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MgSafe SIGNED

Promoting patient safety by a novel combination of imaging technologies for biodegradable magnesium implants

Total Cost €

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EC-Contrib. €

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Partnership

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MgSafe project word cloud

Explore the words cloud of the MgSafe project. It provides you a very rough idea of what is the project "MgSafe" about.

plethora options skills safety dimension body relevance imag performed science physiological mainstay mg ob alloys ex tained invasively material uspa biological positions diag prepared obtain 15 techniques class tion ir modalities envi optimized point data pet transferable biomedical ling 3d added sheep ronment mgsafe rats vivo certified imaging suitability situ combined medical patient ing quantify additional nano severe animals scales length rules parallel esrs mrt analy sis personal simulations therapy highest area implant experts merged ce astm precision learning career tremendous implants ple pro leadership biochemical training ct physical push trained resolution molecular machine micro promises time degradation forefront explants technological technologies details gradable variety thereby chemical gained combination label nosis biode computational reac behavior upscaling monitoring multimodal humans sophisticated clinical valuable dummy individual lack device cesses

Project "MgSafe" data sheet

The following table provides information about the project.

Coordinator	HELMHOLTZ-ZENTRUM GEESTHACHT ZENTRUM FUR MATERIAL- UND KUSTENFORSCHUNG GMBH Organization address address: MAX PLANCK STRASSE 1 city: GEESTHACHT postcode: 21502 website: www.gkss.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Germany [DE]
Total cost	3˙956˙398 €
EC max contribution	3˙956˙398 € (100%)
Programme	1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
Code Call	H2020-MSCA-ITN-2018
Funding Scheme	MSCA-ITN-ETN
Starting year	2018
Duration (year-month-day)	from 2018-10-01 to 2022-09-30

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	HELMHOLTZ-ZENTRUM GEESTHACHT ZENTRUM FUR MATERIAL- UND KUSTENFORSCHUNG GMBH HELMHOLTZ-ZENTRUM GEESTHACHT ZENTRUM FUR MATERIAL- UND KUSTENFORSCHUNG GMBH Organization address address: MAX PLANCK STRASSE 1 city: GEESTHACHT postcode: 21502 website: www.gkss.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (GEESTHACHT)	coordinator	505˙576.00
2	MEDIZINISCHE UNIVERSITAT GRAZ MEDIZINISCHE UNIVERSITAT GRAZ Organization address address: AUENBRUGGERPLATZ 2 city: GRAZ postcode: 8036 website: http://www.medunigraz.at contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	AT (GRAZ)	participant	528˙414.00
3	CONSIGLIO NAZIONALE DELLE RICERCHE CONSIGLIO NAZIONALE DELLE RICERCHE Organization address address: PIAZZALE ALDO MORO 7 city: ROMA postcode: 185 website: www.cnr.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (ROMA)	participant	522˙999.00
4	OSLOMET - STORBYUNIVERSITETET OSLOMET - STORBYUNIVERSITETET Organization address address: PILESTREDET 46 city: OSLO postcode: 167 website: www.hioa.no contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NO (OSLO)	participant	292˙342.00
5	UNIVERSITETET I OSLO UNIVERSITETET I OSLO Organization address address: PROBLEMVEIEN 5-7 city: OSLO postcode: 313 website: www.uio.no contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NO (OSLO)	participant	292˙342.00
6	GOETEBORGS UNIVERSITET GOETEBORGS UNIVERSITET Organization address address: VASAPARKEN city: GOETEBORG postcode: 405 30 website: www.gu.se contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	SE (GOETEBORG)	participant	281˙982.00
7	SCANCO MEDICAL AG SCANCO MEDICAL AG Organization address address: FABRIKWEG 2 city: BRUETTISELLEN postcode: 8306 website: www.scanco.ch contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CH (BRUETTISELLEN)	participant	281˙276.00
8	FUJIFILM SONOSITE BV FUJIFILM SONOSITE BV Organization address address: JOOP GEESINKWEG 140 city: AMSTERDAM postcode: 1114 AB website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (AMSTERDAM)	participant	265˙619.00
9	MEDIZINISCHE HOCHSCHULE HANNOVER MEDIZINISCHE HOCHSCHULE HANNOVER Organization address address: Carl-Neuberg-Strasse 1 city: HANNOVER postcode: 30625 website: www.mh-hannover.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (HANNOVER)	participant	252˙788.00
10	MRI. TOOLS GMBH MRI. TOOLS GMBH Organization address address: ROBERT ROSSLE STRASSE 10 city: BERLIN postcode: 13125 website: www.mritools.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (BERLIN)	participant	252˙788.00
11	SYNTELLIX AG SYNTELLIX AG Organization address address: AEGIDIENTORPLATZ 2A city: HANNOVER postcode: 30159 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (HANNOVER)	participant	252˙788.00
12	POLITECHNIKA WARSZAWSKA POLITECHNIKA WARSZAWSKA Organization address address: PLAC POLITECHNIKI 1 city: WARSZAWA postcode: 00 661 website: http://www.pw.edu.pl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	PL (WARSZAWA)	participant	227˙478.00
13	BRI.TECH GMBH BRI.TECH GMBH Organization address address: ROSSMANNGASSE 21/4 city: GRAZ postcode: 8010 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	AT (GRAZ)	partner	0.00

Map

Project objective

Biomedical imaging has gained a significant technological push and is the mainstay for diag-nosis and therapy monitoring. Still, imaging is yet not optimized for the new class of biode-gradable Mg-based implants. MgSafe addresses this point by training 15 ESRs in both, imag-ing and implant technologies. All ESRs will develop their individual Personal Learning Envi-ronment (PLE) and be trained based on the “T-skills concept” in technologies and transferable skills relevant for their career development and prepared to take over leadership positions in an area of tremendous research promises and clinical relevance where the lack for experts is severe and very well recognized. The ESRs will quantify the physical impact and suitability of a variety of modalities on Mg implants. Highly sophisticated imaging techniques (nano and µCT, MRT, PET, USPA, IR) will be developed beyond the forefront of medical device production in vivo and with in situ label-ling options to deliver non-invasively data on different time and length scales of the body reac-tion and material behavior during Mg degradation with a precision and plethora of details which is currently not available. Two Mg-alloys and CE-certified Mg-implants will be studied in rats and sheep. Dummy studies will be performed in parallel (following ASTM rules). The ob-tained multimodal imaging data will be combined with molecular biological/biochemical analy-sis, thereby increasing the information about physiological changes without using additional animals. An additional dimension will be added by the analysis of explants to obtain highest resolution chemical and material science data. All relevant biological and chemical in vivo and ex vivo data will be merged by computational 3D methods, simulations and machine learning approaches. The combination of these results will not only allow for an upscaling of the pro-cesses towards humans but will also deliver valuable data in terms of patient safety.

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The information about "MGSAFE" are provided by the European Opendata Portal: CORDIS opendata.

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