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SOS-CROPS SIGNED

Solving the tangled ontogenesis of the stem for sustainable crops

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 SOS-CROPS project word cloud

Explore the words cloud of the SOS-CROPS project. It provides you a very rough idea of what is the project "SOS-CROPS" about.

extensive    edge    mutations    pleiotropic    brassinosteroid    depends    integrates    arabidopsis    me    ga    expression    br    reduce    ath1    genes    valuable    homeobox1    genetic    gibberellin    action    international    crop    levels    plants    signals    benefit    understand    network    polyploid    transition    shape    give    influences    dominant    undesired    persistent    data    structure    stem    broadly    developmental    ways    host    cutting    height    inflorescence    precise    thaliana    quantitative    gene    fundamental    first    crops    fewer    skills    mechanisms    hormonal    flowering    practical    inhibits    repeatedly    editing    yields    time    downregulated    signalling    phenotyping    mode    yield    prior    contacts    productivity    lab    cellular    macroscopic    indicate    cis    subtle    tools    genome    evolution    poorly    plant    mutation    regulatory    reveal    dwarf    career    seed    genetics    training    improvement    modifying    elongation    floral    molecular   

Project "SOS-CROPS" data sheet

The following table provides information about the project.

Coordinator
JOHN INNES CENTRE 

Organization address
address: NORWICH RESEARCH PARK COLNEY
city: NORWICH
postcode: NR4 7UH
website: www.jic.bbsrc.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Total cost 224˙933 €
 EC max contribution 224˙933 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2018
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2019
 Duration (year-month-day) from 2019-05-20   to  2021-06-03

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    JOHN INNES CENTRE UK (NORWICH) coordinator 224˙933.00

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 Project objective

Crop yield depends in a large part on stem height and inflorescence structure. Mutations that reduce stem growth have been used widely to improve crop yields but also have undesired side effects, for example during seed formation. In spite of its importance, stem development is poorly understood. Fundamental knowledge of how genes control stem growth is required to develop more precise genetic tools to increase plant productivity by modifying plant height and shape.

The ARABIDOPSIS THALIANA HOMEOBOX1 (ATH1) gene inhibits stem development but is rapidly downregulated prior to the floral transition to allow elongation of the inflorescence stem. Data from the host lab indicate that ATH1 integrates two of the key hormonal signals that control stem growth: gibberellin (GA) and brassinosteroid (BR). My objectives are to reveal the mode of action of ATH1 and use this knowledge to develop new ways of modifying plant height with fewer undesired side-effects. I will reveal how ATH1 influences GA and BR signalling, understand molecular mechanisms of ATH1 action and identify cis-regulatory mutations that result in dwarf plants due to persistent ATH1 expression after flowering. Such mutations would be particularly useful for two reasons: first, regulatory mutations have been selected repeatedly in evolution and crop improvement because they allow subtle changes in gene expression, with fewer pleiotropic effects. Second, this type of mutation would be expected to be dominant and especially useful in polyploid crops.

In addition to addressing a fundamental problem with practical use, this work will give me cutting edge training in plant developmental genetics and quantitative phenotyping at cellular and macroscopic levels. At the same time, the project will benefit from my knowledge of plant hormonal signalling and extensive experience in genome editing. More broadly, the work will provide me with a valuable network on international contacts and skills for my future career.

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The information about "SOS-CROPS" are provided by the European Opendata Portal: CORDIS opendata.

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