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MeloCRISP SIGNED

Implementation of CRISPR/Cas9 technology in melon to edit fruit ripening and CMV resistant genes

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 MeloCRISP project word cloud

Explore the words cloud of the MeloCRISP project. It provides you a very rough idea of what is the project "MeloCRISP" about.

transfer    breeding    seed    broadest    agronomic    model    mechanism    performed    resistant    engagement    17    oft    strategy    region    post    melon    mapped    climacteric    underlying    phenotypic    global    efforts    emerged    melocrisp    cucumis    priorities    meeting    2016    he    generate    varieties    first    economically    guarantee    time    multidisciplinary    genes    traits    tool    delay    variability    losses    crispr    solanaceae    melo    host    progress    cucumber    causes    valuable    transgenic    market    cmv1    40    virus    biological    15    ultimately    ripening    quality    knockout    programs    worldwide    fruit    species    resistance    outcome    inter    agriculture    demand    genomic    cas9    food    scenario    candidate    substitution    precise    cmv    vegetable    plants    diseases    impair    nucleotide    harvest    ongoing    regulation    functionally    sectorial    genetic    proposes    mosaic    industry    validating    gene    crops    group    approached    crop    editing   

Project "MeloCRISP" data sheet

The following table provides information about the project.

Coordinator
CENTRE DE RECERCA EN AGRIGENOMICA CSIC-IRTA-UAB-UB 

Organization address
address: PARC DE RECERCA DE L UAB CAMPUS UAB EDIFICI CRAG BELLATERRA
city: CERDANYOLA DEL VALLES
postcode: 8193
website: www.cragenomica.es

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Spain [ES]
 Total cost 170˙121 €
 EC max contribution 170˙121 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-EF-CAR
 Starting year 2018
 Duration (year-month-day) from 2018-05-15   to  2020-11-03

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    CENTRE DE RECERCA EN AGRIGENOMICA CSIC-IRTA-UAB-UB ES (CERDANYOLA DEL VALLES) coordinator 170˙121.00

Map

 Project objective

Meeting with global food demand is one of the main priorities in the 2016-17 work programme of H2020. Virus diseases are among the main causes of crop production losses, being Cucumber mosaic virus (CMV) the virus with broadest host range. On the other hand, post-harvest losses are estimated to account for 15-40% of fruit and vegetable production worldwide. In this scenario, several efforts are ongoing to identify genes underlying fruit quality and production such us those related with climacteric ripening and CMV resistance Melon (Cucumis melo L.) is one oft he most economically important group of vegetable crops after Solanaceae, and has emerged as a crop model for important biological traits due to its phenotypic variability and the the availability of genetic and genomic resources. Previous studies at the host group have identified and mapped genes involved in the regulation of climacteric fruit ripening and in a novel mechanism for CMV resistance in this species. MeloCRISP proposes to progress our current understanding on the genomic control of these important agronomic traits by functionally validating the identified candidate genes. The CRISPR/Cas9 system will be implemented for the first time in this species and used for precise gene editing. In order to delay or impair fruit ripening in climacteric varieties, a gene knockout strategy will be approached. On the other hand, a precise nucleotide substitution in the resistance to CMV region (cmv1) will be performed to generate CMV resistant plants The expected outcome is the development of non-transgenic melon CMV resistant plants and varieties with improved fruit quality. This inter-sectorial and multidisciplinary project involves the engagement of a seed industry which will guarantee the transfer of the results to the seed market, ultimately leading to a high impact in the agriculture and food industry sector. Moreover, the implementation of CRISPR/Cas9 will become a valuable tool for melon breeding programs.

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The information about "MELOCRISP" are provided by the European Opendata Portal: CORDIS opendata.

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