyond the forefront of medical device production in vivo and with in situ label-ling options to deliver non-invasively data on different time and length scales of the body reac-tion and material behavior during Mg degradation with a precision and plethora of details which is currently not available. Two Mg-alloys and CE-certified Mg-implants will be studied in rats and sheep. Dummy studies will be performed in parallel (following ASTM rules). The ob-tained multimodal imaging data will be combined with molecular biological/biochemical analy-sis, thereby increasing the information about physiological changes without using additional animals. An additional dimension will be added by the analysis of explants to obtain highest resolution chemical and material science data. All relevant biological and chemical in vivo and ex vivo data will be merged by computational 3D methods, simulations and machine learning approaches. The combination of these results will not only allow for an upscaling of the pro-cesses towards humans but will also deliver valuable data in terms of patient safety.

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The information about "MGSAFE" are provided by the European Opendata Portal: CORDIS opendata.

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