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MeloCRISP SIGNED

Implementation of CRISPR/Cas9 technology in melon to edit fruit ripening and CMV resistant genes

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 MeloCRISP project word cloud

Explore the words cloud of the MeloCRISP project. It provides you a very rough idea of what is the project "MeloCRISP" about.

40    causes    transfer    candidate    cucumis    performed    crispr    substitution    cmv    demand    cucumber    scenario    proposes    tool    agriculture    he    virus    ultimately    first    fruit    industry    priorities    economically    cmv1    underlying    efforts    crop    vegetable    diseases    group    traits    sectorial    solanaceae    post    mapped    multidisciplinary    generate    model    phenotypic    editing    species    progress    mosaic    biological    losses    breeding    genomic    functionally    seed    mechanism    ongoing    approached    ripening    crops    meeting    validating    cas9    worldwide    agronomic    2016    nucleotide    melo    genes    melon    programs    market    climacteric    resistant    outcome    knockout    food    time    broadest    precise    emerged    genetic    transgenic    regulation    impair    17    global    strategy    region    quality    engagement    variability    harvest    varieties    inter    plants    gene    resistance    guarantee    delay    melocrisp    valuable    host    oft    15   

Project "MeloCRISP" data sheet

The following table provides information about the project.

Coordinator
CENTRE DE RECERCA EN AGRIGENOMICA CSIC-IRTA-UAB-UB 

Organization address
address: PARC DE RECERCA DE L UAB CAMPUS UAB EDIFICI CRAG BELLATERRA
city: CERDANYOLA DEL VALLES
postcode: 8193
website: www.cragenomica.es

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Spain [ES]
 Total cost 170˙121 €
 EC max contribution 170˙121 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-EF-CAR
 Starting year 2018
 Duration (year-month-day) from 2018-05-15   to  2020-11-03

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    CENTRE DE RECERCA EN AGRIGENOMICA CSIC-IRTA-UAB-UB ES (CERDANYOLA DEL VALLES) coordinator 170˙121.00

Map

 Project objective

Meeting with global food demand is one of the main priorities in the 2016-17 work programme of H2020. Virus diseases are among the main causes of crop production losses, being Cucumber mosaic virus (CMV) the virus with broadest host range. On the other hand, post-harvest losses are estimated to account for 15-40% of fruit and vegetable production worldwide. In this scenario, several efforts are ongoing to identify genes underlying fruit quality and production such us those related with climacteric ripening and CMV resistance Melon (Cucumis melo L.) is one oft he most economically important group of vegetable crops after Solanaceae, and has emerged as a crop model for important biological traits due to its phenotypic variability and the the availability of genetic and genomic resources. Previous studies at the host group have identified and mapped genes involved in the regulation of climacteric fruit ripening and in a novel mechanism for CMV resistance in this species. MeloCRISP proposes to progress our current understanding on the genomic control of these important agronomic traits by functionally validating the identified candidate genes. The CRISPR/Cas9 system will be implemented for the first time in this species and used for precise gene editing. In order to delay or impair fruit ripening in climacteric varieties, a gene knockout strategy will be approached. On the other hand, a precise nucleotide substitution in the resistance to CMV region (cmv1) will be performed to generate CMV resistant plants The expected outcome is the development of non-transgenic melon CMV resistant plants and varieties with improved fruit quality. This inter-sectorial and multidisciplinary project involves the engagement of a seed industry which will guarantee the transfer of the results to the seed market, ultimately leading to a high impact in the agriculture and food industry sector. Moreover, the implementation of CRISPR/Cas9 will become a valuable tool for melon breeding programs.

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The information about "MELOCRISP" are provided by the European Opendata Portal: CORDIS opendata.

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